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Andrea Springman Braxton Forde Leandra Tolusso Emily DeFranco Daniel T. Swarr E. Deah Wright Mounira Habli 《黑龙江环境通报》2023,43(8):1092-1095
We report a case of a twin-twin transfusion syndrome (TTTS) recipient who, after successful fetoscopic surgery, developed a large pericardial effusion and calcifications of the aorta and main pulmonary artery. The donor fetus never had cardiac strain and never developed cardiac calcifications. A heterozygous likely pathogenic variant in ABCC6 (c.2018T > C, p.Leu673Pro) was identified in the recipient twin. While TTTS recipient twins are at risk of arterial calcifications and right heart failure secondary to the disease, calcifications of the great vessels are also observed in generalized arterial calcification of infancy, a Mendelian genetic disorder with associated biallelic pathogenic variations in ABCC6 or ENPP1, which can result in significant pediatric morbidity or mortality. The recipient twin in this case had some degree of cardiac strain prior to TTTS surgery; however, the progressive calcification of the aorta and pulmonary trunk occurred weeks after TTTS resolution. This case raises the possibility of a gene-environment interaction and emphasizes the need for genetic evaluation in the setting of TTTS and calcifications. 相似文献
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Intraspecific density mediates sex-change in the territorial patellacean limpet Lottia gigantea 总被引:1,自引:0,他引:1
W. G. Wright 《Marine Biology》1989,100(3):353-364
The effects of intraspecific density and agonistic interactions on sex-change were studied in the territorial limpet Lottia gigantea. In a one-year field experiment (1982–1983) on San Nicolas Island off the southern California coast, USA, male limpets transplanted to large enclosures changed sex more frequently than those transplanted to small enclosures (9 of 13 vs 1 of 10; p=0.013), indicating that intraspecific density can profoundly influence the probability of sex change. Large limpets were more likely to change sex than small ones. Observations of gender-age distributions as well as field behavior suggested that each limpet's territorial status prior to the experiment may have been an important component of this size effect, although other interpretations including an effect of age are possible. Pooling the results with those of two previous studies confirmed that sex-change is enhanced by low density. This enhancement was observed among the largest members of a local population in the first year of each experiment, while among the smaller members the enhancement was delayed until the second or third year. Low density may be a correlate of high mortality, and therefore an adaptive cue for an earlier age of sex change. Dominant territorial status correlates with an individual's size, and therefore egg-producing capacity, relative to its neighbors, and thus may also be a good cue for the initiation of sex-change. 相似文献
146.
Ted L. Napier Cathy Wright Moody 《Journal of the American Water Resources Association》1979,15(3):692-705
ABSTRACT: The psychosocial impact of a large water impoundment project upon members of a small farming community located within central Ohio was evaluated using a study-restudy research design. Attitudes toward selected community variables were examined during the initial stages of land acquisition and reevaluated four years later at the completion of the project. The findings revealed that fragmentation of the “social fabric” of the community did not occur. Several statistically significant differences were observed between the two data sets but the findings indicated that community residents held more positive attitudes toward their community following the development action than at the beginning of the project. 相似文献
147.
Allan Curtis Bruce Shindler Angela Wright 《Journal of the American Water Resources Association》2002,38(5):1207-1216
ABSTRACT: In the last decade, watershed groups (WG) established through government initiatives have become an important part of the natural resource management landscape in developed economies. In this paper, the authors reflect upon their research and experience with Landcare in Victoria, and to a lesser extent with Watershed Councils in Oregon, to identify the principles that appear fundamental to sustaining effective WG. In the first instance, these groups must be established at a local scale using social as well as biophysical boundaries. It is also critical that WG are embedded within a supportive institutional framework that identifies realistic roles for private landowners, local organizations such as WG, and regional planning bodies. Without broad stakeholder representation, the perceived benefits of participation are quickly forfeited. It is simply unrealistic to expect an effective network of WG to be sustained without substantial investment by government to provide for program management, group coordination, and cost sharing for on‐ground work. There must also be the commitment and skills within a program to establish processes that build trust and competency amongst citizens and agencies. These principles should also provide a foundation for the critical evaluation of WG programs. 相似文献
148.
Modelling of long-term behaviour of caesium and strontium radionuclides in the Arctic environment and human exposure 总被引:3,自引:0,他引:3
Golikov V Logacheva I Bruk G Shutov V Balonov M Strand P Borghuis S Howard B Wright S 《Journal of environmental radioactivity》2004,74(1-3):159-169
In this paper a compartment model of the highly vulnerable Arctic terrestrial food chain "lichen-reindeer-man" is outlined. Based upon an analysis of measured (137)Cs and (90)Sr contents in lichen and reindeer meat from 1961 up to 2001, site specific model parameters for two regions in north-western Arctic Russia and for Kautokeino municipality in Arctic Norway have been determined. The dynamics of radionuclide activity concentrations in the "lichen-reindeer-man" food chain for all areas was satisfactorily described by a double exponential function with short-term and long-term effective ecological half-lives between 1-2 and 10-12 years, respectively, for both (137)Cs and (90)Sr. Using parameter values derived from the model, life-time internal effective doses due to consumption of reindeer meat by reindeer-breeders after an assumed single pulse deposit of 1 kBq m(-2) of (137)Cs were estimated to be 11.4 mSv (Kola Peninsula), 5 mSv (Nenets Autonomous Area), and 2 mSv (Kautokeino, Norway). Differences in vulnerability to radiocaesium deposition were due to differences in transfer between lichen and reindeer and in diet between the three regions. 相似文献
149.
Cronbach's alpha reliability: Interval estimation,hypothesis testing,and sample size planning
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Cronbach's alpha is one of the most widely used measures of reliability in the social and organizational sciences. Current practice is to report the sample value of Cronbach's alpha reliability, but a confidence interval for the population reliability value also should be reported. The traditional confidence interval for the population value of Cronbach's alpha makes an unnecessarily restrictive assumption that the multiple measurements have equal variances and equal covariances. We propose a confidence interval that does not require equal variances or equal covariances. The results of a simulation study demonstrated that the proposed method performed better than alternative methods. We also present some sample size formulas that approximate the sample size requirements for desired power or desired confidence interval precision. R functions are provided that can be used to implement the proposed confidence interval and sample size methods. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
150.
This research examined relationships between alternative measures of affect and supervisory performance ratings. The first study showed that dispositional rather than state affect significantly predicted supervisory ratings of performance over time. Since the measures of affect differed on both content and temporal dimensions, a follow‐up study was conducted to explicate the results. The second study found that a pleasantness‐based measure of dispositional affect (Berkman, 1971a) again predicted rated performance over time, but activation‐based measures of both dispositional and state affect (using PANAS scales) were not predictive of supervisory evaluations of performance. The implications of these findings in terms of research on affect and the longstanding pursuit of the happy–productive worker are discussed. Copyright © 1999 John Wiley & Sons, Ltd. 相似文献