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A case of mosaicism of trisomy 15, with two-thirds of the cells trisomic, was detected at 12 weeks of gestation in amniotic fluid cell cultures obtained with the filtration technique. Ultrasound examination at 13 weeks showed a nodule protruding into the amniotic cavity which was speculated to be remnants of a co-twin, causing the trisomic cell line. At 20 weeks of gestation, a malformation scan (level III) was normal, but supplementary fetal echocardiography revealed a severe cardiac defect (mitral atresia and a ventricular septal defect). Fetal lymphocytes obtained by cordocentesis showed trisomy 15 mosaicism, but only in 5 per cent of the mitoses. After termination, the same percentage of trisomy 15 mosaicism was found in cells from skin and tendon as in the original early amniocentesis. No sign of earlier twinning was found in the placenta or membranes. We conclude that mosaicism in early amniotic fluid obtained by the filter technique in this case reflected the true karyotype accurately and that supplementary echocardiography added significantly to the interpretation of the clinical implications. 相似文献
123.
Michael Beck MD Susanne Braun Wiltrud Coerdt Eberhard Merz Elisabeth Young Adrian C. Sewell 《黑龙江环境通报》1992,12(12):1019-1029
A fetus with mucopolysaccharidosis type IV A (Morquio type A) is described. The family had one affected child exhibiting symptoms of classical Morquio A disease, and late in the subsequent pregnancy prenatal diagnosis was requested. At 23 weeks' gestation, moderate ascites was detected by detailed ultrasound scan and keratan sulphate was found in the amniotic fluid. The pregnancy was terminated by prostaglandin induction and the diagnosis of mucopolysaccharidosis type IV A was confirmed by demonstration of a deficiency of N-acetylgalactosamine-6-sulphate (GalNac-6-S) sulphatase in cultured amniotic cells and in post-mortem fibroblast cultures. The activities of β-galactosidase and arylsulphatase A were normal, ruling out Morquio disease type B and multiple sulphatase deficiency. These results indicate that mucopolysaccharidosis IV A (a disease that predominantly affects the skeletal system) may produce ascites in the fetus to such an extent that it can be detected by ultrasound. 相似文献
124.
Most marine fishes undergo a pelagic larval phase, the early life history stage that is often associated with a high rate
of mortality due to starvation and predation. We present the first study that examines the effects of prey swimming behavior
on prey-capture kinematics in marine fish larvae. Using a digital high-speed video camera, we recorded the swimming velocity
of zooplankton prey (Artemia franciscana, Brachionus rotundiformis, a ciliate species, and two species of copepods) and the feeding behavior of red drum (Sciaenops ocellatus) larvae. From the video recordings we measured: (1) zooplankton swimming velocity in the absence of a red drum larva; (2)
zooplankton swimming velocity in the presence of a red drum larva; and (3) the excursion and timing of key kinematic events
during prey capture in red drum larvae. Two-way ANOVA revealed that: (1) swimming velocity varied among zooplankton prey;
and (2) all zooplankton prey, except rotifers and ciliates, increased their swimming velocity in the presence of a red drum
larva. The kinematics of prey capture differed between two developmental stages in S. ocellatus larvae. Hyoid-stage larvae (3–14 days old) fed on slow swimming B. rotundiformis (rotifers) while hyoid-opercular stage larvae (15 days and older) ate fast moving A. franciscana. Hyoid-opercular stage red drum larvae had a larger gape, hyoid depression and lower jaw angle, and a longer gape cycle duration
relative to their hyoid-stage conspecifics. Interestingly, the feeding repertoire within either stage of red drum development
was not affected by prey type. Knowledge of the direct relationship between fish larvae and their prey aids in our understanding
of optimal foraging strategies and of the sources of mortality in marine fish larvae. 相似文献
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Rodrigo Villarroel Walker Michael Bruce Beck Jim W. Hall 《Frontiers of Environmental Science & Engineering》2012,6(5):596-611
Driven by considerations of sustainability, it has become increasingly difficult over the past 15?C20 years ?? at least intellectually ?? to separate out the water infrastructure and water metabolism of cities from their intimately inter-related nutrient and energy metabolisms. Much of the focus of this difficulty settles on the wastewater component of the city??s water infrastructure and its associated fluxes of nutrients (N, P, C, and so on). Indeed, notwithstanding the massive volumes of these materials flowing into and out of the city, the notion of an urban nutrient infrastructure is conspicuous by its absence. Likewise, we do not tend to discuss, or conduct research into, ??soilshed?? agencies, or soilshed management, or Integrated Nutrient Resources Management (as opposed to its most familiar companion, Integrated Water Resources Management, or IWRM). The paper summarizes some of the benefits (and challenges) deriving from adopting this broader, multi-sectoral ??systems?? perspective on addressing water-nutrient-energy systems in city-watershed settings. Such a perspective resonates with the growing interest in broader policy circles in what is called the ??water-food-energy security nexus??. The benefits and challenges of our Multi-sectoral Systems Analysis (MSA) are illustrated through computational results from two primary case studies: Atlanta, Georgia, USA; and London, UK. Since our work is part of the International Network on Cities as Forces for Good in the Environment (CFG; see www.cfgnet.org), in which other case studies are currently being initiated ?? for example, on Kathmandu, Nepal ?? we close by reflecting upon these issues of water-nutrient-energy systems in three urban settings with quite different styles and speeds of development. 相似文献
128.
Degradation of polycyclic aromatic hydrocarbons (PAHs) in an aged coal tar contaminated soil under in-vessel composting conditions 总被引:2,自引:0,他引:2
Antizar-Ladislao B Lopez-Real J Beck AJ 《Environmental pollution (Barking, Essex : 1987)》2006,141(3):459-468
In-vessel composting of polycyclic aromatic hydrocarbons (PAHs) present in contaminated soil from a manufactured gas plant site was investigated over 98 days using laboratory-scale in-vessel composting reactors. The composting reactors were operated at 18 different operational conditions using a 3-factor factorial design with three temperatures (T, 38 degrees C, 55 degrees C and 70 degrees C), four soil to green waste ratios (S:GW, 0.6:1, 0.7:1, 0.8:1 and 0.9:1 on a dry weight basis) and three moisture contents (MC, 40%, 60% and 80%). PAH losses followed first order kinetics reaching 0.015 day(-1) at optimal operational conditions. A factor analysis of the 18 different operational conditions under investigation indicated that the optimal operational conditions for degradation of PAHs occurred at MC 60%, S:GW 0.8:1 and T 38 degrees C. Thus, it is recommended to maintain operational conditions during in-vessel composting of PAH-solid waste close to these values. 相似文献
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130.
Jull AJ Burr GS Beck JW Donahue DJ Biddulph D Hatheway AL Lange TE McHargue LR 《Journal of environmental radioactivity》2003,69(1-2):3-19
There are many diverse uses of accelerator mass spectrometry (AMS). Carbon-14 studies at our laboratory include much research related to paleoclimate, both with 14C as a tracer of past changes in environmental conditions as observed in corals, marine sediments and many terrestrial records. Terrestrial records such as forest fires can also show the influence of oceanic oscillations, whether they are short-term such as ENSO, or on the millennial time scale. In tracer applications, we have developed the use of 129I as well as 14C as tracers for nuclear pollution studies around radioactive waste dump sites, in collaboration with IAEA. We discuss some applications carried out in Tucson for several of these fields and hope to give some idea of the breadth of these studies. 相似文献