Mortality of US pentachlorophenol production workers through 2005

A cohort of 2122 US pentachlorophenol (PCP) production workers from four plants in the National Institute for Occupational Safety and Health Dioxin Registry was exposed to PCP and to polychlorinated dibenzo-p-dioxin and dibenzofuran contaminants of PCP production. A subcohort of 720 was also exposed to 2,3,7,8-tetrachlorodibenzodioxin, a contaminant of trichlorophenol (TCP) while using TCP or a TCP derivative. PCP and several production contaminants have been implicated as animal carcinogens. A priori hypotheses were that the cohort would have elevated standardized mortality ratios (SMRs) for aplastic anemia, soft-tissue sarcoma, and non-Hodgkin lymphoma, as suggested by human studies, and for leukemia and liver, adrenal, thyroid, and parathyroid cancer, as suggested by animal studies. From 1940 to 2005 1165 deaths occurred with an overall SMR of 1.01 [95% confidence limits (CI), 0.95-1.07]. Overall cancer mortality (326 deaths, SMR 1.17, CI 1.05-1.31) was in statistically significant excess. There were excess deaths for trachea, bronchus and lung cancers (126 deaths, SMR 1.36, CI 1.13-1.62), non-Hodgkin lymphoma (17 deaths, SMR 1.77, CI 1.03-2.84), chronic obstructive pulmonary disease (63 deaths, SMR 1.38, CI 1.06-1.77), and medical complications (5 deaths, SMR 3.52, CI 1.14-8.22). In race- and sex-specific analyses, white males had increased non-Hodgkin lymphoma mortality (17 deaths, SMR 1.98, CI 1.15-3.17) and males of other races had increased leukemia mortality (four deaths, SMR 4.57, CI 1.25-11.7). The excess of cancers of a priori interest, non-Hodgkin lymphoma and leukemia, provide some support for the carcinogenicity of PCP, however, further studies with more detailed exposure assessment are needed.     

Urinary concentrations of organophosphorus insecticide metabolites in Japanese workers

A recent development in analytical chemistry has enabled us to monitor systemic organophosphorus insecticide (OP) exposure at individual levels. At present, however, limited data are currently available on urinary OP metabolite levels worldwide. The purpose of this study was to assess urinary dialkylphosphate (DAP) concentrations in Japanese workers. Urine samples were collected in both summer and winter from 339 Japanese adults who worked as food distributors (FDs, n = 164), apple farmers (AFs, n = 147) and pest control operators (PCOs, n = 28). DAPs were measured by gas chromatography-mass spectrometry after derivatization with pentafluorobenzylbromide. Dimethylphosphate (DMP), diethylphosphate (DEP), dimethylthiophosphate (DMTP) and diethylthiophosphate (DETP) were detected in the urine of over 87% of the studied populations in both seasons. The geometric mean values of total DAPs (nmol g⁻¹ creatinine), DMP, DMTP, DEP and DETP (μg g⁻¹ creatinine) in summer and winter were 106.7 and 98.3, 7.0 and 3.8, 3.4 and 4.5, 0.8 and 1.5, and 0.3 and 0.2 for the FDs, 440.8 and 197.7, 33.1 and 10.8, 10.1 and 5.8, 4.2 and 4.7 and 1.6 and 0.8 for the AFs, and 473.4 and 284.6, 28.9 and 22.2, 17.6 and 4.6, 3.5 and 4.4, and 0.5 and 0.6 for the PCOs, respectively, thereby revealing significantly higher concentrations in AFs and PCOs groups than in the FDs in both seasons except for winter DMTP. These DAP concentrations were approximately the same or at lower levels compared with those reported in the previous literature. This is one of the first studies to demonstrate urinary DAP concentrations in Japanese adults.     

Low dose effects and non-monotonic dose responses for endocrine active chemicals: Science to practice workshop: Workshop summary

A workshop was held in Berlin September 12–14th 2012 to assess the state of the science of the data supporting low dose effects and non-monotonic dose responses (“low dose hypothesis”) for chemicals with endocrine activity (endocrine disrupting chemicals or EDCs). This workshop consisted of lectures to present the current state of the science of EDC action and also the risk assessment process. These lectures were followed by breakout sessions to integrate scientists from various backgrounds to discuss in an open and unbiased manner the data supporting the “low dose hypothesis”. While no consensus was reached the robust discussions were helpful to inform both basic scientists and risk assessors on all the issues. There were a number of important ideas developed to help continue the discussion and improve communication over the next few years.     

