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This work aims at discussing some concepts pertaining to the theory and practice of environmental modelling in view of the results of several model validation exercises performed by the group “Model validation for radionuclide transport in the system watershed-river and in estuaries” of project EMRAS (Environmental Modelling for Radiation Safety) supported by the IAEA (International Atomic Energy Agency). The analyses here performed concern models applied to real scenarios of environmental contamination. In particular, the reasons for the uncertainty of the models and the EBUA (empirically based uncertainty analysis) methodology are discussed. The foundations of multi-model approach in environmental modelling are presented and motivated. An application of EBUA to the results of a multi-model exercise concerning three models aimed at predicting the wash-off of radionuclide deposits from the Pripyat floodplain (Ukraine) was described. Multi-model approach is, definitely, a tool for uncertainty analysis. EBUA offers the opportunity of an evaluation of the uncertainty levels of predictions in multi-model applications. 相似文献
154.
Forty-two samples of building materials commonly used in Italian dwellings were surveyed for natural radioactivity. External (gamma), as defined and used by the European Commission, and internal (alpha) hazard indexes were calculated and radon specific exhalation rate and emanation fraction were measured. The accumulation method, by using the E-PERM electret ion chambers, was employed to determine specific exhalation rates of 222Rn. Several of the materials had hazard indexes that exceeded the European Commission limit values. However, it was evident that limit values for internal hazard indexes set based on Rn emanation should take into account the properties and use of the materials. For example, Rn emanation from basalt and glazed tiles was substantially lower than the Rn emanation from other materials with similar hazard indexes. Clearly there is need for improved guidelines and regulations in this area. 相似文献
155.
Approaches to semi-synthetic minimal cells: a review 总被引:1,自引:0,他引:1
Following is a synthetic review on the minimal living cell, defined as an artificial or a semi-artificial cell having the
minimal and sufficient number of components to be considered alive. We describe concepts and experiments based on these constructions,
and we point out that an operational definition of minimal cell does not define a single species, but rather a broad family
of interrelated cell-like structures. The relevance of these researches, considering that the minimal cell should also correspond
to the early simple cell in the origin of life and early evolution, is also explained. In addition, we present detailed data
in relation to minimal genome, with observations cited by several authors who agree on setting the theoretical full-fledged
minimal genome to a figure between 200 and 300 genes. However, further theoretical assumptions may significantly reduce this
number (i.e. by eliminating ribosomal proteins and by limiting DNA and RNA polymerases to only a few, less specific molecular
species). Generally, the experimental approach to minimal cells consists in utilizing liposomes as cell models and in filling
them with genes/enzymes corresponding to minimal cellular functions. To date, a few research groups have successfully induced
the expression of single proteins, such as the green fluorescence protein, inside liposomes. Here, different approaches are
described and compared. Present constructs are still rather far from the minimal cell, and experimental as well as theoretical
difficulties opposing further reduction of complexity are discussed. While most of these minimal cell constructions may represent
relatively poor imitations of a modern full-fledged cell, further studies will begin precisely from these constructs. In conclusion,
we give a brief outline of the next possible steps on the road map to the minimal cell.
相似文献
Pier Luigi Luisi (Corresponding author)Email: |
Francesca FerriEmail: |
Pasquale StanoEmail: |
156.
Luigi Spezia Susan L. Cooksley Mark J. Brewer David Donnelly Angus Tree 《Environmental and Ecological Statistics》2014,21(3):487-505
The investigation of species distributions in rivers involves data which are inherently sequential and unlikely to be fully independent. To take these characteristics into account, we develop a Bayesian hierarchical model for mapping the distribution of freshwater pearl mussels in the River Dee (Scotland). At the top of the hierarchy the likelihood is used to describe the sequence of sites in which mussels were observed or not. Given that false observations can occur, and that “not observed” means both that the species was not present and that it was not observed, a Markov prior is introduced at the second level of the hierarchy to represent the sequence of sites in which mussels are estimated to occur. The Markov prior allows modelling the spatial dependency between neighbouring sites. A third level in the hierarchy is given by the representation of the transition probabilities of the Markov chain in terms of site-specific explanatory variables, through a logistic regression. The selection of the explanatory variables which influence the Markov process is performed by means of a simulation-based procedure, in the complex case of association between covariates. Four features were found to be associated with reduced chance of finding a local mussel population: tributaries, bridges, dredging, and waste water treatment works. These results complement the results of a previous study, providing new evidence for the causes of the deterioration of a highly threatened species. 相似文献
157.
