Environmental Science and Pollution Research - One of the most widely used antibiotics is amoxicillin (AMX), which is the most widely used in humans and animals, but it is discharged metabolically... 相似文献
Gene expression can be modified in people who are chronically exposed to high concentrations of heavy metals. The soil surrounding the Ventanas Industrial Complex, located on the coastal zone of Puchuncaví and Quintero townships (Chile), contain heavy metal concentrations (As, Cu, Pb, Zn, among others) that far exceed international standards. The aim of this study was to determine the potential association of the heavy metals in soils, especially arsenic, with the status of methylation of four tumor suppressor genes in permanent residents in those townships. To study the methylation status in genes p53, p16, APC, and RASSF1A, we took blood samples from adults living in areas near the industrial complex for at least 5 years and compared it to blood samples from adults living in areas with normal heavy metal concentrations of soils. Results indicated that inhabitants of an area with high levels of heavy metals in soil have a significantly higher proportion of methylation in the promoter region of the p53 tumor suppressor gene compared with control areas (p-value: 0.0035). This is the first study to consider associations between heavy metal exposure in humans and aberrant DNA methylation in Chile. Our results suggest more research to support consistent decision-making on processes of environmental remediation or prevention of exposure.
Environmental Science and Pollution Research - Microplastics (MPs) correspond to plastics between 0.1 μm and 5 mm in diameter, and these can be intentionally manufactured to be microscopic or... 相似文献
Environmental Science and Pollution Research - The protective mechanism of extracellular polymeric substance (EPS) secreted by a harmful cyanobacteria against tannins allelochemicals was explored... 相似文献
Journal of Polymers and the Environment - Biopolymer-based films are hydrophilic biodegradable matrices that exhibit poor water vapour barrier. Ideally, water vapour permeability does not depend on... 相似文献