对当前安全工作与人才培养的探讨

通过对当今安全工作和人才培养的现状进行分析和讨论，提出有关对策和办法。以促使安全工作上一个新台阶，保障企业安全生产，促进国民经济迅猛发展。     

关于加强企业职业卫生与健康教育工作的实践和思考

通过对职业卫生与健康教育多方面的论述,指出：职业卫生与健康教育是企业科学管理体系的重要组成部分;强化职业卫生意识宣教,加强职业健康教育组织与管理,是控制或消除职业危害因素,保障职工身心健康,促进企业健康发展的重要动力因素。提出了企业加强职业卫生与健康教育工作的对策和途径。     

对乡镇企业职工的职业安全卫生知识、态度、行为的调查

从对某市部分乡镇企业职工的职业安全卫生知识、态度、行为所进行的调查看,不同状况的人群对职业安全卫生知识、态度、习惯有显著性差异。为此,提示职业安全卫生监督管理部门及企业的有关职能部门在职工的职业安全卫生教育中,要加强对文化程度低、年轻、工龄较短的职工的教育,并采用形式多样化手段。另外,职业安全监督管理部门还要加强监督外资企业做好职工的职业安全卫生教育。从职工对职业安全卫生的态度及行为结果看,提出在进行职业安全卫生教育时,要有针对性。不仅要给职工配备劳保用品,更重要的是监督职工经常和正确地使用劳保用品,并养成良好的卫生习惯     

Synthesis and recommendations of the economic evaluation of OHS interventions at the company level conference

PROBLEM: In today's economic environment, enterprises may not be able to fund every new project aimed at promoting health and safety in the workplace. Company level economic evaluation of interventions can provide guidance in sound business decision-making. The Economic Evaluation of Occupational Health and Safety Interventions at the Company Level Meeting brought together members of the global occupational safety and health community interested in encouraging the use of economic knowledge and tools to evaluate economic gains from occupational health and safety interventions. DISCUSSION: Discussions of the six models presented explored similarities, reliability, and potential use by corporate enterprises, small and medium enterprises, developing and transitioning nations, and economic theorists. Each group provided specific projects that could be pursued to advance knowledge in the area of economic evaluation at the company level. CONCLUSION: This conference established pathway to incorporate economic evaluation of health and safety interventions or programs at the workplace.     

自动搅拌萃取-紫外分光光度法测定常州市城市饮用水水源地石油类

根据《水质石油类的测定紫外分光光度法(试行)》(HJ 970—2018)的要求,以正己烷为溶剂,采用自行设计的搅拌式液液萃取器处理样品,萃取相经硅酸镁吸附脱除极性物质后,用紫外分光光度法测定常州市城市饮用水水源地的石油类指标。结果表明:方法检出限为0.01 mg/L,线性范围为0~16.0 mg/L,相关系数为0.9998,4种不同浓度配制样品测定的相对误差为-15.0%~4.0%,相对标准偏差为2.2%~8.8%。各项技术指标均满足《HJ 970—2018》相关质量控制要求,相比手动萃取-红外分光光度法,自动搅拌萃取-紫外分光光度法能有效提高分析效率和降低职业危害。     

某铁路隧道内空气污染物分析及治理

对某铁路隧道空气污染物及其来源进行调查分析,调查结果表明,该铁路隧道内的污染物呈增加趋势,部分时间段污染物浓度超过国家标准。在分析隧道内空气污染源及产生原因的基础上,提出在隧道预留风机段内加装机械通风、优化生产流程、加强个人防护等治理建议。     

A comparative analysis of safety management and safety performance in twelve construction projects

IntroductionSafety management in construction is complicated due to the complex “nature” of the construction industry. The aim of this research was to identify safety management factors (e.g., risk management and site management), contextual factors (e.g., organisational complexity) and combinations of such factors connected to safety performance. Method: Twelve construction projects were selected to compare their safety management and safety performance. An analytical framework was developed based on previous research, regulations, and standards where each management factor was defined. We employed qualitative comparative analysis (QCA) to produce case knowledge, compare the cases, and identify connections between the factors and safety performance. The material collected and analyzed included, for example, construction planning documents, reports from OHS-inspections, safety indicators, and interviews with project leaders and OHS experts. Results and conclusions: The research showed that: (a) the average score on 12 safety management factors was higher among projects with high safety performance compared to projects with low safety performance; (b) high safety performance can be achieved with both high and low construction complexity and organizational complexity, but these factors complicate coordination of actors and operations; (c) it is possible to achieve high safety performance despite relatively poor performance on many safety management factors; (d) eight safety management factors were found to be “necessary” for high safety performance, namely roles and responsibilities, project management, OHS management and integration, safety climate, learning, site management, staff management, and operative risk management. Site management, operative risk management, and staff management were the three factors most strongly connected to safety performance. Practical implications: Construction stakeholders should understand that the ability to achieve high safety performance in construction projects is connected to key safety management factors, contextual factors, and combinations of such factors.