武钢一炼钢厂平炉跨间7.15m平台钢梁加固

简述了针对平台粱变形进行加固改造,以提高其使用寿命的方法.     

Prenatal diagnosis of a de novo supernumerary marker derived from chromosome 16

Marker chromosomes are supernumerary chromosomes of unknown origin and are seldom found in prenatal diagnosis. Application of fluorescent in situ hybridization (FISH) allows the identification of the chromosomal origin of markers. Estimation of the risk of an abnormal phenotype outcome can be enabled by collecting data on phenotypes associated with markers of the same chromosomal origin. So far only very few cases of prenatal diagnosis of de novo supernumerary markers derived from chromosome 16 have been reported. Here the prenatal diagnosis of a de novo supernumerary marker chromosome 16 is described and the relevant literature discussed. Copyright © 2001 John Wiley & Sons, Ltd.     

Identification of a small supernumerary marker chromosome,r(2)(p10q11.2), and the problem of determining prognosis

The identification of small supernumerary marker chromosomes (SMCs) and the elucidation of their clinical significance remain two of the problems in classical human cytogenetics. We observed a small supernumerary ring in amniotic fluid cell cultures and identified its origin as r(2)(p10q11.2) and its extent by means of fluorescent in situ hybridisation (FISH). Uniparental disomy (UPD) was excluded by microsatellite analysis using polymorphic markers localised in the same region. On the basis of normal ultrasonographic checks, the patient decided to continue the pregnancy. A normal female was delivered at term and subsequent neonatal follow-ups confirmed the normal phenotype and development. In the present case, genetic counselling was not helpful because of the absence of reference cases. Detailed characterisation made it possible to correlate the normal baby phenotype with the trisomic 2p10-2q11.2 genomic region. Further molecular cytogenetic investigations of SMCs classified by DNA content and pregnancy outcome data should improve genetic counselling and risk evaluation. Copyright © 2001 John Wiley & Sons, Ltd.     

基于双向算法的湖库允许纳污负荷量计算及案例

为了加强湖库流域水环境保护与污染负荷排放管理,支持湖库控制单元允许纳污负荷量的计算和污染负荷分配决策的制定,在总结国内外环境容量相关研究的基础上,针对现状水环境总量控制技术中允许纳污负荷计算与分配环节存在的问题,提出基于双向算法的湖库允许纳污负荷量计算方法.并以EFDC(environmental fluid dynamic code)水环境模型为核心,通过模型概化、参数率定等建模技术与方法的研究,利用估算与精算相结合的方法制定排污情景,并应用模型完成情景分析.应用多次情景试算、分析的方法,制定优化的排污情景,从而计算出湖库允许纳污负荷量.最后以辽宁省柴河水库为实证区进行方法的应用,证明了方法具备科学性与计算精度.     

引信电磁感应装定校验纠错码研究

对在引信电磁感应装定中可采用的不同检验纠错码方式进行了理论分析,最终选取循环码并采用循环冗余校验法进行校验纠错。将11位信息码元进行分组,选取其中一组（110）这3个信息码元作为研究对象,求出其生成矩阵与校验矩阵,得到加入校验码后的码元组成（1100101）,根据其矩阵设计出编码与解码的电路图。为了验证加入校验码后的校验效果,用MATLAB软件对（7,3）循环码在噪声情况下的传输误码率进行了仿真验证,得到的结果与理论分析结果一致。     

大气颗粒物的源成分谱研究现状综述

调研国内外大气颗粒物排放源成分谱研究情况,对排放源的分类、颗粒物的化学组分和测定、各类排放源的成分谱组成、研究情况以及排放源的标识元素情况进行了综述.     

A further case with a small supernumerary marker chromosome (sSMC) derived from chromosome 1—evidence for high variability in mosaicism in different tissues of sSMC carriers

A prenatally ascertained case with a de novo small supernumerary marker chromosome (sSMC) derived from chromosome 1 is reported. Due to a fetal heart defect the parents decided in favour of an induced abortion. Postmortem, a molecular cytogenetic study on eleven formalin fixed, paraffin-embedded tissues of the fetus was performed, to further characterize the levels of mosaicism of the sSMC(1). sSMC presence varied between 13 and 62% within different tissues of sSMC carriers. This finding is something common in sSMC carriers and could explain why up to the present no clinical correlations for sSMC mosaicism and clinical outcome in the corresponding carriers could be established. Copyright © 2007 John Wiley & Sons, Ltd.     

5个中国人群Y染色体上17个双等位基因位点的多态性分析

选取Y染色体非重组区上17个双等位基因位点,利用ASPCR和PCR的方法对云南的怒族、傈僳族、纳西族、青海的撒拉族和福建的畲族进行了检测分型,确定了每一个体由这17个位点所构成的单倍型,并与国内其它20个民族群体的结果一起进行了主成分分析.结果显示,YAP、M15、M89、M9、M119、M95、M88、M45、M122、M134、M17、M120等12个位点在5个民族群体中均有不同的频率分布,其余5个位点没有发现多态变异,其中M122(C)在怒族、傈僳族、纳西族、撒拉族和畲族中的频率分别是82.1%、31.6%、5.9%、20%、69.3%;YAP 只在撒拉族中有2.2%的频率;傈僳族的M95(T)的频率最高,达68.4%.5个群体中共发现了12种单倍型,单倍型频率主要集中分布在H5、H6、H8、H11和H12,各民族群体的单倍型有各自的分布特点.主成分分析的结果显示:傈僳族则与苗瑶、侗壮语族的民族群体聚到了A簇;畲族、怒族与汉族群体紧密,聚到了B簇;而撒拉族、纳西族则与藏缅语族和阿尔泰语系的民族群体聚为C簇.图1表2参20     

高校实验室风险信息分类及采集传输系统研究*

高校实验室突发事故发生后,为准确获取灾情信息,实现快速响应和紧急救援,研究救援现场风险信息快速采集技术,按固有信息和动态信息对风险信息进行分类和编码,建立实验室风险信息采集传输系统,以某高校实验室着火事件为例,模拟应急响应全过程。结果表明:风险信息采集传输系统实现了信息的实时采集与上报以及救援资源的合理分配与管理,研究结果可促进高校实验室应急服务领域的技术进步和创新。