The paper presents the results of a study on radiological impacts resulting from a zircon sand processing plant located in the North-Eastern part of Italy. Activity concentrations of radionuclides found in materials associated with this industrial process are presented as well as the results of the assessment of the annual effective doses to the workers and the members of the public. Gamma-spectrometric analyses were performed on "raw" sands, end-products, and soils sampled near the plant. Thermoluminescent dosimeters, electric pumps and electret ion chambers were used to measure the external irradiation, the indoor dust concentrations and the radon concentrations, respectively. The ground-level air concentration of radioactive particulate near the plant and the deposition of particulate matter were estimated by a Gaussian model (ISCLT3). Finally, the annual effective doses, calculated as provided for by Directive 96/29/Euratom, were estimated to be 1.7 mSv y(-1) for workers and 4.4 microSv y(-1) for members of the public. 相似文献
158.
159.
Jesus Rodriguez-Manzano Ayalkibet Hundesa Byron Calgua Anna Carratala Carlos Maluquer de Motes Marta Rusiñol Vanessa Moresco Ana Paula Ramos Fernando Martínez-Marca Miquel Calvo Celia Regina Monte Barardi Rosina Girones Sílvia Bofill-Mas 《Food and environmental virology》2014,6(1):31-41
Shellfish complying with European Regulations based on quantification of fecal bacterial indicators (FIB) are introduced into markets; however, information on viruses, more stable than FIB, is not available in the literature. To assess the presence of noroviruses (NoVs) GI and GII and human adenoviruses (HAdV) in domestic and imported mussels and clams (n = 151) their presence was analyzed during winter seasons (2004–2008) in north-west Spanish markets through a routine surveillance system. All samples tested negative for NoV GI and 13 % were positive for NoV GII. The role of HAdV as viral indicator was evaluated in 20 negative and 10 positive NoV GII samples showing an estimated sensitivity and specificity of HAdV to predict the presence of NoV GII of 100 and 74 % (cut-off 0.5). The levels of HAdV and NoVs and the efficiency of decontamination in shellfish depuration plants (SDP) were evaluated analyzing pre- and post-depurated mussels collected in May–June 2010 from three different SDP. There were no statistically significant differences in the prevalence and quantification of HAdV between pre- and post-depurated shellfish and between seawater entering and leaving the depuration systems. Moreover, infectious HAdV were detected in depurated mussels. These results confirm previous studies showing that current controls and depuration treatments limiting the number of FIB do not guarantee the absence of viruses in shellfish. 相似文献
160.
Christian Kuhlicke Annett Steinführer Chloe Begg Chiara Bianchizza Michael Bründl Matthias Buchecker Bruna De Marchi Marina Di Masso Tarditti Corina Höppner Bla? Komac Louis Lemkow Jochen Luther Simon McCarthy Luigi Pellizzoni Ortwin Renn Anna Scolobig Meera Supramaniam Sue Tapsell Gisela Wachinger Gordon Walker Rebecca Whittle Matija Zorn Hazel Faulkner 《Environmental Science & Policy》2011,14(7):804-814
Social capacity building for natural hazards is a topic increasingly gaining relevance not only for so-called developing countries but also for European welfare states which are continuously challenged by the social, economic and ecological impacts of natural hazards. Following an outline of recent governance changes with regard to natural hazards, we develop a heuristic model of social capacity building by taking into account a wide range of existing expertise from different fields of research. Particular attention is paid to social vulnerability and its assessment, as well as to risk communication and risk education as specific strategies of social capacity building. We propose to distinguish between interventionist and participatory approaches, thus enabling for a better understanding of existing practices of social capacity building as well as their particular strengths and weaknesses. By way of conclusion, we encourage more research on social capacity building for natural hazards in the European context which at present is highly diverse and, at least in parts, only poorly investigated. 相似文献