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191.
Jeffrey S. Duncan Martha T. Fernandez Patricia L. Abbitt Siva Thiagarajah Stuart S. Howards W. Allen Hogge M.D. 《黑龙江环境通报》1990,10(3):175-182
To delineate the natural history of fetal multicystic dysplastic kidneys (MDKs), all cases that were prenatally detected in the Prenatal Diagnosis Center of the University of Virginia from September 1985 to 31 August 1988 were reviewed. All patients were followed through the Center with serial ultrasound evaluations at approximately 4-week intervals, and each liveborn infant was evaluated and followed by one of the authors (S.S.H.) Of the 14 cases detected, ten were detected in the second trimester, the earliest at 16·5 weeks' gestation. Of the nine fetuses with non-lethal disease, there were two cases in which the lesion remained unchanged during observation. Both had an initial diagnosis in the third trimester. In those cases diagnosed in the second trimester (7), all showed an initial increase in the size and number of cysts, followed by involutional changes either in utero (2) or in the neonatal period (3). Two infants had immediate surgical removal of the MDK, one because of respiratory compromise, and the other because of an uncertain diagnosis on renal scan. Abnormalities of the contralateral kidney were found in 7 of 14 fetuses. Five were lethal conditions. Associated non-renal abnormalities were common in bilateral MDK (80 per cent), but rare in unilateral MDK (11 per cent). 相似文献
192.
Hypertrophic cardiomyopathy usually manifests clinically in the second or third decade of life. Two dimensional echocardiography is a reliable indicator of the presence of the disease. This technique is of use in the screening of fetuses at risk for familial cardiomyopathy. This report describes the prenatal echocardiographic detection of hypertrophic cardiomyopathy in the fetus of a mother with hypertrophic cardiomyopathy localized to the apical region of the left ventricle. 相似文献
193.
Ten placentae from pregnancies proceeding to term from mothers who on routine screening at 16–18 weeks gestation were found to have a raised serum AFP but no increase in amniotic fluid AFP and no fetal abnormality, were studied using morphometric techniques. The results were compared with 20 placentae from normal term pregnancies where the maternal serum AFP level was not elevated. The mean total placental volume, volume of parenchyma and villous surface area were increased in the placentae associated with a raised maternal serum AFP. More of these placentae were infarcted and the fetal-placental weight ratio was significantly lower. The hypothesis that elevation of maternal serum AFP level is related to the increase in placental size is addressed. 相似文献
194.
Marcia Marques Monica Ferreira da Costa Maria Irles de O. Mayorga Patricia R.C.Pinheiro 《Ambio-人类环境杂志》2004,33(1):58-66
发展中国家中正面临经济发展挑战的那些人口密集的流域盆地和海岸带地区可能会在各种问题上受到中度或严重的环境影响.这些由巴西东北部至南部流向大西洋海岸的汇水盆地包括广阔的气候带和多种生态系统.盆地边界以内分布着大西洋雨林、大范围的半干旱热带旱生林(caatinga)、广阔的树木及灌木林地(cerrado)、巴西6670km 海岸线的一大部分及其海洋生态系统.在过去的几十年中,这些自然资源上的人类活动不断发展.海滨化已给沿海生境及生物群落造成了沉重的负担.caatinga和cerrado中的大部分原生植被遭到了破坏,仅存留了7%的大西洋原始雨林.河口、海湾和沿海泻湖也遭到了无法恢复的破坏.土地使用、筑坝和分水等活动已成为造成生境丧失和水生生态系统改变的主要原因.尽管巴西东北部地区的干旱和东南部及南部地区的富庶和工业化之间形成明显反差,但给上述两种地区的生境和生物群落造成的影响是同样严重的.阻止环境恶化的努力没有见到效果.为此建议,应该实行将重点集中在水生生态系统完整性的一些更加综合性的环境政策,而不是把重点单独地集中在自然资源上. 相似文献
195.
Levario-Carrillo M Amato D Ostrosky-Wegman P González-Horta C Corona Y Sanin LH 《Chemosphere》2004,55(10):1421-1427
The increased use of organophosphorus insecticides in agriculture and their widespread existence in the environment poses a potential health hazard. To determine the relationship between exposure to pesticides and intrauterine growth retardation (IUGR), live newborns from singleton pregnancies, with (n = 79) and without (n = 292) IUGR were studied. During the gestational period the mothers were living in agricultural communities in the state of Chihuahua, Mexico. Exposure to agrochemical products was evaluated. A significant association between the history of positive exposure to pesticides (i.e. the women themselves or their newborns who showed acetylcholinesterase activity levels lower than 20%) and the presence of IUGR was found. The proportions of exposure in the cases were 18% and 8% in the control group; the adjusted OR (fat free mass, anti-cytomegalovirus antibodies and placental weight) was 2.33 (p = 0.04). 相似文献
196.
