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排序方式: 共有4512条查询结果,搜索用时 390 毫秒
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Chih-Ping Chen Schu-Rern Chern Wayseen Wang Chen-Chi Lee Wen-Lin Chen Li-Feng Chen Tung-Yao Chang Chin-Yuan Tzen 《黑龙江环境通报》2001,21(5):346-350
A prenatal diagnosis of partial monosomy 18p(18p11.2→pter) and trisomy 21q(21q22.3→qter) in a fetus with alobar holoprosencephaly (HPE) and premaxillary agenesis (PMA) but without the classical Down syndrome phenotype is reported. A 27-year-old primigravida woman was referred for genetic counselling at 21 weeks' gestation due to sonographic findings of craniofacial abnormalities. Level II ultrasonograms manifested alobar HPE and median orofacial cleft. Cytogenetic analysis and fluorescence in situ hybridization (FISH) on cells obtained from amniocentesis revealed partial monosomy 18p and a cryptic duplication of 21q,46,XY,der(18)t(18;21)(p11.2;q22.3), resulting from a maternal t(18;21) reciprocal translocation. The breakpoints were ascertained by molecular genetic analysis. The pregnancy was terminated. Autopsy showed alobar HPE with PMA, pituitary dysplasia, clinodactyly and classical 18p deletion phenotype but without the presence of major typical phenotypic features of Down syndrome. The phenotype of this antenatally diagnosed case is compared with those observed in six previously reported cases with monosomy 18p due to 18;21 translocation. The present study is the first report of concomitant deletion of HPE critical region of chromosome 18p11.3 and cryptic duplication of a small segment of distal chromosome 21q22.3 outside Down syndrome critical region. The present study shows that cytogenetic analyses are important in detecting chromosomal aberrations in pregnancies with prenatally detected craniofacial abnormalities, and adjunctive molecular investigations are useful in elucidating the genetic pathogenesis of dysmorphism. Copyright © 2001 John Wiley & Sons, Ltd. 相似文献
3.
We report on the prenatal diagnosis of ring chromosome 15 in a fetus with increased nuchal fold and intrauterine growth restriction (IUGR). A 27-year-old woman gravida 2, para 1 had normal maternal serum screen tests in the early second trimester of the index pregnancy. Fetal nuchal fold thickening up to 8 mm was incidentally found during the routine obstetric ultrasound scan at 20 weeks' gestation. Amniocentesis was undertaken and the fetal karyotype was found to be 46,XY,r(15) on cytogenetic study. Fluorescence in situ hybridization (FISH) using a telomeric probe of chromosome 15 demonstrated a terminal deletion on the q arm of the ring-shaped chromosome 15. This is the first report of a prenatally diagnosed case of ring chromosome 15. Moreover, nuchal fold thickness in the second trimester may have a role in its prenatal diagnosis. Copyright © 2001 John Wiley & Sons, Ltd. 相似文献
4.
三峡库区中低产土壤重金属含量及其与小麦吸收的关系 总被引:3,自引:0,他引:3
三峡库区中低产土壤的Hg,As,Cr,Pb,Cu五个重金属含量(除渝北区外),均在国家土壤环境质量标准内,属自然背景值一级标准。Cd和Zn高于全国土壤中的平均含量和背景值含量,属二级标准。土壤的重金属含量与土壤母质类型,pH值,阳离子交换量,有机质,无定形铁和物理性粘粒有关,同时存在一定的地域分布。重庆近郊的土壤所有重金属含量相对较高。土壤重金属的可给态或有效性含量极低,锌和铜不是过量,而是不足。小麦籽粒中As,Cr,Pb,Zn,Cu含量低于国家食品对重金属限量标准和小麦籽粒背景值标准,Hg,Cd含量高于国家规定标准。籽粒中的Cu,Zn含量是小麦茎叶中的2.0-2.2倍,而茎叶中的Hg,Pb,As,Cr,Cd含量明显高于籽粒。 相似文献
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6.
Jiao Youzhou Xue Huizan He Chao Wang Zigang Ma Xiaoran Liu Xinxin Liu Liang Chang Chun Petracchini Francesco Li Panpan 《Environment, Development and Sustainability》2022,24(4):4709-4726
Environment, Development and Sustainability - Anaerobic digestion (AD) is an attractive straw resource treatment technology as it can improve the utilization efficiency of straw resource. Raw straw... 相似文献
7.
