Targeting natural products against SARS-CoV-2

Environmental Science and Pollution Research - The human coronavirus disease (COVID-19) pandemic is caused by a novel coronavirus; the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2)....     

Anticipated pharmacological role of Aviptadil on COVID-19

Environmental Science and Pollution Research - Vasoactive intestinal peptide (VIP) is a neuropeptide that is produced by the lymphoid cells and plays a major role in immunological functions for...     

Exploration of potential role of Rho GTPase in nicotine dependence-induced withdrawal syndrome in mice

Environmental Science and Pollution Research - The RhoA gene showed an important genotypic association with nicotine dependence and smoking initiation. The current study aims to investigate the...     

In-silico screening of naturally derived phytochemicals against SARS-CoV Main protease

Environmental Science and Pollution Research - Coronavirus disease 2019 (COVID-19) is a rapidly growing pandemic that requires urgent therapeutic intervention. Finding potential anti COVID-19 drugs...     

Gathering new knowledge from existing monitoring dataset of Campania marine coastal area (Southern Italy)

Environmental Science and Pollution Research - In this study we propose, a multi-step strategy of selection and characterization of long-term dataset of contaminant concentrations in different...     

Multi-criteria analysis for improving strategic environmental assessment of water programmes. A case study in semi-arid region of Brazil

Multi-criteria analysis (MCA) is a family of decision-making tools that can be used in strategic environmental assessment (SEA) procedures to ensure that environmental, social and economic aspects are integrated into the design of human development strategies and planning, in order to increase the contribution of the environment and natural resources to poverty reduction. The aim of this paper is to highlight the contribution of a particular multi-criteria technique, the analytic hierarchy process (AHP), in two stages of the SEA procedure applied to water programmes in developing countries: the comparison of alternatives and monitoring. This proposal was validated through its application to a case study in Brazilian semi-arid region. The objective was to select and subsequently monitor the most appropriate programme for safe water availability. On the basis of the SEA results, a project was identified and implemented with successful results. In terms of comparisons of alternatives, AHP meets the requirements of human development programme assessment, including the importance of simplicity, a multidisciplinary and flexible approach, and a focus on the beneficiaries' concerns. With respect to monitoring, the study shows that AHP contributes to SEA by identifying the most appropriate indicators, in order to control the impacts of a project.     

The ameliorative effects of ceftriaxone and vitamin E against cisplatin-induced nephrotoxicity

Environmental Science and Pollution Research - Nephrotoxicity is a common adverse effect of treatment with cisplatin (CDDP). This study was performed to evaluate the antioxidant and...