Modelling of pharmaceutical residues in Australian sewage by quantities of use and fugacity calculations

A conceptual model is presented for determining which currently prescribed pharmaceutical compounds are most likely to be found in sewage, and for estimating their concentrations, both in raw sewage and after successive stages of secondary sewage treatment. A ranking of the "top-50" pharmaceutical compounds (by total mass dispensed) in Australia over the 1998 calendar year was prepared. Information on the excretion ratios and some metabolites of the pharmaceuticals enabled prediction of the overall rates of excretion into Australian sewage. Mass-balance and fugacity modelling, applied to sewage generation and to a sewage treatment plant, allowed calculation of predicted concentrations of the compounds in raw, primary and secondary treated sewage effluents. Twenty nine of the modelled pharmaceutical residuals were predicted to be present in raw sewage influent at concentrations of 1 microgl(-1) or greater. Twenty of the compounds were predicted to remain in secondary effluent at concentrations of 1 microgl(-1) or greater.     

液相飞行时间质谱(LC/MSD TOF)和液相色谱/离子阱质谱(LC/MSD Trap)测定色拉蔬菜中的氯烟碱类杀虫剂

本工作考察了液相色谱／飞行时间质谱检测器(LC／MSDTOF)和液相／离子阱质谱检测器(LC／MSD Trap)联用技术分析一些氯烟碱类杀虫剂的可行性．杀虫剂包括：啶虫咪(acetamiprid)，吡虫啉(imidacloprid)和噻虫啉(thiacloprid)．色拉蔬菜有四种：番茄、辣椒、莴苣和黄瓜．本文介绍的内容包括三种氯烟碱类杀虫剂的LC／MSDTOF和LC／MSD Trap质谱，TOF获得的实验分子式和四种蔬菜基质中氯烟碱类杀虫剂的MS／MS碎片离子．同时也将详细介绍样品制备程序以及色拉蔬菜中杀虫剂的回收、最低检测限(MDL)的质谱质量、线性，使用TOF和Trap对纯溶剂和四种蔬菜提取物中杀虫剂的定量分析．给出了来自市场的实际色拉蔬菜样品中杀虫剂的分析结果．     

PARAMETER DETERMINATION FOR THE MUSKINGUM-CUNGE FLOOD ROUTING METHOD1

ABSTRACT: The proportionality coefficient, K, and the weighing parameter, X, required for the Muskingum-Cunge Flood Routing Method are dependent on the hydraulic characteristics of the channel and the dynamic characteristic of the flood wave. This work focuses on the determination of the Muskingum-Cunge Flood Routing Method parameters for streams where measured hydrographs are not available (i.e., ungaged streams) with floods that stay within the channel banks. In the present work, a gaged creek was used and a dynamic wave was routed to test the reliability of the parameters determined through the Schaefer and Stevens technique (Schaefer and Stevens, 1978). The predicted outflow hydrographs are compared to the hydrographs obtained for the same stream determined with the Muskingum Routing option of the HEC-1 program. Cypress Creek in Harris County, Texas, was the model for this work; and the corresponding data were extracted from the Grant Road and Westfield, Texas, USGS gaging stations.     

Small female rib cage fracture in frontal sled tests

Objectives: The 2 objectives of this study are to (1) examine the rib and sternal fractures sustained by small stature elderly females in simulated frontal crashes and (2) determine how the findings are characterized by prior knowledge and field data.

Methods: A test series was conducted to evaluate the response of 5 elderly (average age 76 years) female postmortem human subjects (PMHS), similar in mass and size to a 5th percentile female, in 30 km/h frontal sled tests. The subjects were restrained on a rigid planar seat by bilateral rigid knee bolsters, pelvic blocks, and a custom force-limited 3-point shoulder and lap belt. Posttest subject injury assessment included identifying rib cage fractures by means of a radiologist read of a posttest computed tomography (CT) and an autopsy. The data from a motion capture camera system were processed to provide chest deflection, defined as the movement of the sternum relative to the spine at the level of T8.

?A complementary field data investigation involved querying the NASS-CDS database over the years 1997–2012. The targeted cases involved belted front seat small female passenger vehicle occupants over 40 years old who were injured in 25 to 35 km/h delta-V frontal crashes (11 to 1 o'clock).

Results: Peak upper shoulder belt tension averaged 1,970 N (SD = 140 N) in the sled tests. For all subjects, the peak x-axis deflection was recorded at the sternum with an average of ?44.5 mm or 25% of chest depth. The thoracic injury severity based on the number and distribution of rib fractures yielded 4 subjects coded as Abbreviated Injury Scale (AIS) 3 (serious) and one as AIS 5 (critical). The NASS-CDS field data investigation of small females identified 205 occupants who met the search criteria. Rib fractures were reported for 2.7% of the female occupants.

Conclusions: The small elderly test subjects sustained a higher number of rib cage fractures than expected in what was intended to be a minimally injurious frontal crash test condition. Neither field studies nor prior laboratory frontal sled tests conducted with 50th percentile male PMHS predicted the injury severity observed. Although this was a limited study, the results justify further exploration of the risk of rib cage injury for small elderly female occupants.     

