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We report a case resembling hydrolethalus syndrome in a Chinese family. Fetal polydactyly, syndactyly, encephalocele and cardiac malformation were detected on ultrasound examination at 12 weeks' gestation. Termination of pregnancy was performed, and postmortem examination confirmed the findings. This is the first report of a first-trimester prenatal diagnosis of hydrolethalus syndrome in the Chinese population. Copyright © 2004 John Wiley & Sons, Ltd.  相似文献   
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This paper aims to elaborate new generic DRASTIC aquifer vulnerability maps of the coastal aquifer of Metline-Ras Jebel-Raf Raf (Northeast of Tunisia) using the GIS technique, making the data analyses easier to handle and providing better capabilities of dealing with large spatial data. A similar study was carried out in 1999 in the same aquifer using a method based on the soil water balance equation to determine the net recharge parameter. Unfortunately, the lack of data in the study area made the results unsatisfactory. By applying the Williams and Kissel equation and the Rao relationship, we intend to demonstrate that we could correctly evaluate the net recharge parameter. Moreover, new data related to the aquifer hydraulic conductivity, the soil cover and the vadose zone lithology have become available, and allowed us to elaborate suitable DRASTIC maps.  相似文献   
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Olive mill wastewater (OMW), a by-product of the olive-mill industry, is produced in large amounts in Mediterranean countries. The presence of indigenous phosphate deposits in some countries like Tunisia provides an incentive for direct application or local chemical treatment at low cost to improve the solubility of low reactive phosphate rocks (PRs). The use of naturally occurring low-molecular weight organic acids (LMWOAs) that are present in OMW represents a new perspective in PR research and a possible solution for the recycling of the OMW. The present work was aimed at evaluating, under natural situations (field of olive trees), the effects of agronomic application of OMW (amounts applied: 30, 60 m(3) ha(-1)) with PR (amounts applied: 150 kg ha(-1)) on olive trees soil properties. We measured organic C, nitrogen (N), extractable phosphorus (P), exchangeable calcium (Ca), and exchangeable potassium (K), as well as other properties (pH and electrical conductivity). Our data provide evidence that agronomic application of OMW with PR has important effects on soil properties. Increases in organic C, total N, extractable P and exchangeable potassium (K) were found after the first agronomic application of OMW and PR. These increases were only temporary, following the second agronomic application of OMW and PR, significant reductions were detected in the extractable soil P (19.67 mg kg(-1) in the control soil vs. 8.99 mg kg(-1) in the amended soil). Changes in the extractable soil P could alter plant productivity and plant community structure because shifts in nutriment availability can affect the balance between limiting and non-limiting nutrients.  相似文献   
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It has now been well over 20 years since the North Sea Piper Alpha disaster in 1988. There have been many lessons learned; some documented others just etched in memory. The event chronicled many significant changes in the offshore industry. The emanating point for most sweeping changes has been the Cullen Report and the UK North Sea industry. This paper reviews some of the critical lessons and identifies many ‘secondary’ finer points that constitute important learnings. The paper looks at major changes instigated by step changes in safety criticality. It is argued that the ‘second tier’ modes of failure such as corrosion, materials degradation, environmental cracking, erosion, plant ergonomics, etc. need to be better examined. These mechanisms are dangerous threats to the integrity of deep subsea assets, and it is noted that such root causes of failure as witnessed or predicted have yet to be fully appraised. The authors’ use wide experiences and case histories to highlight such concerns, offering rational fit-for-purpose solutions. The industry disconnections between, urgency to build, knowledge transfer, and management of change, are refocused. Powerful advances in risk-based mechanical, process, materials, and corrosion engineering are emphasized and the use of key performance indicators (KPIs) are reasoned for best life-cycle integrity. To keep up with the pace of growth in the deepwater sector, methods of concurrent and inherently safe design have evolved in a world where the practicalities and costs of modification, repair and retrofit are extremely difficult. Hence getting it right at the outset is paramount. Thus the drive for purposeful investment, at design is more justifiable, than the traditional practice of postponing costs (and problems) to operations. In this way the ominous ‘gray’ zone between the two cost centers is better bridged for reasons of safety and commercial advantage.  相似文献   
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Introduction

The New Zealand Graduated Driver Licensing System (GDLS) is designed to allow novice drivers to gain driving experience under conditions of reduced risk.

Method

To examine the effectiveness of the GDLS, an analysis of how the crash involvement of novice drivers changes as drivers move through the GDLS was undertaken. Crash profiles were created by data matching the New Zealand license and crash databases, covering a time period from 1999-2006.

Results

The crash profiles show that the initial learner period of the GDLS is relatively safe and the time at which novice drivers have the highest rate of crash involvement is during the first few months of solo driving. Analysis using logistic regression also showed an effect of age and gender, with higher crash involvement associated with younger drivers and males. In addition, individuals who gained a full license within 12-18 months of holding a restricted license, due to completion of a time-discount associated educational program, had a higher level of involvement in crashes than individuals who gained a full license after 18 months.

Conclusions

The crash profiles provide an insight into the crash risk associated with different phases of the New Zealand GDLS.

Impact on Industry

Increasing the age at which drivers first begin to solo drive and the removal of the time-discount associated with completion of an educational program should be considered.  相似文献   
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This study reports on a surfactant-based flood for tetrachloroethylene (PCE) removal from a control test cell at the Dover National Test Site. The surfactant formulation (sodium dihexyl sulfosuccinate (Aerosol-MA or AMA), isopropanol and calcium chloride) was able to achieve a high concentration of PCE in swollen micelles (supersolubilization) without vertical PCE migration. The hydraulic system included eight screened wells that were operated in both vertical circulation and line drive configurations. After 10 pore volumes of flushing, the overall PCE removal was 68% (65% of which corresponded to the surfactant flooding alone). In addition, the residual PCE saturation was reduced from 0.7% to 0.2%, and the concentration of PCE in the groundwater was reduced from 37-190 mg/L before the flushing to 7.3 mg/L after flooding. Recycling the surfactant solution reduced the required surfactant mass (and thus cost, and waste) by 90%. Close to 80% of the total PCE removal was obtained during the first five pore volumes which were operated in an upward vertical circulation flow scheme. No free oil phase was observed during the test. Further analysis of multilevel sampler data suggests that most of the trapped oil remaining in the cell was likely localized in secluded regions of the aquifer, which helps explain the lower PCE groundwater concentration after remedial activities. In summary, this field study demonstrated the feasibility of surfactant-enhanced remediation to reduce the mass in the source zone and significantly reduce the PCE aqueous concentration and therefore the risk associated with the contaminant plume.  相似文献   
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