Relationship between blood concentrations of heavy metals and cytogenetic and endocrine parameters among subjects involved in cleaning coastal areas affected by the 'Prestige' tanker oil spill

The sinking of the 'Prestige' oil tanker in front of the Galician coast (NW of Spain) in November 2002 offered a unique opportunity to analyze intermediate cytogenetic and endocrine effects among people exposed to the complex mixture of substances that oil constitutes, including several toxic heavy metals. In this work we evaluated the relationship between exposure to heavy metals (blood concentrations of aluminium, cadmium, nickel, lead and zinc) and genotoxic parameters (sister chromatid exchanges, micronucleus test and comet assay) or endocrine parameters (plasmatic concentrations of prolactin and cortisol) in subjects exposed to 'Prestige' oil during cleaning tasks developed after the spillage. Concentrations of lead were significantly related to the comet assay even after adjusting by age, sex and smoking. Cortisol concentrations were significantly influenced by aluminium, nickel (both, inversely) and cadmium (positively). Women had clearly higher concentrations of prolactin and cortisol, even when adjusting by age, smoking, cadmium, aluminium or nickel. Plasmatic cortisol was jointly influenced by gender, smoking and aluminium or nickel (all p<0.05). In women there was a strong relationship between concentrations of cadmium and prolactin (beta=0.37, p=0.031). When the effects of cadmium, aluminium and nickel on cortisol were simultaneously assessed, only the latter two metals remained statistically significant. Among parameters analysed, cortisol appeared to be the most sensitive to the effects of metal exposure. Plasma levels of cortisol deserve further evaluation as a potentially relevant biomarker to assess the effects of exposure to heavy metals.     

The relationship between blood alcohol concentration (BAC), age, and crash risk

PROBLEM: The role of age (youth and driving inexperience) and alcohol as major risk factors in traffic crash causation has been firmly established by numerous studies over the past 50 years. Less well established is how the two variables interrelate to influence crash risk. Some investigations have hypothesized an interactive or synergistic effect in which young drivers with less experience and a greater tendency to take risks are more adversely affected at lower blood alcohol concentrations (BACs) than are older drivers. The evidence for this hypothesis is mixed. Resolution of this issue has important implication for developing countermeasures directed at the young driver crash problem. METHOD: Case control data previously collected in Long Beach and Fort Lauderdale were reanalyzed using a more sensitive method for detecting interaction effects than used in the original analysis. A conditional logistic regression analyses found a highly significant agexBAC interaction (P<.0001) involving differences between drivers under 21 and those 21 and older. DISCUSSION: The results clearly indicate that positive BACs in drivers under 21 are associated with higher relative crash risks than would be predicted from the additive effect of BAC and age. It is likely that two mechanisms are operating to cause the interaction. First, it seems likely that the crash avoidance skill of young novice drivers would be more adversely affected by alcohol due to their driving inexperience, immaturity, and less experience with alcohol. Second, drivers under 21 who choose to drink and to drive after drinking probably have pre-existing characteristics that predisposed them to risk taking and crash involvement apart from any increased vulnerability to alcohol impairment. IMPACT ON INDUSTRY: The results support increased enforcement of zero-tolerance BAC laws for minors.     

Unmanned aerial vehicle images in the machine learning for agave detection

Environmental Science and Pollution Research - In this study, six supervised classification algorithms were compared. The algorithms were based on cluster analysis, distance, deep learning, and...     

Phosphorus mass balance and input load estimation from the wet and dry periods in tropical semiarid reservoirs

The dynamics of total phosphorus (TP) in 18 strategic reservoirs of the high-density reservoir network of the Brazilian semiarid was evaluated during the wet and dry periods for the past 12 years. Seasonal overlying concentrations presented no significant differences for about 90% of the reservoirs (p>0.05). This was attributed to a trade-off between the hydrological/limnological processes occurring in the two seasons. Then, a transient complete-mix mass balance model was applied with particular adaptations for the tropical semiarid reservoirs to estimate the TP load for each season. Because of the relatively well-mixed conditions and high hypolimnetic dissolved oxygen concentrations during the wet season, the wet load was assumed to represent the external TP load. On the other hand, because of the absence of reservoir inflow during the dry season, phosphorus release under anoxic sediment conditions and wind-induced resuspension under shallow water depths, the dry load was assumed to reflect the internal TP load. The maximum external loads were related to peak inflows, notably after drought periods. Consistently, the largest internal loads were obtained during the drought periods, when the reservoirs were shallower and more prone to phosphorus release and resuspension. By comparing the impact of the two input load types, the wet period load was predominant in 72% of the reservoirs. The areal phosphorus loads ranged from 0.66 to 7.29 gP m² year^?1, which were consistent with the literature, despite the very high density of reservoirs. Finally, power-law curves including data for all studied reservoirs were adjusted between the dry period load and volume, dry and wet period loads, wet period load and inflow, and total load and catchment area, resulting in satisfactory R² (0.84–0.98).

     

Ionic Dye Removal Using Solvent-Assisted Ionic Micellar Flocculation

Journal of Polymers and the Environment - The environmental impacts caused by dyes in industrial wastewater are incalculable, due to their adverse effects on the ecosystem and human life,...     

Electrocatalytic conversion of nitrate waste into ammonia: a review

Environmental Chemistry Letters - The electrocatalytic reduction of nitrate waste into ammonia allows both the removal of nitrate contaminants and an alternative production of ammonia compared to...     

Mining tailings and alkali activation: a comprehensive bibliometric review

Environmental Science and Pollution Research - Significant amounts of mining tailings are generated and disposed of every year in dams, leading to potentially serious environmental and safety...     

Annealing Effect on Pla/Eva Blends Performance

Journal of Polymers and the Environment - PLA has aroused industrial and scientific interest in recent years, mainly due to its biodegradable character. However, PLA is brittle and displays low...