Prenatal detection of monosomy 21 mosaicism

We report a case of chromosomal mosaicism for monosomy 21 revealed in amniotic fluid cell culture. Ultrasound examination at 19 weeks' gestation showed in utero growth retardation and a complex cardiac malformation. A repeated amniocentesis confirmed the presence of monosomy 21 mosaicism. In view of the sonographically detected fetal abnormalities, termination of pregnancy was elected.     

"It's not that simple": A collaborative comparison of sea ice environments, their uses, observed changes, and adaptations in Barrow, Alaska, USA, and Clyde River, Nunavut, Canada

The Arctic environment, including sea ice, is changing. The impacts of these changes to Inuit and I?upiat ways of life vary from place to place, yet there are common themes as well. The study reported here involved an exchange of hunters, Elders, and others from Barrow, Alaska, USA, and Clyde River, Nunavut, Canada, as members of a larger research team that also included visiting scientists. Although the physical environments of Barrow and Clyde River are strikingly different, the uses of the marine environment by residents, including sea ice, had many common elements. In both locations, too, extensive changes have been observed in recent years, forcing local residents to respond in a variety of ways. Although generally in agreement or complementary to one another, scientific and indigenous knowledge of sea ice often reflect different perspectives and emphases. Making generalizations about impacts and responses is challenging and should therefore be approached with caution. Technology provides some potential assistance in adapting to changing sea ice, but by itself, it is insufficient and can sometimes have undesirable consequences. Reliable knowledge that can be applied under changing conditions is essential. Collaborative research and firsthand experience are critical to generating such new knowledge.     

Recovery from blast fishing on coral reefs: a tale of two scales.

Dynamite or "blast" fishing is one of the most immediate and destructive threats to coral reefs worldwide. However, little is known about the long-term ecosystem effects of such blasts or the dynamics of recovery. Here, we examine coral reef recovery in the simplest case of acute single blasts of known age, as well as recovery from chronic blasting over greater spatial and temporal scales. Rubble resulting from single blasts slowly stabilized, and craters filled in with surrounding coral and new colonies. After five years, coral cover within craters no longer differed significantly from control plots. In contrast, extensively bombed areas showed no significant recovery over the six years of this study, despite adequate supply of coral larvae. After extensive blasting, the resulting coral rubble shifts in ocean currents, forming unstable "killing fields" for new recruits. While recently tested rehabilitation methods might be feasible on a small scale, human intervention is unlikely to be effective on large spatial scales, highlighting the need for effective management to prevent blast fishing in the first place.     

EVALUATION OF A STREAM AQUIFER ANALYSIS TEST USING ANALYTICAL SOLUTIONS AND FIELD DATA1

ABSTRACT: Considerable advancements have been made in the development of analytical solutions for predicting the effects of pumping wells on adjacent streams and rivers. However, these solutions have not been sufficiently evaluated against field data. The objective of this research is to evaluate the predictive performance of recently proposed analytical solutions for unsteady stream depletion using field data collected during a stream/aquifer analysis test at the Tamarack State Wildlife Area in eastern Colorado. Two primary stream/aquifer interactions exist at the Tamarack site: (1) between the South Platte River and the alluvial aquifer and (2) between a backwater stream and the alluvial aquifer. A pumping test is performed next to the backwater stream channel. Drawdown measured in observation wells is matched to predictions by recently proposed analytical solutions to derive estimates of aquifer and streambed parameters. These estimates are compared to documented aquifer properties and field measured streambed conductivity. The analytical solutions are capable of estimating reasonable values of both aquifer and streambed parameters with one solution capable of simultaneously estimating delayed aquifer yield and stream flow recharge. However, for long term water management, it is reasonable to use simplified analytical solutions not concerned with early‐time delayed yield effects. For this site, changes in the water level in the stream during the test and a varying water level profile at the beginning of the pumping test influence the application of the analytical solutions.