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71.
72.
近年来,我国各级安全生产监管部门全面落实科学发展观,坚持安全发展的理念,认真履行安全生产综合监管职能,积极探索开展综合监管工作的措施、途径和手段,逐步构筑了“分类指导、职责明晰、条块结合、运行有序、机制完善”的安全生产综合监管机制和总体格局,全国安全生产综合监管建设取得了长足的进步。但是,在综合监管工作实践中,很多地区也都遇到并提出了同样的问题:《安全生产法》等法律法规中并没有对综合监管的内容作出明确的规定。 相似文献
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74.
Chantal Deden Kornelia Neveling Dimitra Zafeiropopoulou Christian Gilissen Rolph Pfundt Tuula Rinne Nicole de Leeuw Brigitte Faas Thatjana Gardeitchik Suzanne C. E. H. Sallevelt Aimee Paulussen Servi J. C. Stevens Esther Sikkel Mariet W. Elting Merel C. van Maarle Karin E. M. Diderich Nicole Corsten-Janssen Klaske D. Lichtenbelt Guus Lachmeijer Lisenka E. L. M. Vissers Helger G. Yntema Marcel Nelen Ilse Feenstra Wendy A. G. van Zelst-Stams 《黑龙江环境通报》2020,40(8):972-983
Objective
The purpose of this study was to explore the diagnostic yield and clinical utility of trio-based rapid whole exome sequencing (rWES) in pregnancies of fetuses with a wide range of congenital anomalies detected by ultrasound imaging.Methods
In this observational study, we analyzed the first 54 cases referred to our laboratory for prenatal rWES to support clinical decision making, after the sonographic detection of fetal congenital anomalies. The most common identified congenital anomalies were skeletal dysplasia (n = 20), multiple major fetal congenital anomalies (n = 17) and intracerebral structural anomalies (n = 7).Results
A conclusive diagnosis was identified in 18 of the 54 cases (33%). Pathogenic variants were detected most often in fetuses with skeletal dysplasia (n = 11) followed by fetuses with multiple major fetal congenital anomalies (n = 4) and intracerebral structural anomalies (n = 3). A survey, completed by the physicians for 37 of 54 cases, indicated that the rWES results impacted clinical decision making in 68% of cases.Conclusions
These results suggest that rWES improves prenatal diagnosis of fetuses with congenital anomalies, and has an important impact on prenatal and peripartum parental and clinical decision making. 相似文献75.
Kiran L. Dhanjal‐Adams Marcel Klaassen Sam Nicol Hugh P. Possingham Iadine Chadès Richard A. Fuller 《Conservation biology》2017,31(3):646-656
Conserving migratory species requires protecting connected habitat along the pathways they travel. Despite recent improvements in tracking animal movements, migratory connectivity remains poorly resolved at a population level for the vast majority of species, thus conservation prioritization is hampered. To address this data limitation, we developed a novel approach to spatial prioritization based on a model of potential connectivity derived from empirical data on species abundance and distance traveled between sites during migration. We applied the approach to migratory shorebirds of the East Asian‐Australasian Flyway. Conservation strategies that prioritized sites based on connectivity and abundance metrics together maintained larger populations of birds than strategies that prioritized sites based only on abundance metrics. The conservation value of a site therefore depended on both its capacity to support migratory animals and its position within the migratory pathway; the loss of crucial sites led to partial or total population collapse. We suggest that conservation approaches that prioritize sites supporting large populations of migrants should, where possible, also include data on the spatial arrangement of sites. 相似文献
76.
The effect of sea-water submergence on rhizome bud viability of the introducedAmmophila arenaria and the nativeLeymus mollis in California 总被引:1,自引:0,他引:1
Ammophila arenaria, an invasive European beach grass, dominates most United States Pacific coast beaches north of San Francisco Bay, and it
appears to severely reduce opportunities for regeneration of native plant species, including American beach grass,Leymus mollis. The knowledge of how longAmmophila rhizomes can survive in sea-water is important for long-tern management strategies, which must consider the probability of
reinvasion of areas whereAmmophila has been eradicated. The bud viability of bothAmmophila arenaria andLeymus mollis remained high following submergence in sea-water for 7 days, andLeymus bud viability was still high after 13 days submergence. In fact,Leymus bud viability appears to be enhanced slightly by submergence for 7 days in sea-water. SinceAmmophila rhizomes retain a mean bud viability of >50% following submergence for 7 days, there is clearly the potential for long distance
dispersal to other beaches. Even after 13 days of submergence,Ammophila rhizomes still had a mean bud viability of 8.5%. Assuming near-shore current speeds of 5–45 cm/sec, viableAmmophila rhizomes can be transported up to 505 km in 13 days. 相似文献
77.
