Biologie und Biochemie des Elements Selen

The importance of selenium as an essential trace element has progressively emerged during the last years due to the analysis of selenium deficiency diseases and to the identification and characterization of a number of selenoenzymes. Selenium is incorporated in the catalytic site of the enzymes as an integral selenocysteine residue. The pathway of selenocysteine biosynthesis and incorporation has been elucidated recently for Escherichia coli. This article presents an overview on these subjects and describes the mechanisms which confer selenocysteine specificity in the framework of protein biosynthesis. In addition, some considerations concerning the phylogeny of selenocysteine incorporation are presented and a model for the evolution of the selenocysteine pathway is proposed.     

A polyiodide with regular I 4 2− chains: Tl6PbI10

The Science of Nature -     

Über die Wirkung von N-(4-Methyl-benzolsulfonyl)-N′-butyl-harnstoff auf die Glukose-6-Phosphatase der Leber

The Science of Nature -     

The ecological basis of boll weevil (Anthonomus grandis Boheman) management

The boll weevil (Anthonomus grandis Boheman), generally considered to be native to Mexico or Central America, spread into the southern United States of America in the late 1800s and seriously threatened the cotton industry. As there were no effective alternatives, pest control specialists studied the insect's ecology and advocated cultural practices that would disrupt its environment and maximize the benefits of natural biological and environmental controls. An ecologically orientated pest management scheme founded on cultural practices emerged well before suitable chemical control technology became available and allowed farmers to live with the weevil problem.Despite the ingenuity of the early management scheme, it frequently did not provide satisfactory boll weevil control gauged by present standards. Control of the pest thus shifted largely from an ecological to a chemical approach as effective synthetic organic insecticides became available after World War II. The chemical approach was successful for a number of years, but problems of insecticide-resistant strains of pests, secondary pest outbreaks, environmental quality, and increased costs of the insecticides have forced pest control specialists to re-emphasize the nonchemical techniques used widely against the boll weevil before World War II and to revive the ecological approach to weevil management.This article examines boll weevil ecology as related to management of the insect and reviews the status and prospects of ecologically-based weevil management techniques in the United States.     

Prenatal diagnosis of mosaic 4p – in a fetus with trisomy 21

Mosaicism for the Wolf-Hirschhorn syndrome, del(4)(p16), is extremely rare and has not been reported in association with a numerical chromosome abnormality. We report the prenatal diagnosis of mosaic del(4)(p16) and non-mosaic trisomy 21 in a 16-week female fetus. The pregnancy ended in spontaneous abortion at 34 weeks secondary to fetal demise. The fetus had features of both 4p – and trisomy 21.