The Hyper-Envelope Modeling Interface (HEMI): A Novel Approach Illustrated Through Predicting Tamarisk (Tamarix spp.) Habitat in the Western USA

Habitat suitability maps are commonly created by modeling a species’ environmental niche from occurrences and environmental characteristics. Here, we introduce the hyper-envelope modeling interface (HEMI), providing a new method for creating habitat suitability models using Bezier surfaces to model a species niche in environmental space. HEMI allows modeled surfaces to be visualized and edited in environmental space based on expert knowledge and does not require absence points for model development. The modeled surfaces require relatively few parameters compared to similar modeling approaches and may produce models that better match ecological niche theory. As a case study, we modeled the invasive species tamarisk (Tamarix spp.) in the western USA. We compare results from HEMI with those from existing similar modeling approaches (including BioClim, BioMapper, and Maxent). We used synthetic surfaces to create visualizations of the various models in environmental space and used modified area under the curve (AUC) statistic and akaike information criterion (AIC) as measures of model performance. We show that HEMI produced slightly better AUC values, except for Maxent and better AIC values overall. HEMI created a model with only ten parameters while Maxent produced a model with over 100 and BioClim used only eight. Additionally, HEMI allowed visualization and editing of the model in environmental space to develop alternative potential habitat scenarios. The use of Bezier surfaces can provide simple models that match our expectations of biological niche models and, at least in some cases, out-perform more complex approaches.     

Cell-free DNA screening in twin pregnancies: A more accurate and reliable screening tool

Objective

Outcome data from cell-free DNA (cfDNA) screening in twin gestations are limited. This study adds an appreciable number of confirmed outcomes to the literature, and assesses performance of cfDNA screening in twins over a 4.5-year period at one large clinical laboratory.

Method

Prenatal cytogenetic and SNP microarray results were cross-referenced with cfDNA results for twin pregnancies, yielding 422 matched cases. Using diagnostic results as truth, performance of cfDNA screening in this population was assessed.

Results

Of the 422 twin pregnancies with both cfDNA and diagnostic results, 3 specimens failed amniocyte analysis, and 48 samples (11.5%) were nonreportable from the initial cfDNA draw. Analysis of the 371 reportable samples demonstrated a collective sensitivity of 98.7% and specificity of 93.2% for trisomies 21/18/13. Positive predictive values (PPVs) in this study population, which is enriched for aneuploidy, were 78.7%, 84.6%, and 66.7% for trisomy 21, 18, and 13, respectively.

Conclusion

CfDNA screening in a cohort of twin pregnancies with matched diagnostic results showed superior performance compared to traditional serum biochemical screening in twins. This study adds to a growing body of evidence suggesting that cfDNA is an accurate and reliable screening tool for the major trisomies in twin pregnancies.

     

Robust prediction of chatter stability in milling based on the analytical chatter stability

A major obstacle that limits the productivity in machining operations is the presence of machine tool chatter. Machining is a dynamic process and chatter behavior depends upon a number of different aspects including spindle speeds, material properties, tool geometry, and even the location of tool respect to the rest of machine. Many of the traditional models used to predict chatter stability lobes assume that parameters such as natural frequency, stiffness, and cutting coefficients remain constant. In reality, these parameters vary and they affect the chatter stability. The uncertainty in these parameters can be taken into consideration by employing the robust stability theory into a two degree of freedom milling model. Utilizing the Edge theorem and the Zero Exclusion condition, a robust chatter stability model, based on the analytical chatter stability milling model, is developed. This improves the reliability compared to the projected pseudo single degree of freedom model. The method is verified experimentally for milling operations while considering a changing natural frequency and cutting coefficient.     

Dislocating identity: Desegregation and the transformation of place

Whatever other changes it engenders, desegregation invariably produces a re-organization of space and place, a fact whose implications the psychological literature on the process has generally disregarded. The present article begins to address this gap. Drawing on research on place–identity processes, we argue that desegregation may alter not only the relationship between self and other, but also the relationship between self and place. As such, it may be experienced as a form of dislocation: an event that undermines shared constructions of place and the forms of located subjectivity they sustain. In order to develop this idea, we analyse a series of interviews conducted with holiday-makers on a formerly white but now multiracial beach in South Africa. The analysis demonstrates how white respondents’ stories of desegregation evince an abiding concern with the loss of place, manifest in terms of an erosion of a sense of place belonging, attachment and familiarity and an undermining of the beach's capacity to act as a restorative environment of the self. The implications of such accounts for understanding personal and ideological resistance to desegregation are explored. The paper concludes by arguing that this problem provides an opportunity to conjoin environmental and social psychological work.     

The effects of long-term unemployment on attitudes to employment

This paper is concerned with whether long-term unemployment (6-24 months) affects people's attitudes to employment once they have found a new job. One hundred and forty men aged 25-40 were asked whether they felt various aspects of employment (e.g. job security, pay) are more important to them as a result of being unemployed. The effects of mental well-being when unemployed on attitudes to employment are explored. Unemployment is reported to have made most aspects of employment more important to people. Those whose mental health was worst when unemployed report that job security is most important to them.     

Differential fate of erythromycin and beta-lactam resistance genes from swine lagoon waste under different aquatic conditions

The attenuation and fate of erythromycin-resistance-methylase (erm) and extended-spectrum beta-lactamse (bla) genes were quantified over time in aquatic systems by adding 20-L swine waste to 11,300-L outdoor mesocosms that simulated receiving water conditions below intensive agricultural operations. The units were prepared with two different light-exposure scenarios and included artificial substrates to assess gene movement into biofilms. Of eleven genes tested, only erm(B), erm(F), bla_SHV and bla_TEM were found in sufficient quantity for monitoring. The genes disappeared rapidly from the water column and first-order water-column disappearance coefficients were calculated. However, detected gene levels became elevated in the biofilms within 2 days, but then disappeared over time. Differences were observed between sunlight and dark treatments and among individual genes, suggesting that ecological and gene-specific factors play roles in the fate of these genes after release into the environment. Ultimately, this information will aid in generating better predictive models for gene fate.