人为因素对社会-生态系统脆弱性和恢复力影响的地理差异

横跨北极的地区,可更新资源和不可更新资源、人口密度、资产投资、住宅与交通基础设施的分布存在着很大差异,这些差异被公认为是研究当前和未来社会-生态系统变化的热点.由于当前政治和经济的稳定,芬诺斯堪的亚地区北部社会-生态系统呈现出相对良好的形势,而俄罗斯北部从苏联解体开始便一直经历着急速且消极的变化,这些变化反映了俄罗斯普遍存在的危机状态.北美洲虽然处在一个相对稳定有序的制度下,采取了一些措施用于防止和减轻与工业有关的环境退化,但大多即将出台的新发展计划仍将会显著扩大社会-生态系统受到潜在影响的空间范围.制度或管理条款与生态系统服务功能对环境变化的缓冲能力紧密相关.无论气候是否变暖,某些地理区域对外来破坏作用表现得特别脆弱,这有可能威胁到这些区域在将来提供产品和服务的能力.尽管某些地区的气候变化有可能会使这种形势恶化,但从长远来看,气候变化也有可能会使其恢复力得到加强.     

Human chorionic gonadotropin levels in pregnancies with aneuploid fetuses

Maternal serum human chorionic gonadotropin (hCG) and the free alpha-hCG subunit were evaluated in 249 women from 9 to 11 weeks gestation who subsequently underwent chorionic villus sampling for determination of fetal karyotype and in 20 women of 18 or more weeks gestation who were ascertained to have an aneuploid fetus by genetic amniocentesis. Seven of the first-trimester pregnancies were determined to be aneuploid and six had hCG levels in the normal range (one triploid pregnancy had elevated hCG levels) whereas 12 of the 20 secondtrimester cases had abnormal hCG levels and an additional three had elevated levels of alpha-hCG. This study confirms the previous report of abnormal maternal serum hCG levels in women with an aneuploid fetus at ≥ 18 weeks gestation and demonstrates that hCG evaluation is not useful at 9–11 weeks gestation for selecting pregnancies at risk for fetal aneuploidy.     

Identification of a novel β0 - thalassaemia mutation in a greek family and subsequent prenatal diagnosis

We present a case in which a Greek couple was considered not to be at risk of having children with homozygous β-thalassaemia, an assessment based largely on the father's belief that he carried α-thalassaemia. After their first child was diagnosed with homozygous β-thalassaemia, the case was re-assessed and both parents were shown to have the haematological profile of β-thalassaemia trait. Screening for the common Mediterranean mutations demonstrated that the mother carries the IVS-1 nt 110 G→A β⁺ -thalassaemia mutation. Direct nucleotide sequencing of PCR-amplified DNA revealed that the father carries a novel β⁰-thalassaemia mutation, frameshift codons 9/10 (+T). The couple's second pregnancy was terminated after prenatal testing revealed that the fetus had inherited both parental mutations. This case illustrates the need to confirm the carrier status of individuals prior to assessing their genetic risks, and highlights the importance of being able to identify rare or novel β-thalassaemia mutations.     

Fetal renal vein thrombosis,hydrops fetalis,and maternal lupus anticoagulant. A case report

Hydrops fetalis with fetal renal vein thrombosis in a mother with antiphospholipid antibody syndrome detected post-partum suggests an underlying pathogenetic association that may provide new strategies for treatment of a lethal disorder.     

An infant with trisomy 9 mosaicism presenting as a complete trisomy 9 by amniocentesis

We present a case in which amniocentesis performed at 33 weeks' gestation because of symmetrical intrauterine growth retardation and decreased amniotic fluid volume led to the prenatal diagnosis of a fetus with a karyotype of 47,XX,+9, t(1;20)(q42;p11.2) pat, i.e., with an extra chromosome 9 and a balanced translocation between chromosomes 1 and 20. At delivery, the baby showed clinical features of trisomy 9, yet chromosome analysis of the cord blood revealed no trisomy 9 cells, a finding confirmed by neonatal blood karyotyping. The balanced translocation was present in all cells. A skin biopsy confirmed trisomy 9 mosaicism with 10 per cent trisomy 9 cells. The baby died at 6 weeks and an autopsy was obtained. Chromosome analysis of different organs demonstrated different frequencies of the mosaicism of trisomy 9. The possible underlying mechanism for the discrepancy between the karyotype results by amniocentesis and those of other tissues is discussed.     

