Urinary concentrations of organophosphorus insecticide metabolites in Japanese workers

A recent development in analytical chemistry has enabled us to monitor systemic organophosphorus insecticide (OP) exposure at individual levels. At present, however, limited data are currently available on urinary OP metabolite levels worldwide. The purpose of this study was to assess urinary dialkylphosphate (DAP) concentrations in Japanese workers. Urine samples were collected in both summer and winter from 339 Japanese adults who worked as food distributors (FDs, n = 164), apple farmers (AFs, n = 147) and pest control operators (PCOs, n = 28). DAPs were measured by gas chromatography-mass spectrometry after derivatization with pentafluorobenzylbromide. Dimethylphosphate (DMP), diethylphosphate (DEP), dimethylthiophosphate (DMTP) and diethylthiophosphate (DETP) were detected in the urine of over 87% of the studied populations in both seasons. The geometric mean values of total DAPs (nmol g⁻¹ creatinine), DMP, DMTP, DEP and DETP (μg g⁻¹ creatinine) in summer and winter were 106.7 and 98.3, 7.0 and 3.8, 3.4 and 4.5, 0.8 and 1.5, and 0.3 and 0.2 for the FDs, 440.8 and 197.7, 33.1 and 10.8, 10.1 and 5.8, 4.2 and 4.7 and 1.6 and 0.8 for the AFs, and 473.4 and 284.6, 28.9 and 22.2, 17.6 and 4.6, 3.5 and 4.4, and 0.5 and 0.6 for the PCOs, respectively, thereby revealing significantly higher concentrations in AFs and PCOs groups than in the FDs in both seasons except for winter DMTP. These DAP concentrations were approximately the same or at lower levels compared with those reported in the previous literature. This is one of the first studies to demonstrate urinary DAP concentrations in Japanese adults.     

Mortality of US pentachlorophenol production workers through 2005

A cohort of 2122 US pentachlorophenol (PCP) production workers from four plants in the National Institute for Occupational Safety and Health Dioxin Registry was exposed to PCP and to polychlorinated dibenzo-p-dioxin and dibenzofuran contaminants of PCP production. A subcohort of 720 was also exposed to 2,3,7,8-tetrachlorodibenzodioxin, a contaminant of trichlorophenol (TCP) while using TCP or a TCP derivative. PCP and several production contaminants have been implicated as animal carcinogens. A priori hypotheses were that the cohort would have elevated standardized mortality ratios (SMRs) for aplastic anemia, soft-tissue sarcoma, and non-Hodgkin lymphoma, as suggested by human studies, and for leukemia and liver, adrenal, thyroid, and parathyroid cancer, as suggested by animal studies. From 1940 to 2005 1165 deaths occurred with an overall SMR of 1.01 [95% confidence limits (CI), 0.95-1.07]. Overall cancer mortality (326 deaths, SMR 1.17, CI 1.05-1.31) was in statistically significant excess. There were excess deaths for trachea, bronchus and lung cancers (126 deaths, SMR 1.36, CI 1.13-1.62), non-Hodgkin lymphoma (17 deaths, SMR 1.77, CI 1.03-2.84), chronic obstructive pulmonary disease (63 deaths, SMR 1.38, CI 1.06-1.77), and medical complications (5 deaths, SMR 3.52, CI 1.14-8.22). In race- and sex-specific analyses, white males had increased non-Hodgkin lymphoma mortality (17 deaths, SMR 1.98, CI 1.15-3.17) and males of other races had increased leukemia mortality (four deaths, SMR 4.57, CI 1.25-11.7). The excess of cancers of a priori interest, non-Hodgkin lymphoma and leukemia, provide some support for the carcinogenicity of PCP, however, further studies with more detailed exposure assessment are needed.     

Work-related fatal injuries in parking lots, 1993-2002

PROBLEM: Although parking facilities are a common feature of the landscape in the United States, little is known about their safety. METHOD: A dataset of parking lot fatalities for 1993-2002, created from the Census of Fatal Occupational Injury (CFOI) research file, was analyzed. RESULTS: The most common events in parking lots were contact with objects (15%), pedestrian fatalities (13%), homicides (36%), and suicides (11%). The perpetrators of parking lot fatalities, compared to all workplace homicides, were more likely to be known to the victim. CONCLUSION: The 206 work-related fatalities per year in parking lots present challenges to the safety community. Although much of the risk results from the usage of motor vehicles, violent acts are even more prominent. IMPACT ON INDUSTRY: Because homicides are most prevalent in parking lots, both administrative and environmental measures may lower the risk of homicide. Although difficult to assess, various elements of the design of parking facilities may have an influence on the occurrence of injuries.     

Protecting the planet and its people: how do interventions to promote environmental sustainability and occupational safety and health overlap?

Problem: The challenges of both occupational safety and health and environmental sustainability require large-scale behavior change for meaningful improvements to occur. Environmental sustainability, or the ‘green movement’ has received far more attention recently, and certain strategies and recommendations from interventions designed for promoting pro-environmental behaviors may inform efforts to intervene on critical behaviors for improving occupational safety and health. Method: A survey of the literature regarding behavioral interventions for both environmental sustainability and occupational safety and health was conducted. Several theoretical approaches are reviewed, and successful approaches from each domain are identified, as well as parallel challenges and points for crossover. Recommendations are provided for adapting environmental sustainability intervention approaches for occupational safety and health applications. Impact on Industry: Safety and health leaders may achieve sustainable improvements in worker safety and health by harnessing the momentum of the green movement and adapting successful intervention approaches from the environmental sustainability domain.     

