Ecotoxicity of imidacloprid to soil invertebrates in two tropical soils with contrasting texture

Environmental Science and Pollution Research - Imidacloprid is one of the most commercialized insecticides in agriculture in the world, with a broad spectrum of action. However, little is known...     

Solar radiation synthetic series for power purchase agreements

The present paper proposes a methodology based on the implementation and assessment of autoregressive (AR) solar radiation models for generating synthetic series and providing guidance on bidding strategies for power purchase agreements. The work considered conventional and periodic AR models with different lag orders, assessing the models against real solar radiation measurements. The synthetic series generation process developed 1000 1-year monthly solar radiation scenarios that were later employed for simulating electric energy production and power purchase agreement models. This application allowed one to evaluate the risk associated with the energy supply security, supporting bidding strategies in energy auctions. A real study case is also illustrated in detail, referring to a spot in the Brazilian best irradiance area.

     

Carnauba (Copernicia prunifera) palm tree biomass as adsorbent for Pb(II) and Cd(II) from water medium

Environmental Science and Pollution Research - Plant-based biomass (CFB (carnauba fruit biomass)) obtained from the fruit exocarp of the species Copernicia prunifera (Mill.) H.E. Moore (carnauba)...     

Protective effect of gamma-oryzanol against manganese-induced toxicity in Drosophila melanogaster

Environmental Science and Pollution Research - Manganese (Mn) is an essential element that, in excess, seems to be involved in the development of different neurodegenerative conditions....     

Continuous process applied to degradation of triclosan and 2.8-dichlorodibenzene-p-dioxin

Environmental Science and Pollution Research - This study describes the use of a prototype for the continuous photocatalytic reaction process using Fe/Nb2O5-immobilized catalyst for triclosan and...     

Occurrence and risk assessment of organophosphate esters in urban rivers from Piracicaba watershed (Brazil)

Environmental Science and Pollution Research - Organophosphate esters (OPEs) are substances globally used as flame retardants and plasticizers that have been detected in all environmental...     

Cartap removal from simulated water matrices by fluidized-bed Fenton process: optimization of process parameters

Environmental Science and Pollution Research - Cartap is a thiocarbamate pesticide widely-used to protect rice crops, one of the most mass-produced cereals worldwide. Effluents...     

Chemometric tools applied to optimize a fast solid-phase microextraction method for analysis of polycyclic aromatic hydrocarbons in produced water

Environmental Science and Pollution Research - Chemometric tools are powerful strategies to efficiently optimize many processes. These tools were employed to optimize a fast-solid phase...     

All-in-one whole exome sequencing strategy with simultaneous copy number variant,single nucleotide variant and absence-of-heterozygosity analysis in fetuses with structural ultrasound anomalies: A 1-year experience

Objective

We performed a 1-year evaluation of a novel strategy of simultaneously analyzing single nucleotide variants (SNVs), copy number variants (CNVs) and copy-number-neutral Absence-of-Heterozygosity from Whole Exome Sequencing (WES) data for prenatal diagnosis of fetuses with ultrasound (US) anomalies and a non-causative QF-PCR result.

Methods

After invasive diagnostics, whole exome parent-offspring trio-sequencing with exome-wide CNV analysis was performed in pregnancies with fetal US anomalies and a non-causative QF-PCR result (WES-CNV). On request, additional SNV-analysis, restricted to (the) requested gene panel(s) only (with the option of whole exome SNV-analysis afterward) was performed simultaneously (WES-CNV/SNV) or as rapid SNV-re-analysis, following a normal CNV analysis.

Results

In total, 415 prenatal samples were included. Following a non-causative QF-PCR result, WES-CNV analysis was initially requested for 74.3% of the chorionic villus (CV) samples and 45% of the amniotic fluid (AF) samples. In case WES-CNV analysis did not reveal a causative aberration, SNV-re-analysis was requested in 41.7% of the CV samples and 17.5% of the AF samples. All initial analyses could be finished within 2 weeks after sampling. For SNV-re-analysis during pregnancy, turn-around-times (TATs) varied between one and 8 days.

Conclusion

We show a highly efficient all-in-one WES-based strategy, with short TATs, and the option of rapid SNV-re-analysis after a normal CNV result.     

低温诱导海蜇螅状体横裂生殖的分子信号调控机制初探

海蜇生活史是由有性生殖的水母体世代和无性生殖的螅状体世代组成的。海蜇螅状体的无性繁殖是决定水母种群大小的主要繁殖方式。而作为螅状体无性生殖方式之一的横裂生殖是螅状体世代向水母体世代转变的唯一途径,其发生主要受温度调控。本研究对海蜇螅状体进行短期低温培养,比较分析低温诱导组和对照组螅状体转录组的差异,初步探究低温诱导对海蜇螅状体横裂生殖的影响及横裂生殖过程中的分子调控机制。研究结果显示,海蜇螅状体横裂生殖过程中出现1655条差异基因,分属于细胞生长、增殖、分化等信号转导通路,如转化生长因子信号通路（transforming growth factor beta, TGF-β）、丝裂原活化蛋白激酶信号通路（mitogen-activated protein kinase, MAPK）、细胞外分泌蛋白信号通路（wingless-int, Wnt）以及细胞周期介导的信号通路（Cell Cycle）等。在低温诱导下,上述信号通路均有所响应,但总体来看Wnt信号通路被抑制,其他3条通路被激活。通过分析,本研究初步展示了参与低温诱导海蜇螅状体横裂生殖的分子调控途径,为深入揭示海蜇横裂生殖的分子调控机制提供思路。