The goal of the regional haze mitigation program in the United States is to attain "natural conditions" in national parks and wilderness areas by 2064. Results of research investigations on background concentrations of sea salt and biogenic organic matter, of episodic Saharan and Asian dust, and of carbon from natural fires were reviewed to provide a basis for making site-specific estimates of what the concentrations of atmospheric fine particulate matter components might be under natural conditions in the Southeastern United States. Based on this review, rough estimates were made of potential contributions of these aerosol components to natural background visibility. Natural organic particles were the dominant influence on the rate of visibility improvement required to reach natural conditions at an inland, mountainous location, and organic particles and sea salt were the dominant influences on the rate at a coastal location. African dust also had a large episodic effect, but the current regulatory approach is not designed to address episodic background variations. Insufficient data exist to quantify the contributions of wildfires with any detail, although global air pollution modeling provides insight, and their emissions can be locally dominant. Conservative regional refinements to the default natural background estimates do not greatly alter the region-wide rates of reduction of ambient particulate matter concentrations that will be needed to accomplish the first phase of the regional haze program. However, refinements at specific Class I areas may have considerable influence on defining the nature (magnitude and spatial and temporal distribution) of local emission reduction efforts there. 相似文献
197.
Dimensionless Life Histories and Effective Population Size 总被引:3,自引:0,他引:3
The effective size ( N e ) of a population can be estimated from demographic information. We evaluated a recent model, showing that N e depends strongly on the relationship between age at reproductive maturity ( M ) and average adult lifespan ( A ). N e converges on half the number of potentially reproducing adults ( N/2 ) as M decreases relative to A , but it increases linearly as M increases for a given value of A . Therefore, convergence of N e on N/2 is more likely in organisms with a short sexual maturation period scaled to adult lifespan. To assess the generality of this convergence we asked whether most organisms are characterized by this requisite relationship between M and A . The dimensionless number M/A is approximately invariant within taxa, but it is markedly different across taxa. Previous work focused on birds and mammals, taxa with unusually small M/A (0.4 and 0.75). Other animal taxa take longer than most birds and mammals to reach maturity for a given reproductive lifespan, so they are characterized by larger M/A (e.g., fish, 2.0). In theory, these taxon-specific life histories strongly influence N e . We conclude that N e is expected to approach N/2 , provided that M/A is (unusually) small, and that N e / N among poikilotherms may often exceed that of mammals and especially birds. 相似文献
198.
199.
Huang V Sakata JT Rhen T Coomber P Simmonds S Crews D 《Die Naturwissenschaften》2008,95(12):1137-1142
Kratochvil et al. (Naturwissenschaften 95:209–215, 2008) reported recently that in the leopard gecko (Eublepharis macularius) of the family Eublepharidae with temperature-dependent sex determination (TSD), clutches in which eggs were incubated at
the same temperature produce only same-sex siblings. Interpreting this result in light of studies of sex steroid hormone involvement
in sex determination, they suggested that maternally derived yolk steroid hormones could constrain sex-determining mechanisms
in TSD reptiles. We have worked extensively with this species and have routinely incubated clutches at constant temperatures.
To test the consistency of high frequency same-sex clutches across different incubation temperatures, we examined our records
of clutches at the University of Texas at Austin from 1992 to 2001. We observed that clutches in which eggs were incubated
at the same incubation temperature produced mixed-sex clutches as well as same-sex clutches. Furthermore, cases in which eggs
within a clutch were separated and incubated at different temperatures produced the expected number of mixed-sex clutches.
These results suggest that maternal influences on sex determination are secondary relative to incubation temperature effects. 相似文献
200.
Morris RE McNally DE Tesche TW Tonnesen G Boylan JW Brewer P 《Journal of the Air & Waste Management Association (1995)》2005,55(11):1694-1708
The Visibility Improvement State and Tribal Association of the Southeast (VISTAS) is one of five Regional Planning Organizations that is charged with the management of haze, visibility, and other regional air quality issues in the United States. The VISTAS Phase I work effort modeled three episodes (January 2002, July 1999, and July 2001) to identify the optimal model configuration(s) to be used for the 2002 annual modeling in Phase II. Using model configurations recommended in the Phase I analysis, 2002 annual meteorological (Mesoscale Meterological Model [MM5]), emissions (Sparse Matrix Operator Kernal Emissions [SMOKE]), and air quality (Community Multiscale Air Quality [CMAQ]) simulations were performed on a 36-km grid covering the continental United States and a 12-km grid covering the Eastern United States. Model estimates were then compared against observations. This paper presents the results of the preliminary CMAQ model performance evaluation for the initial 2002 annual base case simulation. Model performance is presented for the Eastern United States using speciated fine particle concentration and wet deposition measurements from several monitoring networks. Initial results indicate fairly good performance for sulfate with fractional bias values generally within +/-20%. Nitrate is overestimated in the winter by approximately +50% and underestimated in the summer by more than -100%. Organic carbon exhibits a large summer underestimation bias of approximately -100% with much improved performance seen in the winter with a bias near zero. Performance for elemental carbon is reasonable with fractional bias values within +/- 40%. Other fine particulate (soil) and coarse particular matter exhibit large (80-150%) overestimation in the winter but improved performance in the summer. The preliminary 2002 CMAQ runs identified several areas of enhancements to improve model performance, including revised temporal allocation factors for ammonia emissions to improve nitrate performance and addressing missing processes in the secondary organic aerosol module to improve OC performance. 相似文献