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41.
Mary C. Phelan Ph.D. Robert A. Saul Thompson A. Gailey Jr Steven A. Skinner 《黑龙江环境通报》1995,15(3):274-277
Mosaicism for the Wolf-Hirschhorn syndrome, del(4)(p16), is extremely rare and has not been reported in association with a numerical chromosome abnormality. We report the prenatal diagnosis of mosaic del(4)(p16) and non-mosaic trisomy 21 in a 16-week female fetus. The pregnancy ended in spontaneous abortion at 34 weeks secondary to fetal demise. The fetus had features of both 4p – and trisomy 21. 相似文献
42.
M. Peter Marinkovich MD Guerrino Meneguzzi Robert E. Burgeson Claudine Blanchet-Bardon Karen A. Holbrook Lynne T. Smith Angela M. Christiano Jean-Paul Ortonne 《黑龙江环境通报》1995,15(11):1027-1034
Herlitz junctional epidermolysis bullosa (HJEB) is a severe blistering disorder which usually results in death during infancy. We have previously shown that the anchoring filament protein laminin-5 (kalinin/nicein), which mediates keratinocyte attachment and dermal–epidermal cohesion, is abnormally expressed in individuals with HJEB. Laminin-5 was detected by Western blot analysis in amniotic fluid from 44 consecutive normal secondtrimester control pregnancies, but was undetectable in second-trimester amniotic fluid from four pregnancies with fetuses affected by HJEB. In one case of severe non-Herlitz JEB, laminin-5 was detected in both amniotic fluid and skin. In human amniotic fluid, the laminin-5 a3 subunit was processed to a major 165 kD species and a minor 145 kD species and the β2 subunit was partially processed to 105 kD. Although laminin-5 was covalently associated with laminin-6 (K-laminin) in amniotic membrane, no covalent interaction was detected in amniotic fluid. Laminin-5 from amniotic fluid strongly supported keratinocyte attachment. These results suggest that Western blot analysis of second-trimester amniotic fluid is useful in determining the prenatal diagnosis of HJEB and that laminin-5 may serve a physiologically important function in amniotic fluid. 相似文献
43.
Stickler syndrome is an autosomal dominant disorder of the connective tissue which includes ocular and systemic manifestations. We report on a large kindred in which we were able to demonstrate very tight linkage between the disease and the type II collagen gene (COL2A1) (LOD score 3·91 at θ=0). In a family in which the father and one of his daughters were severely affected, DNA analysis from a chorionic villus sample demonstrated that the fetus possessed the normal allele of COL2A1. Thereafter a normal child was born. 相似文献
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46.
A Simulation of Temporal and Spatial Variations in Carbon at Landscape Level: A Case Study for Lake Abitibi Model Forest in Ontario,Canada 总被引:2,自引:0,他引:2
Xiaolu Zhou Changhui Peng Qing-Lai Dang Jiaxin Chen Sue Parton 《Mitigation and Adaptation Strategies for Global Change》2007,12(4):525-543
Using a case study of the Lake Abitibi Model Forest (LAMF), this study aims to assess the temporal and spatial variability
in carbon storage during 1990–2000, and to present a comprehensive estimation of the carbon budget for LAMF's ecosystems.
As well, it provided the information needed by local forest managers to develop ecological and carbon-based indicators and
monitor the sustainability of forest ecosystems. Temporal and spatial carbon dynamics were simulated at the landscape level
using ecosystem model TRIPLEX1.0 and Geographical Information System (GIS). The simulated net primary productivity (NPP) and
carbon storage in forest biomass and soil were compared with field data and results from other studies for Canada's boreal
forests. The results show that simulated NPP ranged from 3.26 to 3.34 tC ha−1 yr−1 in the 1990s and was consistent with the range measured during the Boreal Ecosystem-Atmosphere Studies (BOREAS) in central
Canada. Modeled NPP was also compared with the estimation from remote sensing data. The density of total above-and belowground
biomass was 125.3, 111.8, and 106.5 tC ha−1 for black spruce, trembling aspen, and jack pine in the LAMF ecosystem, respectively. The total carbon density of forested
land was estimated at 154.4 tC ha−1 with the proportion of 4:6 for total biomass and soil. The analysis of net carbon balance of ecosystem suggested that the
LAMF forest ecosystem was acting as a carbon sink with an allowable harvest in the 1990s. 相似文献
47.
In angiosperms, archesporial cells in the anther primordium undergo meiosis to form haploid pollen, the sole occupants of anther sacs. Anther sacs are held together by a matrix of parenchyma cells, the connective tissue. Cells of the connective tissue are not known to differentiate. We report the differentiation of parenchyma cells in the connective tissue of two Gordonia species into pollen-like structures (described as pseudopollen), which migrate into the anther sacs before dehiscence. Pollen and pseudopollen were distinguishable by morphology and staining. Pollen were tricolpate to spherical while pseudopollen were less rigid and transparent with a ribbed surface. Both types were different in size, shape, staining and surface architecture. The ratio of the number of pseudopollen to pollen was 1:3. During ontogeny in the connective tissue, neither cell division nor tetrad formation was observed and hence pseudopollen were presumed to be diploid. Only normal pollen germinated on a germination medium. Fixed preparations in time seemed to indicate that pseudopollen migrate from the connective tissue into the anther sac. 相似文献
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49.
We have determined the activity of alkaline phosphatase in chorionic villous tissue obtained in the first trimester of pregnancy, in order to obtain the normal range of values as a prerequisite for application to the prenatal diagnosis of the rare bone disease hypophosphatasia. The activities found were a combination of intestinal and liver/bone/kidney types; traces of placental type were present in only one sample. 相似文献
50.
Mitigation and Adaptation Strategies for Global Change - 相似文献