Effect of repeated oral administration of hexachlorophene (HCP) on glycolytic and oxidative pathways was studied in the rat brain. The rats were divided into three batches of six in each batch. The first batch was treated with paralytic dose (60 mg.kg-1.day-1) of HCP for 7 days. The second batch of animals was treated with sublethal dose (18 mg.kg-1.day-1) for 7 days. The third batch of animals was served as the age matched controls which received vehicle (corn oil) only. The glycolytic and oxidative metabolism of carbohydrates was significantly inhibited in the brain of rat during HCP treatment and the inhibition was more pronounced in paralytic dose treatment as compared to sublethal dose treatment. The inhibition of NADP-isocitrate dehydrogenase coupled with glucose 6-phosphate dehydrogenase indicates reduced generation of NADPH2 and pentoses for the synthesis of fatty acids and nucleotides. 相似文献
Exposure of a freshwater teleost, Sarotherodon mossambicus, to a sublethal concentration (26 ppm) of carbon tetrachloride for periods up to 30 days led to significant changes in the soluble protein fractions (albumin and globulins) and free amino acid content. the decrease in total protein content was greater in liver than in muscle. the protein loss was expected due to the impairement of protein synthetic activity during stress conditions. 相似文献
Environmental Science and Pollution Research - Oil spills are a major contributor to water contamination, which sets off a significant impact on the environment, biodiversity, and economy.... 相似文献
Numerous contaminants in huge amounts are discharged to the environment from various anthropogenic activities. Waterbodies are one of the major receivers of these contaminants. The contaminated water can pose serious threats to humans and animals, by distrubing the ecosystem. In treating the contaminated water, adsorption processes have attained significant maturity due to lower cost, easy operation and environmental friendliness. The adsorption process uses various adsorbent materials and some of emerging adsorbent materials include carbon- and polymer-based magnetic nanocomposites. These hybrid magnetic nanocomposites have attained extensive applications in water treatment technologies due to their magnetic properties as well as combination of unique characteristics of organic and inorganic elements. Carbon- and polymer-related magnetic nanocomposites are more adapted materials for the removal of various kinds of contaminants from waterbodies. These nanocomposites can be produced via different approaches such as filling, pulse-laser irradiation, ball milling, and electro-spinning. This comprehensive review is compiled by reviewing published work of last the latest recent 3 years. The review article extensively focuses on different approaches for producing various carbon- and polymer-based magnetic nanocomposites, their merits and demerits and applications for sustainable water purification. More specifically, use of carbon- and polymer-based magnetic nanocomposites for removal of heavy metal ions and dyes is discussed in detail, critically analyzed and compared with other technologies. In addition, commercial viability in terms of regeneration of adsorbents is also reviewed. Furthermore, the future challenges and prospects in employing magnetic nanocomposites for contaminant removal from various water sources are presented.
人类和其他生物通过多重途径暴露于大量的环境污染物中。单一化合物由于其在环境中非常低的浓度使得人们忽视其可能的健康危害,然而,多种化合物在环境中同时存在,就意味着更加复杂的联合作用的可能性。Something from nothing现象引起了科学界对于环境混合物加和作用和潜在协同作用的关注,致使许多研究联合毒性的数学和生物模型的提出和应用。本文综述了这些研究方法,以及未来化学混合物研究和管理面临的挑战。 相似文献
The toxic effects of an organophosphorous insecticide, monochrotophos (MCP) were investigated on Paramecium caudatum in static acute toxicity tests (10?min and 2?h). The lethal concentrations (50%) were determined by probit method, for technical monocrotophos as 60 and 40.6?mg?L?1, respectively. We have combined conventional light microscopy and a computerized video tracking system to determine behavioural and morphological changes in paramecium on exposure to MCP. Paramecia exposed to highest concentrations (90–100?mg?L?1) used for 10?min exposure, exhibited initial increase with subsequent decrease in mobility with enormous blebbing, leading to lysis of cells. In the second set of experiments, the cells exposed to lethal concentration (40.6?mg?L?1) for 2?h were under stress, and reduced their locomotor behaviour, i.e. distance travelled per unit time (mm in 6?min) and swimming speed (mm?s?1) with increased time of exposure. In the third set of experiments, the number of generations and generation time in 24?h was evaluated with respect to the different sub lethal concentrations (5, 10, 15 and 20?mg?L?1) of toxicant. The number of generations decreased and generation time extended significantly in a concentration dependent manner. The results indicate that the Paramecium toxicity assay could be used as a complimentary system to rapidly elucidate the cytotoxic potential of insecticides. 相似文献
Socio-economic development of mankind and well-being depend on the environment and the way in which development influences the environment. Thus, environment and development are interdependent. In fact, economic development is closely linked with the development of resources. These resources can be classified into three categories: public goods, semi-public goods (also known as common property resources) and private goods. In poor countries common property resources make a valuable contribution to the sustainable livelihoods of rural populations. The impact of globalisation on the commons shows various patterns of ownership, control, use and misuse. The commons were subjected to degradation as well as conservation in the process of centralized management in India. After the reform period, the administration of natural resources was given significant attention by specialized departments such as the Forest Department and the Revenue Department. All the land, apart from private land, was regarded as state property and controlled by the state. This paper highlights the need to examine the common property resources sector in the context of wider economic policy reform processes in the Indian economy. 相似文献
An assessment of human interference in Kedarnath Wildlife Sanctuary (KWLS) showed huge dependence of local communities on forest fringes. KWLS is under active consideration as a national park because of its unique flora and fauna. Studies have evidenced habitat destruction and successional changes in the area because of ongoing unsustainable harvesting and logging. The present study provides an integrated approach towards evaluating resource extraction and management of the sanctuary. The study was based on in-depth semi-structured interviews and group discussions with local inhabitants of six villages and with forest officials. In addition, regeneration patterns and vegetation analysis was conducted in three land tenurial systems: community forest (CF), reserve forest (RF) and protected forest (PF). Key issues identified were wildlife offences, encroachment, pressure from unsustainable harvesting of resources and lack of livelihood opportunities. Ecological studies showed continuous change in regeneration patterns in forest patches/stands. The local survey stressed managing sanctuary fringes considering the village economy, social issues and resource requirements, and enhancing on-farm resource production to reduce pressure on forests. Forest personnel demanded more training on encroachment and poaching, these being major threats to biodiversity and bio-resources. Supporting and providing better livelihood opportunities is a viable option for minimizing pressure and managing biodiversity of the area through active community participation. This study generated useful outcomes and strategies for advancing policies to reduce pressure and overcome management constraints in the sanctuary. 相似文献