A link between eumelanism and calcium physiology in the barn owl 总被引:3,自引:1,他引:2
In many animals, melanin-based coloration is strongly heritable and is largely insensitive to the environment and body condition. According to the handicap principle, such a trait may not reveal individual quality because the production of different melanin-based colorations often entails similar costs. However, a recent study showed that the production of eumelanin pigments requires relatively large amounts of calcium, potentially implying that melanin-based coloration is associated with physiological processes requiring calcium. If this is the case, eumelanism may be traded-off against other metabolic processes that require the same elements. We used a correlative approach to examine, for the first time, this proposition in the barn owl, a species in which individuals vary in the amount, size, and blackness of eumelanic spots. For this purpose, we measured calcium concentration in the left humerus of 85 dead owls. Results showed that the humeri of heavily spotted individuals had a higher concentration of calcium. This suggests either that plumage spottiness signals the ability to absorb calcium from the diet for both eumelanin production and storage in bones, or that lightly spotted individuals use more calcium for metabolic processes at the expense of calcium storage in bones. Our study supports the idea that eumelanin-based coloration is associated with a number of physiological processes requiring calcium. 相似文献
78.
The 450-million-year-old symbiosis between the majority of land plants and arbuscular mycorrhizal fungi (AMF) is one of the most ancient, abundant, and ecologically important mutualisms on Earth. Yet, the evolutionary stability of mycorrhizal associations is still poorly understood, as it follows none of the constraints thought to stabilize cooperation in other well-known mutualisms. The capacity of both host and symbiont to simultaneously interact with several partners introduces a unique dilemma; detecting and punishing those exploiting the mutualism becomes increasingly difficult if these individuals can continue to access resources from alternative sources. Here, we explore four hypotheses to explain evolutionary cooperation in the arbuscular mycorrhizal symbiosis: (1) pseudo-vertical transmission and spatial structuring of plant and fungal populations leading to local adaptation of partners; (2) luxury resource exchange in which plants trade surplus carbon for excess fungal nutrients; (3) partner choice allowing partners to associate with better cooperators; and (4) host and symbiont sanctions which actively reward good partners and punish less cooperative ones. We propose that mycorrhizal cooperation is promoted by an exchange of surplus resources between partners and enforced through sanctions by one or both partners. These mechanisms may allow plant and fungal genotypes to discriminate against individuals employing exploitative strategies, promoting patterns of partner choice. Together these selection pressures provide a framework for understanding the stabilization of mycorrhizal cooperation over evolutionary time. 相似文献
79.
Oddmund Kleven A. Moksnes Eivin Røskaft Marcel Honza 《Behavioral ecology and sociobiology》1999,47(1-2):41-46
The cuckoo (Cuculus canorus) is an obligate interspecific brood parasite. When about to lay an egg, the female must decide which nest to parasitise.
A high-quality host species should be preferred, to enhance the possibility of producing a viable offspring. In this study,
we investigated the effects of two closely related host species, the great reed warbler (Acrocephalus arundinaceus) and the reed warbler (A. scirpaceus) on the growth rate of cuckoo nestlings. We found that cuckoo nestlings raised by the larger host species, the great reed
warbler, grew significantly faster and became statistically significantly larger at fledging than nestlings raised by the
smaller host, the reed warbler. Our results indicate a qualitative difference between the two host species. The great reed
warbler, considered to be the best host, was parasitised at a higher rate than the reed warbler.
Received: 2 February 1999 / Received in revised form: 3 September 1999 / Accepted: 18 September 1999 相似文献
80.
《中国个体防护装备》编辑部 《中国个体防护装备》2009,(1)
一元复始,辞旧迎新,春回大地,万象更新.在这腊梅傲雪绽放、春雨顺风飘洒之际,<中国个体防护装备>杂志编辑部向社会各界朋友恭贺新年,祝愿大家在新的一年里身体健康、万事如意! 相似文献