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771.
The disinfection of drinking water is a major public health achievement; however, an unintended consequence of disinfection is the generation of disinfection by-products (DBPs). Many of the identified DBPs exhibit in vitro and in vivo toxicity, generate a diversity of adverse biological effects, and may be hazards to the public health and the environment. Only a few DBPs are regulated by several national and international agencies and it is not clear if these regulated DBPs are the forcing agents that drive the observed toxicity and their associated health effects. In this study, we combine analytical chemical and biological data to resolve the forcing agents associated with mammalian cell cytotoxicity of drinking water samples from three cities. These data suggest that the trihalomethanes (THMs) and haloacetic acids may be a small component of the overall cytotoxicity of the organic material isolated from disinfected drinking water. Chemical classes of nitrogen-containing DBPs, such as the haloacetonitriles and haloacetamides, appear to be the major forcing agents of toxicity in these samples. These findings may have important implications for the design of epidemiological studies that primarily rely on the levels of THMs to define DBP exposure among populations. The TIC-Tox approach constitutes a beginning step in the process of identifying the forcing agents of toxicity in disinfected water. 相似文献
772.
Clara H. Jeong Edward J. Machek Morteza Shakeri Stephen E. Duirk Thomas A. Ternes Susan D. Richardson Elizabeth D. Wagner Michael J. Plewa 《环境科学学报(英文版)》2017,29(8):173-182
The presence of iodinated X-ray contrast media (ICM) in source waters is of high concern to public health because of their potential to generate highly toxic disinfection by-products (DBPs). The objective of this study was to determine the impact of ICM in source waters and the type of disinfectant on the overall toxicity of DBP mixtures and to determine which ICM and reaction conditions give rise to toxic by-products. Source waters collected from Akron, OH were treated with five different ICMs, including iopamidol, iopromide, iohexol, diatrizoate and iomeprol, with or without chlorine or chloramine disinfection. The reaction product mixtures were concentrated with XAD resins and the mammalian cell cytotoxicity and genotoxicity of the reaction mixture concentrates was measured. Water containing iopamidol generated an enhanced level of mammalian cell cytotoxicity and genotoxicity after disinfection. While chlorine disinfection with iopamidol resulted in the highest cytotoxicity overall, the relative iopamidol-mediated increase in toxicity was greater when chloramine was used as the disinfectant compared with chlorine. Four other ICMs (iopromide, iohexol, diatrizoate, and iomeprol) expressed some cytotoxicity over the control without any disinfection, and induced higher cytotoxicity when chlorinated. Only iohexol enhanced genotoxicity compared to the chlorinated source water. 相似文献
773.
<正>The disinfection of drinking water was an outstanding(and perhaps the most important)public health achievement of the 20~(th) century.According to the United Nations World Health Organization,over 4 billion people have access to 相似文献
774.
Regina Keller Jason A. Tetro V. Susan Springthorpe Syed A. Sattar 《Food and environmental virology》2010,2(2):97-100
Human noroviral infections are generally more common during winters in temperate regions. This study used a murine norovirus
(MNV) as a human norovirus surrogate to test the effect of water temperature (4 and 25°C) on virus survival and its susceptibility
to the levels of monochloramine (~1.89 ppm) to terminally disinfect municipally treated potable waters. The titre of MNV remained
essentially unchanged for at least 24 h in raw river water at both temperatures. The virus became undetectable in <2 h in
monochloramine-containing samples held at 25°C, but its titre remained virtually unaltered at 4°C (P < 0.05) under the same conditions. These findings strongly suggest that water temperature can influence the norovirucidal
activity of monochloramine and its possible impact on the seasonality of outbreaks of noroviral infections. 相似文献
775.
Breadfruit (Artocarpus altilis, Moraceae) is a traditionally cultivated, high-energy, high-yield crop, but widespread use of the plant for food is limited
by poor quality and poor storage properties of the fruit. A unique field genebank of breadfruit species and cultivars exists
at the National Tropical Botanical Garden in the Hawaiian Islands and is an important global resource for conservation and
sustainable use of breadfruit. However, this plant collection could be damaged by a random natural disaster such as a hurricane.
We have developed a highly efficient in vitro plant propagation system to maintain, conserve, mass propagate, and distribute
elite varieties of this important tree species. Mature axillary shoot buds were collected from three different cultivars of
breadfruit and proliferated using a cytokinin-supplemented medium. The multiple shoots were maintained as stock cultures and
repeatedly used to develop whole plants after root differentiation on a basal or an auxin-containing medium. The plantlets
were successfully grown under greenhouse conditions and were reused to initiate additional shoot cultures for sustained production
of plants. Flow cytometry was used to determine the nuclear deoxyribonucleic acid content and the ploidy status of the in
vitro grown population. The efficacy of the micropropagation protocols developed in this study represents a significant advancement
in the conservation and sustained mass propagation of breadfruit germplasm in a controlled environment free from contamination. 相似文献
776.
Sharks are apex predators, and their evolutionary success is in part due to an impressive array of sensory systems, including
vision. The eyes of sharks are well developed and function over a wide range of light levels. However, whilst close relatives
of the sharks—the rays and chimaeras—are known to have the potential for colour vision, an evolutionary trait thought to provide
distinct survival advantages, evidence for colour vision in sharks remains equivocal. Using single-receptor microspectrophotometry,
we measured the absorbance spectra of visual pigments located in the retinal photoreceptors of 17 species of shark. We show
that, while the spectral tuning of the rod (wavelength of maximum absorbance, λmax 484–518 nm) and cone (λmax 532–561 nm) visual pigments varies between species, each shark has only a single long-wavelength-sensitive cone type. This
suggests that sharks may be cone monochromats and, therefore, potentially colour blind. Whilst cone monochromacy on land is
rare, it may be a common strategy in the marine environment: many aquatic mammals (whales, dolphins and seals) also possess
only a single, green-sensitive cone type. It appears that both sharks and marine mammals may have arrived at the same visual
design by convergent evolution. The spectral tuning of the rod and cone pigments of sharks is also discussed in relation to
their visual ecology. 相似文献
777.