A field test of the Bruce effect in the monogamous prairie vole (Microtus ochrogaster)

The Bruce effect is a widely studied reproductive phenomenon in rodents in which exposure of pregnant females to unknown males causes termination of the current pregnancy. The Bruce effect has been reported from numerous studies in the laboratory, and one field study with the promiscuous gray-tailed vole, Microtus canicaudus, failed to support it. We conducted a field study with the monogamous prairie vole, M. ochrogaster, to determine if complete replacement of the male population every 10-14 days affected pregnancy and juvenile recruitment. The mean days to first parturition for control and treatment females were 36.8 and 44.4 days. Fifty-five percent of control females and 33% of treatment females conceived within the first 14 days of the study. All control females and 79% of treatment females successfully delivered at least one litter. These differences between treatment and control populations provide minimal support for the Bruce effect when compared with results from laboratory studies. Nulliparous females may have experienced some pregnancy disruption, but not parous females. Removal of mates, rather than exposure to strange males, may have contributed more to the lower reproductive success of treatment females than exposure to strange males. Treatment females, however, had lower juvenile recruitment than controls, which may have been due to infanticide from strange males. Our results are more similar to those of the field study of the gray-tailed vole than predicted, based on laboratory studies of prairie voles.     

Microbial communities and greenhouse gas emissions associated with the biodegradation of specified risk material in compost

Provided that infectious prions (PrP^Sc) are inactivated, composting of specified risk material (SRM) may be a viable alternative to rendering and landfilling. In this study, bacterial and fungal communities as well as greenhouse gas emissions associated with the degradation of SRM were examined in laboratory composters over two 14 day composting cycles. Chicken feathers were mixed into compost to enrich for microbial communities involved in the degradation of keratin and other recalcitrant proteins such as prions. Feathers altered the composition of bacterial and fungal communities primarily during the first cycle. The bacterial genera Saccharomonospora, Thermobifida, Thermoactinomycetaceae, Thiohalospira, Pseudomonas, Actinomadura, and Enterobacter, and the fungal genera Dothideomycetes, Cladosporium, Chaetomium, and Trichaptum were identified as candidates involved in SRM degradation. Feathers increased (P < 0.05) headspace concentrations of CH₄ primarily during the early stages of the first cycle and N₂O during the second. Although inclusion of feathers in compost increases greenhouse gas emissions, it may promote the establishment of microbial communities that are more adept at degrading SRM and recalcitrant proteins such as keratin and PrP^Sc.     

Improving hydrolysis of food waste in a leach bed reactor

This paper examines the rate of degradation of food waste in a leach bed reactor (LBR) under four different operating conditions. The effects of leachate recirculation at a low and high flow rate are examined with and without connection to an upflow anaerobic sludge blanket (UASB). Two dilution rates of the effective volume of the leach bed reactors were investigated: 1 and 6 dilutions per LBR per day. The increase in dilution rate from 1 to 6 improved the destruction of volatile solids without connection to the UASB. However connection to the UASB greatly improved the destruction of volatile solids (by almost 60%) at the low recirculation rate of 1 dilution per day. The increase in volatile solids destruction with connection to the UASB was attributed to an increase in leachate pH and buffering capacity provided by recirculated effluent from the UASB to the leach beds. The destruction of volatile solids for both the low and high dilution rates was similar with connection to the UASB, giving 82% and 88% volatile solids destruction respectively. This suggests that the most efficient leaching condition is 1 dilution per day with connection to the UASB.     

Innovation in risk transfer for natural hazards impacting agriculture

Agricultural income from growing crops is susceptible to a variety of risks—the price of output and the actual amount of output are generally the largest risk variables. This article focuses on yield risk rather than price risk by reviewing innovation in risk transfer for natural hazard risk in agriculture. While many higher-income countries have long-standing crop insurance programs, these programs are not appropriate for lower-income countries. Lower-income countries can ill-afford the subsidies that are used in most multiple peril crop insurance programs throughout the world. Still, lower-income countries have large numbers of small farms increasing the need for agricultural insurance to protect against common problems that create disastrous losses for many individual farm households.     

Sediment budgets and source determinations using fallout Cesium-137 in a semiarid rangeland watershed,Arizona, USA

Analysis of soil redistribution and sediment sources in semiarid and arid watersheds provides information for implementing management practices to improve rangeland conditions and reduce sediment loads to streams. The purpose of this research was to develop sediment budgets and identify potential sediment sources using ¹³⁷Cs and other soil properties in a series of small semiarid subwatersheds on the USDA ARS Walnut Gulch Experimental Watershed near Tombstone, Arizona, USA. Soils were sampled in a grid pattern on two small subwatersheds and along transects associated with soils and geomorphology on six larger subwatersheds. Soil samples were analyzed for ¹³⁷Cs and selected physical and chemical properties (i.e., bulk density, rocks, particle size, soil organic carbon). Suspended sediment samples collected at measuring flume sites on the Walnut Gulch Experimental Watershed were also analyzed for these properties. Soil redistribution measured using ¹³⁷Cs inventories for a small shrub-dominated subwatershed and a small grass-dominated subwatershed found eroding areas in these subwatersheds were losing −5.6 and −3.2 t ha⁻¹ yr⁻¹, respectively; however, a sediment budget for each of these subwatersheds, including depositional areas, found net soil loss to be −4.3 t ha⁻¹ yr⁻¹ from the shrub-dominated subwatershed and −0.1 t ha⁻¹ yr⁻¹ from the grass-dominated subwatershed. Generally, the suspended sediment collected at the flumes of the six other subwatersheds was enriched in silt and clay. Using a mixing model to determine sediment source indicated that shrub-dominated subwatersheds were contributing most of the suspended sediment that was measured at the outlet flume of the Walnut Gulch Experimental Watershed. The two methodologies (sediment budgets and sediment source analyses) indicate that shrub-dominated systems provide more suspended sediment to the stream systems. The sediment budget studies also suggest that sediment yields measured at the outlet of a watershed may be a poor indicator of actual soil redistribution rates within these semiarid watersheds. Management of these semiarid rangelands must consider techniques that will protect grass-dominated areas from shrub invasion to improve rangeland conditions.