Vulnerability of Indian mustard (<Emphasis Type="Italic">Brassica juncea</Emphasis> (L.) Czernj. Cosson) to climate variability and future adaptation strategies

A simulation study has been carried out using the InfoCrop mustard model to assess the impact of climate change and adaptation gains and to delineate the vulnerable regions for mustard (Brassica juncea (L.) Czernj. Cosson) production in India. On an all India basis, climate change is projected to reduce mustard grain yield by ～2 % in 2020 (2010–2039), ～7.9 % in 2050 (2040–2069) and ～15 % in 2080 (2070–2099) climate scenarios of MIROC3.2.HI (a global climate model) and Providing Regional Climates for Impact Studies (PRECIS, a regional climate model) models, if no adaptation is followed. However, spatiotemporal variations exist for the magnitude of impacts. Yield is projected to reduce in regions with current mean seasonal temperature regimes above 25/10 °C during crop growth. Adapting to climate change through a combination of improved input efficiency, additional fertilizers and adjusting the sowing time of current varieties can increase yield by ～17 %. With improved varieties, yield can be enhanced by ～25 % in 2020 climate scenario. But, projected benefits may reduce thereafter. Development of short-duration varieties and improved crop husbandry becomes essential for sustaining mustard yield in future climates. As climatically suitable period for mustard cultivation may reduce in future, short-duration (<130 days) cultivars with 63 % pod filling period will become more adaptable. There is a need to look beyond the suggested adaptation strategy to minimize the yield reduction in net vulnerable regions.     

Conducting polymers/zinc oxide-based photocatalysts for environmental remediation: a review

The accessibility to clean water is essential for humans, yet nearly 250 million people die yearly due to contamination by cholera, dysentery, arsenicosis, hepatitis A, polio, typhoid fever, schistosomiasis, malaria, and lead poisoning, according to the World Health Organization. Therefore, advanced materials and techniques are needed to remove contaminants. Here, we review nanohybrids combining conducting polymers and zinc oxide for the photocatalytic purification of waters, with focus on in situ polymerization, template synthesis, sol–gel method, and mixing of semiconductors. Advantages include less corrosion of zinc oxide, less charge recombination and more visible light absorption, up to 53%.

     

Prenatal exposure to environmental pro-oxidants induces mitochondria-mediated epigenetic changes: a cross-sectional pilot study

Mitochondria play a central role in maintaining cellular and metabolic homeostasis during vital development cycles of foetal growth. Optimal mitochondrial functions are important not only to sustain adequate energy production but also for regulated epigenetic programming. However, these organelles are subtle targets of environmental exposures, and any perturbance in the defined mitochondrial machinery during the developmental stage can lead to the re-programming of the foetal epigenetic landscape. As these modifications can be transferred to subsequent generations, we herein performed a cross-sectional study to have an in-depth understanding of this intricate phenomenon. The study was conducted with two arms: whereas the first group consisted of in utero pro-oxidant exposed individuals and the second group included controls. Our results showed higher levels of oxidative mtDNA damage and associated integrated stress response among the exposed individuals. These disturbances were found to be closely related to the observed discrepancies in mitochondrial biogenesis. The exposed group showed mtDNA hypermethylation and changes in allied mitochondrial functioning. Altered expression of mitomiRs and their respective target genes in the exposed group indicated the possibilities of a disturbed mitochondrial-nuclear cross talk. This was further confirmed by the modified activity of the mitochondrial stress regulators and pro-inflammatory mediators among the exposed group. Importantly, the disturbed DNMT functioning, hypermethylation of nuclear DNA, and higher degree of post-translational histone modifications established the existence of aberrant epigenetic modifications in the exposed individuals. Overall, our results demonstrate the first molecular insights of in utero pro-oxidant exposure associated changes in the mitochondrial-epigenetic axis. Although, our study might not cement an exposure-response relationship for any particular environmental pro-oxidant, but suffice to establish a dogma of mito-epigenetic reprogramming at intrauterine milieu with chronic illness, a hitherto unreported interaction.

Graphical abstract

     

Role of environmental lead in the occurrence of anemia in Indian children: a systematic review and meta-analysis

Environmental Science and Pollution Research - Exposure to lead among children, as well as adults, is a major global health issue. With diverse routes of exposure (e.g., food, air, and water)...