Soil, plant, and water, as well as trace elements they contain, can influence human health through the food chain. A survey
was conducted on distributions of trace elements in soils, plants, and drinking water in Rugao County, Jiangsu Province, China,
an agricultural area with a high level of centenarians and nonagenarians. The ratio of people over 90 years old per 100,000
inhabitants (90-rate) based on village (about 4,000 residents in 4 km2) was correlated with trace elements in soil, drinking water, and rice by means of correlation analysis and/or principal component
analysis. Although the average 90-rate in the whole area was as high as 277, the rates were not uniform across the entire
region. The 90-rate in the area of loamy and strongly-developed Anthrosols and Cambosols was about 330, significantly higher
than the 255 in the areas of sandy and strongly-developed Cambosols and of clayey and weakly-developed Cambosols. The concentrations
of available Se, B, Ni, and Mo in soils of the area with the high 90-rate were markedly greater than those in the area with
the low 90-rate. This was demonstrated by highly positive correlations between the 90-rate and available Se (r = 0.33), B (r = 0.21), Ni (r = 0.17) and Mo (r = 0.17) at the p < 0.01 level and high loadings of available Se (0.851), B (0.535), Ni (0.594) and Mo (0.394) in the longevous factor. Similar
relationships between the available elements in soils and elements in water and rice were found. These results suggest that:
(1) the available forms of elements in soil were more crucial to elemental bio-availability in the ecosystem and human health
than total elements in soil; and (2) the element association above might have affected the 90-rate positively and could be
an important environmental geochemical factor influencing the longevity of humans. 相似文献
Herein, we reported the synthesis of well-defined Co_3O_4 nanoarrays(NAs) supported on a monolithic three-dimensional macroporous nickel(Ni) foam substrate for use in highefficiency CO oxidation. The monolithic Co_3O_4 NAs catalysts were obtained through a generic hydrothermal synthesis route with subsequent calcination. By controlling the reaction time,solvent polarity and deposition agent, these Co_3O_4 NAs catalysts exhibited various novel morphologies(single or hybrid arrays), whose physicochemical properties were further characterized by using several analytical techniques. Based on the catalytic and characterization analyses, it was found that the Co_3O_4 NAs-6 catalyst with nanobrush and nanomace arrays displayed enhanced catalytic activity for CO oxidation, achieving an efficient 100% CO oxidation conversion at a gas hourly space velocity(GHSV) 10,000 hr~(-1) and 150°C with longterm stability. Compared with the other Co_3O_4 NAs catalysts, it had the highest abundance of surface-adsorbed oxygen species, excellent low-temperature reducibility and was rich in surface-active sites(Co~(3+)/Co~(2+)= 1.26). 相似文献
Cytotoxicity can be much greater than all other treatments by targeted combination chemotherapy. In this context, we have recognized the use for gastric cancer chemotherapy of multifunctional polymer nanoparticles (PNPs) loaded with Salinomycin (SAL) and Biotin (BT). The encapsulation of BT and SAL anticancer agents co-loaded with polyethylene glycol (PEGs) and nanoparticles of polylactide-co-glycolides (PLGAs) is incompetent due to inadequacy in polymeric biodegradable nanoparticles (PNPs) of the dual antitumor drugs BT and SAL. The morphology of the BT@PNPs, SAL@PNPs and SAL/BT@PNPs, and composition and sizes of the nanoparticles was investigated using a transmission electron microscopy (TEM). In vitro cell death of human gastric cell lines including SGC-791 and NCI-N87 has also been caused by SAL/BT@PNPs. A variety of biochemical stains, for example, AO/EB (Acridine Orange / Ethidium Bromide) and Hoechst, have been used to detect morphological and cell death. The mechanical examination of apoptosis was further tested using the Annexin V-FITC flow cytometry. In overall, SAL/BT@PNPs may be used as a possible instrument for enhanced gastric cancer therapy efficacy in this dual approach to drug delivery.