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Advances in molecular cytogenetics, especially the technique of fluorescence in situ hybridization (FISH), have allowed more precise definition of chromosomal structures, which are difficult to identify using conventional G-banding. Recently, a novel approach based on hybridization of 24 fluorescent-labelled chromosome painting probes was developed, termed spectral karyotyping (SKY), which allows the simultaneous and differential colour display of all human chromosomes. We have used SKY to identify not only five parental complex translocation carriers but also minute chromosome rearrangements in the fetus. Here, we concentrate attention on the clinical application of SKY for prenatal diagnosis. Copyright © 2001 John Wiley & Sons, Ltd. 相似文献
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Yasushi?SekineEmail author Kaoru?Fujimoto 《Journal of Material Cycles and Waste Management》2003,5(2):107-112
We investigated the function of Fe and activated carbon (AC) as a catalyst by comparing Fe/AC with Fe/SiO2 or AC, and also the effect of H2 as a reaction gas on the product distribution in the catalytic degradation of polypropylene. Supported Fe promotes H2 consumption to decompose solid residues, and AC support degrades heavy oil to produce light oil. As a result, using Fe/AC as a catalyst gives the maximum yield of the liquid product. For the reaction conditions, with a high reaction temperature or a long reaction time, the product distribution is more influenced by the thermal degradation than by the catalytic degradation. For the amount of Fe to load, 5wt% is the optimum condition in our reaction system. We demonstrated the mechanism of the degradation of polyolefins with hydrogen-capping catalysts. 相似文献
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Teruhito Otsuka Hiroyasu Saitoh Takaaki Mizutani Kaoru Morimoto Norihiko Yoshikawa 《Journal of Loss Prevention in the Process Industries》2007,20(4-6):427-432
Deflagration phenomena in hydrogen–air mixtures initially filled in 1.4 m3 spherical latex balloons were measured using a high-speed digital video camera and pressure transducers. The image velocimetry using brightness subtraction was introduced to eliminate the background effects for obtaining accurate time evolution records of flame propagation velocity. The maximum flame propagation velocity of about 100 m/s was observed with maximum overpressure 15 kPa at 1 m from ignition point. According to the detailed flame propagation velocity records, there were long deceleration durations. The observed maximum overpressure was smaller than the overpressure estimated by the basis of the observed maximum flame propagation velocity and the pressure wave theories of spherical flames. A new blast curve plot of scaled overpressure vs. distance was tentatively proposed. 相似文献
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