778.
779.
Tina L. Cheng Jonathan D. Reichard Jeremy T. H. Coleman Theodore J. Weller Wayne E. Thogmartin Brian E. Reichert Alyssa B. Bennett Hugh G. Broders Joshua Campbell Katherine Etchison Daniel J. Feller Richard Geboy Traci Hemberger Carl Herzog Alan C. Hicks Sandra Houghton Jessica Humber Joseph A. Kath R. Andrew King Susan C. Loeb Ariane Massé Katrina M. Morris Holly Niederriter Gerda Nordquist Roger W. Perry Richard J. Reynolds D. Blake Sasse Michael R. Scafini Richard C. Stark Craig W. Stihler Steven C. Thomas Gregory G. Turner Shevenell Webb Bradford J. Westrich Winifred F. Frick 《Conservation biology》2021,35(5):1586-1597
Assessing the scope and severity of threats is necessary for evaluating impacts on populations to inform conservation planning. Quantitative threat assessment often requires monitoring programs that provide reliable data over relevant spatial and temporal scales, yet such programs can be difficult to justify until there is an apparent stressor. Leveraging efforts of wildlife management agencies to record winter counts of hibernating bats, we collated data for 5 species from over 200 sites across 27 U.S. states and 2 Canadian provinces from 1995 to 2018 to determine the impact of white-nose syndrome (WNS), a deadly disease of hibernating bats. We estimated declines of winter counts of bat colonies at sites where the invasive fungus that causes WNS (Pseudogymnoascus destructans) had been detected to assess the threat impact of WNS. Three species undergoing species status assessment by the U.S. Fish and Wildlife Service (Myotis septentrionalis, Myotis lucifugus, and Perimyotis subflavus) declined by more than 90%, which warrants classifying the severity of the WNS threat as extreme based on criteria used by NatureServe. The scope of the WNS threat as defined by NatureServe criteria was large (36% of Myotis lucifugus range) to pervasive (79% of Myotis septentrionalis range) for these species. Declines for 2 other species (Myotis sodalis and Eptesicus fuscus) were less severe but still qualified as moderate to serious based on NatureServe criteria. Data-sharing across jurisdictions provided a comprehensive evaluation of scope and severity of the threat of WNS and indicated regional differences that can inform response efforts at international, national, and state or provincial jurisdictions. We assessed the threat impact of an emerging infectious disease by uniting monitoring efforts across jurisdictional boundaries and demonstrated the importance of coordinated monitoring programs, such as the North American Bat Monitoring Program (NABat), for data-driven conservation assessments and planning. 相似文献
780.
Laurance WF Nascimento HE Laurance SG Andrade AC Fearnside PM Ribeiro JE Capretz RL 《Ecology》2006,87(2):469-482
The effects of habitat fragmentation on diverse tropical tree communities are poorly understood. Over a 20-year period we monitored the density of 52 tree species in nine predominantly successional genera (Annona, Bellucia, Cecropia, Croton, Goupia, Jacaranda, Miconia, Pourouma, Vismia) in fragmented and continuous Amazonian forests. We also evaluated the relative importance of soil, topographic, forest dynamic, and landscape variables in explaining the abundance and species composition of successional trees. Data were collected within 66 permanent 1-ha plots within a large (approximately 1000 km2) experimental landscape, with forest fragments ranging from 1 to 100 ha in area. Prior to forest fragmentation, successional trees were uncommon, typically comprising 2-3% of all trees (> or =10 cm diameter at breast height [1.3 m above the ground surface]) in each plot. Following fragmentation, the density and basal area of successional trees increased rapidly. By 13-17 years after fragmentation, successional trees had tripled in abundance in fragment and edge plots and constituted more than a quarter of all trees in some plots. Fragment age had strong, positive effects on the density and basal area of successional trees, with no indication of a plateau in these variables, suggesting that successional species could become even more abundant in fragments over time. Nonetheless, the 52 species differed greatly in their responses to fragmentation and forest edges. Some disturbance-favoring pioneers (e.g., Cecropia sciadophylla, Vismia guianensis, V. amazonica, V. bemerguii, Miconia cf. crassinervia) increased by >1000% in density on edge plots, whereas over a third (19 of 52) of all species remained constant or declined in numbers. Species responses to fragmentation were effectively predicted by their median growth rate in nearby intact forest, suggesting that faster-growing species have a strong advantage in forest fragments. An ordination analysis revealed three main gradients in successional-species composition across our study area. Species gradients were most strongly influenced by the standlevel rate of tree mortality on each plot and by the number of nearby forest edges. Species-composition also varied significantly among different cattle ranches, which differed in their surrounding matrices and disturbance histories. These same variables were also the best predictors of total successional-tree abundance and species richness. Successional-tree assemblages in fragment interior plots (>150 m from edge), which are subjected to fragment area effects but not edge effects, did not differ significantly from those in intact forest, indicating that area effects per se had little influence on successional trees. Soils and topography also had little discernable effect on these species. Collectively, our results indicate that successional-tree species proliferate rapidly in fragmented Amazonian forests, largely as a result of chronically elevated tree mortality near forest edges and possibly an increased seed rain from successional plants growing in nearby degraded habitats. The proliferation of fast-growing successional trees and correlated decline of old-growth trees will have important effects on species composition, forest dynamics, carbon storage, and nutrient cycling in fragmented forests. 相似文献