Prenatal diagnosis of X-linked retinitis pigmentosa (RP) in five pregnancies at risk

Five pregnancies at risk for X-linked retinitis pigmentosa (RP) have been monitored by first-trimester prenatal diagnosis using DNA markers flanking the RP2 and RP3 loci. Three affected and two unaffected fetuses, including a female carrying a wild-type genotype, were predicted on the basis of marker segregation and estimation of the recombination fraction.     

Influencing factors on sustainable development: a case study in Quang Tri province,Vietnam

Background Sustainable development (SD) is a common concept. Knowledge and attitudes are essential in the SD process. This study assesses the knowledge, attitudes, and practices (KAP) of local people about SD. Aim To study the factors that influence the understanding of the concept, contents, and indicators of different aspects affecting the health and environmental issues. Methods A cross-sectional study was carried out from June to July 2007 among 546 households in the Quang Tri province. Data were gathered on basis of socio-demographic variables, namely age, gender, education, occupation, income, and region. Chi square tests and multivariate analysis were performed on the obtained data. The data were cleaned and analysed using SPSS 15.0 for windows. Results Occupation is related to knowledge, attitude, or practice. Income is related to knowledge or practice. Gender related to only attitude. Lastly, region is related to attitude or practice. The proportion of wrong understanding about SD is 2.0 times (95% CI: 1.3; 3.1, p < 0.001) higher than that of the people who have good understanding about it. The rate of willingness to do any related SD programmes of the people who understanding is 2.1 times (95% CI: 1.4; 3.2, p < 0.001) higher than that of the people who have bad one. Conclusions This study shows that knowledge on sustainability of the local communities is low. Occupation and income influence understanding of SD more than region, age, gender, and education. Most of the local people who do not understand SD in general, do not want to participate or act in SD programmes.     

下坪渗滤液处理厂含氨尾气处理试验研究

对下坪垃圾填埋场含氨尾气的处理进行了研究.研究结果显示,采用硫酸吸收含氨尾气,吸收效率可达98%以上.吸收产生的硫酸铵产品符合<肥料、土壤调理剂-硫酸铵标准>(GB535-1995).     

Maternal exposure to specific perfluoroalkyl substances is associated with increasing blood glucose in pregnant women

正Imagine if a group of toxic substances that increase oxidative stress and disrupt glucose and lipid metabolism have been broadly used worldwide for applications such as repellent,food packaging,and non-stick frying pan coatings.Now imagine if some of these substances have half-lives as long as 3-8 years.This is an environmental reality that has come to light with perfluoroalkyl and polyfluoroalkyl substances(PFASs)–high     

吸附-厌氧序批式反应器对有机物的去除

用全脂奶粉配制废水,研究了吸附-厌氧序批式反应器(AB-ASBR)对有机物的去除效果和特性,并与普通厌氧序批式反应器(ASBR)进行了比较.结果表明,AB-ASBR 能显著提高出水水质,当原水COD 为2000mg/L 时,其出水COD 在100mg/L 以下,COD 总去除率可达95%~96%.A 段进水后30min 内对COD 的去除率可达90%,以厌氧颗粒污泥对非溶解性COD 的初期快速吸附作用为主.B 段的半饱和常数(Ks)仅为5.4mg/L,厌氧颗粒污泥对COD 具有很好的亲和性,使B 段出水COD 低于普通厌氧序批式反应器.     

Roles of survival and dispersal in reintroduction success of Griffon vulture (Gyps fulvus).

The success of reintroduction programs greatly depends on the amount of mortality and dispersal of the released individuals. Although local environmental pressures are likely to play an important role in these processes, they have rarely been investigated because of the lack of spatial replicates of reintroduction. In the present study, we analyzed a 25-year data set encompassing 272 individuals released in five reintroduction programs of Griffon Vultures (Gyps fulvus) in France to examine the respective roles of survival and dispersal in program successes and failures. We use recent developments in multi-strata capture-recapture models to take into account tag loss in survival estimates and to consider and estimate dispersal among release areas. We also examined the effects of sex, age, time, area, and release status on survival, and we tested whether dispersal patterns among release areas were consistent with habitat selection theories. Results indicated that the survival of released adults was reduced during the first year after release, with no difference between sexes. Taking into account local observations only, we found that early survival rates varied across sites. However when we distinguished dispersal from mortality, early survival rates became equal across release sites. It thus appears that among reintroduction programs difference in failure and success was due to differential dispersal among release sites. We revealed asymmetrical patterns of dispersal due to conspecific attraction: dispersers selected the closest and the largest population. We showed that mortality can be homogeneous from one program to another while, on the contrary, dispersal is highly dependent on the matrix of established populations. Dispersal behavior is thus of major interest for metapopulation restoration and should be taken into account in planning reintroduction designs.     

内质网应激在不同钙水平下对母鼠氟暴露后仔鼠脑海马细胞的作用

为探讨内质网应激在不同饲料钙水平下对母鼠氟暴露后仔鼠脑海马细胞的作用,选用SD雌性大鼠75只,雄性大鼠25只,雌鼠随机分为对照组(DZ)、染氟组(RF)、低钙组(LG)、染氟低钙组(LF)和染氟高钙组(HF)。雌鼠染毒3个月,交配产仔,检测胎鼠与14日龄、28日龄仔鼠脑海马内质网应激伴侣分子BIP、CHOP和CRT蛋白表达水平。结果显示,与DZ组比,胎鼠、14日龄仔鼠RF组、LF组BIP、CHOP和CRT蛋白表达均显著升高,差异具有统计学意义(P 0.01),HF组BIP、CHOP和CRT蛋白表达均升高,差异具有统计学意义(P 0.05),28日龄仔鼠RF组BIP、CHOP蛋白表达显著升高,差异具有统计学意义(P 0.01),CRT蛋白表达升高,差异具有统计学意义(P 0.05),LF组BIP、CHOP和CRT蛋白表达均显著升高,差异具有统计学意义(P 0.01),HF组BIP、CHOP和CRT蛋白表达均显著升高,差异具有统计学意义(P 0.05)。与RF组比,胎鼠与14日龄、28日龄仔鼠LF组BIP、CHOP和CRT蛋白表达水平升高,差异具有统计学意义(P 0.01),胎鼠、14日龄仔鼠HF组BIP、CHOP和CRT蛋白表达水平下降,差异具有统计学意义(P 0.05),28日龄仔鼠BIP、CHOP蛋白表达水平下降,差异具有统计学意义(P 0.05)。研究表明,内质网应激可能参与了母鼠氟暴露致仔鼠脑损伤,高钙饲料可缓解母鼠氟暴露致仔鼠脑海马神经细胞的损伤,低钙饲料则进一步加剧了母鼠氟暴露致仔鼠脑海马神经细胞损伤。