Adverse perinatal outcome in patients screen-positive for neural tube defects and fetal down syndrome

An association between various abnormal mid-trimester maternal serum analyte values and adverse perinatal outcome has been reported. From an original sample of 14 857 women, we observed five women who were ‘screen-positive’ for both neural tube defects [maternal serum alpha-fetoprotein (MSAFP) ≥2·5 multiples of the median] and Down syndrome [risk ≥1/274 using MSAFP, maternal serum unconjugated oestriol (MSuE3), maternal serum human chorionic gonadotropin (MShCG), and maternal age]. The four patients who elected to undergo amniocentesis all demonstrated both normal karyotype and normal amniotic fluid AFP levels. All five cases were associated with intrauterine growth retardation (IUGR) and abnormal pregnancy outcomes. Two cases exhibiting severe IUGR on ultrasound examination were terminated at 19·1 and 21·2 weeks, respectively; the former also exhibited fetal calcifications and positive maternal serology for toxoplasmosis. In another case, fetal demise occurred at 36 weeks' gestation in a patient who had been treated for syphilis in the second trimester. Neither infection was confirmed in fetal tissue studies. Though resulting in live births, the remaining two cases required operative deliveries; emergency Caesarean sections for fetal distress were performed at 38 and 32 weeks, respectively, the latter case being associated with severe pre-eclampsia. We conclude that elevated mid-trimester MSAFP levels concurrent with maternal serum analyte values associated with increased risk for fetal Down syndrome may presage a poor perinatal outcome, particularly IUGR and possibly congenital infection.     

Glial fibrillary acidic protein in amniotic fluids from pregnancies with fetal neural tube defects

The glial fibrillary acidic protein (GFAP) is the subunit protein of intermediate filaments in astrocytes and closely related cell types. By means of an enzyme immunoassay we have determined the concentration of GFAP in amniotic fluids from normal pregnancies and from pregnancies complicated by various fetal malformations. The group of 20 cases of fetal anencephaly had a significantly higher mean amniotic fluid GFAP concentration (115 μg/1±133.6 (S.D.), range 6–378 μg/1) than the control group of 117 normal pregnancies (13 μg/1k±5.5 (S.D.), range 0–31 μg/1), (P<0.001). Two cases of fetal encephalocele likewise had very high amniotic fluid GFAP concentrations. None of the other cases of fetal malformations investigated, including 12 cases of spina bifida, had increased amniotic fluid GFAP concentrations. We conclude that determination of the amniotic fluid GFAP concentration may give additional information in the prenatal diagnosis of fetal nervous system malformations.     

螺旋状中空纤维膜吸收器脱硫性能的研究

用自组装的膜吸收器试验研究了不同操作条件下的烟气脱硫特性。实验结果表明，脱硫过程传质阻力主要集中在气相和膜上，利用螺旋管技术可以强化气相的传质。     

天然气引射调峰系统的噪声形成及其治理研究

采用天然气引射调峰技术，能使上海某储配站10台天然气高压球罐的储气调峰能率提高68％，大大有助于解决天然气用气高峰时的供需平衡问题，并能节约初投资人民币1亿元。但使用超音速引射器后，当球罐压力下降到某一值时会产生高频噪声，影响管束区操作环境。本文分析了噪声产生的原因．提出了合理的噪声治理方案，并进行了方案的实施。实践证明：噪声治理效果良好，降低了管束区噪声污染，达到了国家“工业企业噪声卫生标准”。     

GC/MS测定环境空气中的糠醛

本文采用活性炭管对糠醛厂厂界空气中糠醛进行吸附,选用适当的有机溶剂进行解吸,运用气相色谱-质谱(GC/MS)方法对空气中糠醛进行定性、定量分析。此方法适用于环境空气中糠醛的测定。     

非均匀火灾作用下方形钢管混凝土短柱剩余承载力研究

为研究非均匀火灾作用下方形钢管混凝土短柱剩余承载力,在合理采用钢材和混凝土本构关系的前提下,基于ABAQUS建立了火灾后钢管混凝土柱相继热力耦合分析模型,并依据试验数据验证模型有效性。在此基础上进行了单面、相对两面受火状态下方形钢管混凝土短柱的轴压工作机理分析和参数分析,结果表明:受火方式对构件温度场及受力机理影响较大;受火时间、截面边长、防火保护层厚度是构件非均匀受火后剩余承载力的主要影响参数。在工程常用范围内,回归了两种受火方式下方钢管轴压短柱剩余承载力影响系数计算公式,可为该类构件在火灾后的修复提供参考。     

单面受火的方中空夹层钢管混凝土短柱耐火极限

为研究单面受火的方中空夹层钢管混凝土短柱耐火极限,在合理选择材料本构关系和边界条件的基础上,利用ABAQUS软件建立了高温下方中空夹层钢管混凝土短柱温度场和力学场分析模型,通过与试验数据对比验证,结果吻合良好。基于此模型,对不同的混凝土强度、钢管强度、内钢管厚度、空心率、荷载比进行耐火极限参数分析,并定量给出计算此类构件耐火极限的简化公式。研究结果表明:荷载比是构件耐火极限的主要影响参数。荷载比越大,构件的耐火极限越小。     

新型甲醛被动式检气管的研制

新研制的甲醛被动式检气管是建立在气体分子扩散和化学吸收原理基础上的，检气管内的惰性担体上浸渍了对甲醛特效的希夫试剂。当管内进入甲醛气体时，即发生显色反应，检气管的显色长度的平方与甲醛浓度及采样时间的乘积成线性关系。检出下限为０．０１５ｍｇ＃Ｌ（采样５ｈ），它集采样与分析为一体，结构简单，不需动力，便于携带和操作方便，应用于检测某厂刨花板车间和制胶车间的甲醛气体，与传统的注射器采样比色分析法对比，结     

管材弯曲工艺研究新进展

管材成形由于容易满足塑性成形产品轻量化、强韧化和低耗高效、精确制造等方面的要求 ,在航空航天、汽车工业等许多行业中得到广泛的应用。管材弯曲成形工艺的研究是其中备受关注并得到迅速发展的重要领域之一。介绍了几种新的弯管工艺 ,阐述了国内外弯管工艺的最新研究进展和发展趋势。     

分流焊合模成形管材过程的数值模拟研究

采用FEM方法对分流焊合模成形管材的挤压变形过程进行了三维模拟,给出了管材挤压过程中铝合金的应力、应变及流动速度等的分布和变化。