The influence of natural stressors on the toxicity of nickel to <Emphasis Type="Italic">Daphnia magna</Emphasis>

Global warming has become a source of awareness regarding the potential deleterious effects of extreme abiotic factors (e.g., temperature, dissolved oxygen (DO) levels) and also their influence on chemicals toxicity. In this work, we studied the combined effects of nickel and temperature (low and high levels) and nickel and low levels of DO to Daphnia magna, and concentration addition and independent action concepts as well as their deviations for synergism/antagonism, dose ratio and dose level dependency, were applied to survival and feeding rate data. Nickel single exposure showed an LC₅₀ value for 48 h of 7.36 mg l⁻¹ and an EC₅₀ value for feeding impairment at 2.41 mg l⁻¹. In the acute exposures to high and low temperatures, 50% of mortality was observed, respectively, at 30.7°C and 4.2°C whereas 50% reduction on the feeding activity was recorded at 22.6°C and 16.0°C. Relatively to low DO levels, a LC₅₀ value for 48 h of 0.5 mg l⁻¹ was obtained; feeding activity EC₅₀ value was 2 mg l⁻¹. On acute combined experiments, antagonism was observed for the combination of nickel and extreme temperatures, whereas a synergistic behaviour was observed in the combined exposure of nickel and low DO levels. At sublethal levels, nickel showed to be the main inducer of toxicity at high and low temperatures but not at low levels of dissolved oxygen. Toxicokinetics and toxicodynamics modelling studies should be made in the future to understand the toxicological pathways involved on complex combinations of stressors and to validate any conclusions.     

Derivation of motor vehicle tailpipe particle emission factors suitable for modelling urban fleet emissions and air quality assessments

Background, aim and scope  

Urban motor vehicle fleets are a major source of particulate matter pollution, especially of ultrafine particles (diameters < 0.1 μm), and exposure to particulate matter has known serious health effects. A considerable body of literature is available on vehicle particle emission factors derived using a wide range of different measurement methods for different particle sizes, conducted in different parts of the world. Therefore, the choice as to which are the most suitable particle emission factors to use in transport modelling and health impact assessments presented as a very difficult task. The aim of this study was to derive a comprehensive set of tailpipe particle emission factors for different vehicle and road type combinations, covering the full size range of particles emitted, which are suitable for modelling urban fleet emissions.     

Host community attitudes towards solid waste landfill infrastructure: comprehension before compensation

One of the most controversial planning issues internationally is the siting of waste disposal infrastructure in local communities. Compensation is viewed as a possible solution to siting difficulties in many countries. However, existing empirical evidence is conflicting as to whether or not compensation-based siting has reduced opposition to such developments. Thus, before compensation policy can be considered as the solution for recognising social costs and introducing equity into the waste planning system, it is important to understand why people reject waste disposal infrastructure developments and if this rejection continues over the lifetime of facility operations. This paper utilises information gathered through surveys to examine the effects of distance, local authority consultation efforts, experience and other factors, on attitudes towards non-hazardous solid waste landfill developments in two examples of a potential and actual host communities. Our findings suggest distance proxies expectations of environmental risk in communities with no experience of living with landfill infrastructure. Community consultations by authorities are consistently important, even after a landfill has been in operation for a number of years. This suggests to policy makers to consult thoroughly and adequately before pursuing compensation policies.     

Educating citizens about their coastal environments: beach profiling in the Coastwatch project

The Coastwatch (CW) project is aimed at monitoring the coastline with the involvement of volunteers. Between 2003 and 2007 a beach profiling method was informally proposed to CW participants in Portugal as an extra activity to include in the surveys. Beach profiling contributes to a better understanding of coastal processes by providing quantitative information on the spatial/temporal evolution of beaches, which is crucial for coastal management. The profiling method proposed to the CW project is based on the physical principle of communicating vessels, and only requires a simple and inexpensive homemade ??profiler??. The simplicity of putting together and using the profiler, added to the arithmetic straightforwardness of data analysis, makes this method adequate for several kinds of users and for most levels of education. Eight workshops were held that included a classroom explanation of the method, the construction of a profiler, the actual profiling of a beach, and a final classroom session of data processing and graphing. About 140 participants received such training, and several among them independently undertook beach profiling. Surveyed participants found the workshop and the beach profiling method interesting and useful, and considered it a valuable tool for teaching and for management. External stakeholders (coastal managers) highlighted the importance of beach profiling data for management decisions and considered that this method produces robust data, even when carried out by volunteers. Further advantages of the application of the method, in the context of coastal management initiatives, for scientists, managers, and volunteers are discussed.     

Statistical analysis in MSW collection performance assessment

The increase of Municipal Solid Waste (MSW) generated over the last years forces waste managers pursuing more effective collection schemes, technically viable, environmentally effective and economically sustainable. The assessment of MSW services using performance indicators plays a crucial role for improving service quality. In this work, we focus on the relevance of regular system monitoring as a service assessment tool. In particular, we select and test a core-set of MSW collection performance indicators (effective collection distance, effective collection time and effective fuel consumption) that highlights collection system strengths and weaknesses and supports pro-active management decision-making and strategic planning. A statistical analysis was conducted with data collected in mixed collection system of Oporto Municipality, Portugal, during one year, a week per month. This analysis provides collection circuits’ operational assessment and supports effective short-term municipality collection strategies at the level of, e.g., collection frequency and timetables, and type of containers.     

Life cycle assessment of a packaging waste recycling system in Portugal

Life Cycle Assessment (LCA) has been used to assess the environmental impacts associated with an activity or product life cycle. It has also been applied to assess the environmental performance related to waste management activities. This study analyses the packaging waste management system of a local public authority in Portugal. The operations of selective and refuse collection, sorting, recycling, landfilling and incineration of packaging waste were considered. The packaging waste management system in operation in 2010, which we called “Baseline” scenario, was compared with two hypothetical scenarios where all the packaging waste that was selectively collected in 2010 would undergo the refuse collection system and would be sent directly to incineration (called “Incineration” scenario) or to landfill (“Landfill” scenario). Overall, the results show that the “Baseline” scenario is more environmentally sound than the hypothetical scenarios.     

Ketoprofen Loaded in Natural Rubber Latex Transdermal Patch for Tendinitis Treatment

Ketoprofen is an analgesic with potent anti-inflammatory activity against acute inflammation, subacute inflammation, for the acute and long-term treatment of various inflammatory pathologies, as rheumatoid arthritis and colonic adenocarcinoma. In order to minimize the incidence of systemic events related to ketoprofen, the transdermal drug delivery system development has been most important. The advantages of using natural rubber latex membranes include not only the reduction of adverse systemic events, but also the suitability of the low cost of the material together with its physicochemical properties such as flexibility, mechanical stability, surface porosity and water vapor permeability, and besides being a biocompatible material also presents biological activity to stimulate the angiogenesis, being able to be used in tissue repair. This study demonstrated that ketoprofen was successfully incorporated into natural latex membranes for drug delivery. FTIR indicated that the drug did not interact chemically with the membrane. Moreover, the natural latex membranes released 60% of the ketoprofen incorporated in 50 h. SEM images indicated that a portion of the drug was present on the membrane surface, being this portion responsible for the burst release. The tensile tests showed that the addition of the drug into the natural latex membrane did not influence on the polymer mechanical behavior. In addition, drug-natural latex membranes presented no red blood cell damaging effects. Our data shows that the ketoprofen loaded natural latex membranes is a promising system for sustained drug delivery which can be used to minimize the adverse side effects of high dose systemic drug delivery.