湿地作为水体与陆地之间的过渡地带,具有独特的生态环境特性,是氮循环反应的关键区域.研究湿地生态系统中的全程氨氧化过程(complete ammonia oxidation,comammox),解析该区域中comammox细菌的分布与群落结构特征,补充了此前该新型氨氧化微生物在湿地生态系统中分布特征的研究空白,对于完善comammox细菌在各种不同生态系统中分布情况的研究具有重要意义.本研究在石臼漾人工湿地中于冬夏两季分别采集了大沟中心、大沟边缘、小沟中心和小沟边缘的表层沉积物样品,利用PCR、荧光定量PCR和amoA功能基因高通量测序等方法,解析人工湿地中comammox细菌的时空分布与群落结构特征.主要研究结果如下:①所有样品中均检测到了comammox细菌,其丰度为1.77×105~4.07×107 copies·g-1.冬季,comammox细菌丰度在大沟中高于氨氧化细菌(ammonia oxidizing bacteria,AOB)和氨氧化古菌(ammonia oxidizing archaea,AOA),在小沟中高于AOB,但低于AOA;夏季,comammox细菌丰度在所有样点中均高于AOB和AOA.②冬夏两季样品中,comammox细菌丰度与底物NH4+-N浓度均呈负相关关系,且夏季样品中呈显著性负相关.③主坐标分析(Principle Coordinate Analysis,PCoA)与多样性分析结果表明,comammox细菌群落结构具有空间异质性,且冬季物种多样性高于夏季. 相似文献
8.
厌氧发酵处理有机废物并合成高价值羧酸盐的技术日趋成熟。尤其是己酸作为产物之一,因其附加值高,易于分离,用途广泛,越来越受到关注。微生物合成己酸需要电子供体及受体。详细介绍了乙醇、乙酸分别作为电子供体、受体合成己酸的机理——逆β氧化反应,总结合成己酸底物以及影响合成的因素(温度、pH值、水力停留时间、竞争路径、氢气分压、底物比例、氮源等)。目前采用科氏梭菌以乙醇为电子供体来合成己酸的技术较成熟,探索了利用乳酸为电子供体合成己酸的代谢机理,并指出开发乳酸转化合成己酸的技术可成为未来发展方向。 相似文献
9.
Xue Han Xin Ji Xuan M Jun-Ling Liu Zhen-Yu He Wei Chang Fei Tang Ai-Lin Liu 《环境科学学报(英文版)》2020,32(1):310-318
Changes in water quality from source water to finished water and tap water at two conventional drinking water treatment plants(DWTPs) were monitored.Beside the routine water quality testing,Caenorhabditis elegans-based toxicity assays and the fluorescence excitation–emission matrices technique were also applied.Both DWTPs supplied drinking water that met government standards.Under current test conditions,both the investigated finished water and tap water samples exhibited stronger lethal,genotoxic and reprotoxic potential than the relative source water sample,and the tap water sample was more lethal but tended to be less genotoxic than the corresponding finished water sample.Meanwhile,the nearly complete removal of tryptophan-like substances and newly generated tyrosine-like substances were observed after the treatment of drinking water,and humic-like substances were identified in the tap water.Based on these findings,toxic pollutants,including genotoxic/reproductive toxicants,are produced in the drinking water treatment and/or distribution processes.Moreover,further studies are needed to clarify the potentially important roles of tyrosine-like and humic-like substances in mediating drinking water toxicity and to identify the potential sources of these contaminants.Additionally,tryptophan-like fluorescence may be adopted as a useful parameter to monitor the treatment performance of DWTPs.Our observations provided insights into the importance of utilizing biotoxicity assays and fluorescence spectroscopy as tools to complement the routine evaluation of drinking water. 相似文献
10.
Ozone pollution characteristics and sensitivity analysis using an observation-based model in Nanjing, Yangtze River Delta Region of China 总被引:1,自引:0,他引:1
Ming Wang Wentai Chen Lin Zhang Wei Qin Yong Zhang Xiangzhi Zhang Xin Xie 《环境科学学报(英文版)》2020,32(7):13-22
Ground-level ozone (O3) has become a critical pollutant impeding air quality improvement in Yangtze River Delta region of China. In this study, we present O3 pollution characteristics based on one-year online measurements during 2016 at an urban site in Nanjing, Jiangsu Province. Then, the sensitivity of O3 to its precursors during 2 O3 pollution episodes in August was analyzed using a box model based on observation (OBM). The relative incremental reactivity (RIR) of hydrocarbons was larger than other precursors, suggesting that hydrocarbons played the dominant role in O3 formation. The RIR values for NOX ranged from –0.41%/% to 0.19%/%. The O3 sensitivity was also analyzed based on relationship of simulated O3 production rates with reductions of VOC and NOX derived from scenario analyses. Simulation results illustrate that O3 formation was between VOCs-limited and transition regime. Xylenes and light alkenes were found to be key species in O3 formation according to RIR values, and their sources were determined using the Positive Matrix Factorization (PMF) model. Paints and solvent use was the largest contributor to xylenes (54%), while petrochemical industry was the most important source to propene (82%). Discussions on VOCs and NOX reduction schemes suggest that the 5% O3 control goal can be achieved by reducing VOCs by 20%. To obtain 10% O3 control goal, VOCs need to be reduced by 30% with VOCs/NOX larger than 3:1. 相似文献