Toxic effects of Hydrilla verticillata exposed to toluene, ethylbenzene and xylene and safety assessment for protecting aquatic macrophytes

Little information is available about the toxicity of toluene, ethylbenzene and xylene acting on macrophytes, and their toxicity data are rarely used in regulation and criteria decisions. The results extended the knowledge on toxic effects of toluene, ethylbenzene and xylene on aquatic plants. The responses of Hydrilla verticillata to these pollutants were investigated. Chlorophyll levels, lipid peroxidation, and antioxidant enzymes (superoxide dismutase and guaiacol peroxidase) showed diverse responses at different concentrations of toluene, ethylbenzene and xylene. The linear regression analyses were performed respectively, suggesting the concentrations of toluene, ethylbenzene and xylene expected to protect aquatic macrophytes were 7.30 mg L⁻¹, 1.15 mg L⁻¹ and 2.36 mg L⁻¹, respectively. This study emphasized that aquatic plants are also sensitive to organic pollutants as fishes and zooplanktons, indicating that macrophytes could be helpful in predicting the toxicity of these pollutants and should be considered in regulation and criteria decisions for aquatic environment protection.     

容检规中非圆形缺陷可接受准则的安全裕度

文章以国内典型压力容器用材245R为例，采用GB／T19624~断裂力学评价方法对于《压力容器定期检验规程》表5、表6中的超标非圆形缺陷可接受准则的安全裕度进行评价，评价结果表明其中可接受准则的部分规定不够保守，就此作者给出相关的修改建议。     

The role of toxicology in the evaluation of new agrochemicals

Abstract

The use of agrochemicals like crop protecting agents, veterinary disinfectants, and wood preservatives may result in (un)intentional exposure of the environment, animals and man. This paper deals with current testing strategies to assess the potential health risks for humans exposed to these chemicals during production or application or via consumption of foods containing pesticide residues.

Principles and procedures for safety assessment of pesticide residues in food as developed by WHO/FAO are described. Different types of toxicity studies in mammalian test animal species are discussed and a strategy is outlined in order to characterize the toxicity profile of a compound and the relationship between applied doses and adverse effects. Safety testing of agrochemicals should be carried out in relation to its intended use, and in particular attention will be paid to toxicity testing of residues of pesticides in food. Extrapolation of results from animal studies to humans and the use of safety factors is discussed.

Besides the use of animal protocol studies for safety testing of agrochemicals, the potential use of in‐vitro models derived from organs and tissues of animals is discussed. Data on the in‐vitro metabolism of thiabendazole, aldicarb and alachlor are discussed in order to demonstrate that such data may complement or partly substitute whole animal experimentation.

Principles and procedures for safety testing of residues of agrochemicals in food as applied during the last three decades, constitute a ‘safety‐first’ approach, providing sufficient safety margins for the consumer of foods which may contain low levels of residues of agrochemicals.     

Safety testing of pesticides and methods of evaluating human exposure in the field

Abstract

The importance of field surveys to provide data on acute pesticide hazards is discussed. The types of questions which small field surveys of pesticide exposure should answer are presented. In addition to protective clothing, the value of distance, time, and personal hygiene in reducing exposure are considered. Finally, the importance of an adequate data base for the development of protocols and guidelines for public protection is discussed.     

Ecotoxicological effects assessment in the Netherlands: Recent developments

In a recently published annex to the National Environmental Policy Plan of the Netherlands (1989), attention was paid to ecotoxicological effects assessment. The proposed procedure was based on the advice of the Health Council of the Netherlands (1989) on risk assessment of toxic chemicals for ecosystems. The various extrapolation methods described by the Health Council are critically discussed in this paper. The extrapolation method of Van Straalen and Denneman (1989) is evaluated for eight chemicals and 11 aquatic species. Conclusions are drawn about the quality and quantity of the ecotoxicological data needed for aquatic effects assessment. For the soil—a compartment that is often at risk—ecotoxicological effects assessment is not possible because suitable ecotoxicological test methods still have to be developed.     

关于安全经济学的探讨

本文主要论述了如下基本概念问题: 1、安全的主要经济功能是保障社会经济的增值和有效地减少事故的经济损失。本文试图构造增值函数I(S)和损失函数L(S)来描述其功能。 2、安全经济学的基本任务是研究安全的经济效益和安全的经济利益规律,使其有效地调整和协调安全与经济的关系,指导安全经济决策。 3、本文试提出发展安全经济学应遵循的三个基本原理。 4、为综合揭示安全经济规律,本文还探讨了安全经济的功能函数F(S)、成本函数C(S)、负担函数B(S)和效益函数E(S)。 5、针对实际应用,本文还提出了一种安全投资的评价方法及其优化理论。     

试用“三论”探索我国安全生产宏观管理模式

本文试用系统论、控制论和信息论的观点探索我国安全生产宏管理模式。文中主要分析了生产安全系统的内涵;行业生产安全系统的内涵;以及生产安全系统的宏观控制的内涵。并指出了行业生产安全系统是生产安全系统的主体控制系统,劳动安全监察系统是生产安全系统的强化控制系统。     

安全科学技术也是第一生产力(第一部份)

本文提出安全科学技术也是第一生产力的观点。文中简析了科学、技术和科学技术的内涵及其相互关系;研究了科学技术与生产力的关系;阐述安全科学技术也是第一生产力:探讨了发展高科技与安全科学技术的关系;安全科学技术发展中应注意的问题。     

关于现代中国安全生产管理体系研究：管理、法规、文化

对我国安全生产管理的宏观及微观形势分析，论证了安全生产与国民经济的关系。特别指出从根本上遏制新的事故高峰，关键应强化“大安全观”的安全生产管理体系建设与实践。研究向市场经济转换过程中的中国安全减灾业的发展及管理思路，重点探索了体系化管理、安全文化及安全生产法的主题。     

风险学与安全减灾─—从参加“风险科学与管理”国际研讨会谈起

阐述建立风险学的重要性，探讨了开展安全减灾风险评价与管理的关键问题。概要介绍国内外风险水平的表征、识别方法及指标体系，并提出风险管理的基本原则。引入风险地图、危机管理、风险数学、应急与预警等现代概念及方法，基本反映了在瑞典召开的“新区开发中的风险科学与管理”国际会议的内容。