What kinds of injuries do OSHA inspections prevent?

Objective

OSHA's enforcement program is one of the major public efforts to protect American workers. We examine both the scope of injury prevention that inspections can contribute and the types of standards that contribute the most.

Methods

We linked Pennsylvania Department of Labor and Industry files for lost-time injuries and employment to calculate injury rates for 1998-2005 for all single-establishment manufacturing firms. We linked these to OSHA inspection records.

Results

Inspections with penalties did affect injury types unrelated to standards as well as those related. We also found again that citations for violations of the standard requiring personal protective equipment had the largest impact on preventing injuries.

Impact on Industry

Programs requiring protective equipment use deserve added attention from consultants and inspectors. In addition, some inspections spur managers to undertake safety measures that go beyond compliance with standards.     

Occupational risk from static magnetic fields of MRI scanners

The health care staff operating magnetic resonance imaging (MRI) scanners are exposed to static magnetic field of significant spatial heterogenity and high level of flux density—usually existing permanently during the shift. The personnel can also be exposed to pulses of magnetic field of high rate of rise/fall, so-called gradient fields, which exist only during examination of patients. The level of workers’ exposure depends both on the type of the magnet and on the ergonomical characteristic of design of the particular MRI scanner. This paper presents the current state of the art on occupational exposure to static magnetic field health effects, gaps in scientific data, MRI workers’ exposure characteristics, research needs, and suggestions for the exposure assessment protocol for future investigations.     

Prevalence of low back pain in three occupational groups in Shanghai, People's Republic of China

PROBLEM: Low back pain (LBP) is one of the most prevalent work-related conditions affecting employed populations in developed countries, yet little is known about this condition among the world's largest, single-nation labor force: The People's Republic of China. METHOD: This is a cross-sectional study of the prevalence of low back pain (LBP) among garment workers, battery/kiln workers, and teachers in Shanghai, People's Republic of China. Data were collected by personal interview and physical examination at six work sites. The overall response rate was 78%. RESULTS: The overall (N=383) self-reported annual prevalence of LBP symptoms lasting 24 hours or more was 50%. Garment workers had a higher annual prevalence of LBP (74%) than teachers (40%), prevalence ratio (PR=1.9, 95% CI=1.4-2.4). DISCUSSION: The overall annual prevalence of self-reported LBP (50%) was higher than that reported among 50 other Chinese employed study populations (30%). Healthy worker effects may have limited the conclusions from this cross-sectional study. SUMMARY: These results suggest that LBP is a prevalent condition in Chinese workers and that more work should be done to estimate its impact on the Chinese workforce. The findings for garment workers were consistent with increased risk of LBP among persons doing work in fixed, sedentary postures.     

High visibility safety apparel and nighttime conspicuity of pedestrians in work zones

PROBLEM: Every year numerous occupational fatalities result from pedestrians being struck by motor vehicles intruding into work zones. METHOD: Attributes of retroreflective personal safety garments on pedestrian conspicuity at night were assessed in a field study. Using instrumented vehicles on a closed track, participants drove through simulated work zones attempting to detect pedestrians located in the work zones. RESULTS: Configuration of the retroreflective trim, trim color, placement in the work zone, and driver age significantly affected pedestrian conspicuity. Intensity and the amount of retroreflective trim did not. DISCUSSION: Personal safety garments incorporating retroreflective trim significantly improve pedestrian conspicuity in work zones. SUMMARY: The results emphasize the importance of retroreflective trim on personal safety garments, particularly if the trim is located on garment sleeves. IMPACT ON INDUSTRY: We examine the design attributes that contribute to making a personal safety garment conspicuous. The results have implications regarding preferred garment designs, industry standards, and service life of personal safety garments.     

The relationship between employees' perceptions of safety and organizational culture

PROBLEM: With limited resources to help reduce occupational injuries, companies struggle with how to best focus these resources to achieve the greatest reduction in injuries for the optimal cost. Safety culture has been identified as a critical factor that sets the tone for importance of safety within an organization. METHOD: An employee safety perception survey was conducted, and injury data were collected over a 45-month period from a large ready-mix concrete producer located in the southwest region of the United States. RESULTS: The results of this preliminary study suggest that the reductions in injuries experienced at the company locations was strongly impacted by the positive employee perceptions on several key factors. Management's commitment to safety was the factor with the greatest positive perception by employees taking the survey. DISCUSSION: This study was set up as a pilot project and did not unitize an experimental design. That weakness reduces the strength of these findings but adds to the importance of expanding the pilot project with an appropriate experimental design. SUMMARY: Management leadership has been identified, along with several other factors, to influence employee perceptions of the safety management system. Those perceptions, in turn, appear to influence employee decisions that relate to at-risk behaviors and decisions on the job. IMPACT ON INDUSTRY: The results suggest that employee perceptions of the safety system are related to management's commitment to safety, which, in turn, appear to be related to injury rates. Management should focus on how to best leverage these key factors to more positively impact injury rates within their companies.     

职业安全卫生管理体系(OHSMS)第一讲 OHSMS的起源

职业安全卫生管理体系(简称OHSMS),是完善企业职业安全卫生管理,保证企业职业安全卫生绩效持续改进的科学管理模式。国家经贸委1999年10月发布了《职业安全卫生管理试行标准》后,如何实施和建立职业安全卫生管理体系受到社会和企业的普遍重视与关注。 本系列讲座主要论述：OHSMS的起源、发展与意义;OHSMS的基本概念与理论;OHSMS的基本内容、结构与要素;如何建立和实施OHSMS;如何通过OHSMS的评审和认证等。