The Role of the Concept of the Natural (Naturalness) in Organic Farming

Producers, traders, and consumers oforganic food regularly use the concept of thenatural (naturalness) to characterize organicagriculture and or organic food, in contrast tothe unnaturalness of conventional agriculture.Critics sometimes argue that such use lacks anyrational (scientific) basis and only refers tosentiment. In our project, we made an attemptto clarify the content and the use of theconcepts of nature and naturalness in organicagriculture, to relate this conception todiscussions within bioethical literature, andto draw the implications for agriculturalpractice and policy.Qualitative interviews were executed with arange of people in the field of organicagriculture and with consumers of organicproducts, on the basis of a list of statementsabout the meaning of the concept of naturalnessformulated by the authors. Based on the resultsof the interviews, we distinguished 3 aspectsof the concept of naturalness: natural as theorganic (life processes), natural as theecological, and natural as referring to thecharacteristic nature of an entity. We relatedthese conceptual aspects to three mainapproaches within the field of organicagriculture: the no chemicals approach, theagro-ecological approach, and the integrityapproach. It became clear that these approachescan also be recognized in the change ofattitude of farmers as they convert fromconventional to organic agriculture, and in theattitudes of consumers of organic foodproducts.We conclude that the idea of ``naturalness' canbe used to characterize organic agriculture andto distinguish it from conventionalagriculture, but only if naturalness not onlyrefers to not using chemicals but also toecological principles and respect for theintegrity of life. Thus perceived, theprinciple of naturalness can also serve as aguide to future developments in the field oforganic agriculture. As part of the holocentricethics of organic farming the value ofnaturalness has three dimensions: a cognitiveone, an emotive one, and a normative one.     

Remote measurement of NO2 in the brown cloud over Albuquerque,New Mexico

Remote measurements of nitrogen dioxide (NO₂) were recorded in the brown cloud over Albuquerque, NM, using absorption spectroscopy in the winter of 1987-88 and summer of 1989. The NO₂ burdens (optical densities) measured in this manner were found to be in excess of 100 ppm-m. These long pathlength measurements correspond to total concentrations of approximately 5–10 ppb over the integrated observation pathlengths, which ranged from 10–20 km. These concentrations compare well with single location, independent NO _x analyses. Using two correlation (absorption) spectrometers simultaneously, it was shown that the NO₂ distribution is not uniform over the city and can change on the order of minutes in the boundary layer late in the day, demonstrating the advantages of NO₂ optical measurements for assessing the location and extent of urban nitrogen dioxide levels in the boundary layer.     

Diversity in the later Paleogene proboscidean radiation: a small barytheriid from the Oligocene of Dhofar Governorate,Sultanate of Oman

Despite significant recent improvements to our understanding of the early evolution of the Order Proboscidea (elephants and their extinct relatives), geographic sampling of the group’s Paleogene fossil record remains strongly biased, with the first ~30 million years of proboscidean evolution documented solely in near-coastal deposits of northern Africa. The considerable morphological disparity that is observable among the late Eocene and early Oligocene proboscideans of northern Africa suggests that other, as yet unsampled, parts of Afro-Arabia might have served as important centers for the early diversification of major proboscidean clades. Here we describe the oldest taxonomically diagnostic remains of a fossil proboscidean from the Arabian Peninsula, a partial mandible of Omanitherium dhofarensis (new genus and species), from near the base of the early Oligocene Shizar Member of the Ashawq Formation, in the Dhofar Governorate of the Sultanate of Oman. The molars and premolars of Omanitherium are morphologically intermediate between those of Arcanotherium and Barytherium from northern Africa, but its specialized lower incisors are unlike those of other known Paleogene proboscideans in being greatly enlarged, high-crowned, conical, and tusk-like. Omanitherium is consistently placed close to late Eocene Barytherium in our phylogenetic analyses, and we place the new genus in the Family Barytheriidae. Some features of Omanitherium, such as tusk-like lower second incisors, the possible loss of the lower central incisors, an enlarged anterior mental foramen, and inferred elongate mandibular symphysis and diminutive P₂, suggest a possible phylogenetic link with Deinotheriidae, an extinct family of proboscideans whose origins have long been mysterious.