Short communication the natural history of fetal cytomegalovirus infection as assessed by serial ultrasound and fetal blood sampling: A case report

A patient in whom intrauterine fetal cytomegalovirus (CMV) infection was diagnosed at approximately 25 weeks' gestation is presented. The fetus was evaluated by serial fetal blood samplings and ultrasound examinations. The fetus manifested evidence of severe thrombocytopenia and hepatic inflammation, with recovery over a period of approximately 8 weeks. The initial sonographic findings of marked fetal ascites and cardiomegaly gradually resolved; ventriculomegaly developed during the third trimester. At delivery, the baby was morphologically normal with the exception of mild ventriculomegaly. Cord blood was negative for CMV IgM but urine was culture-positive for CMV. At age 3, the child has a severe but stable unilateral hearing deficit and is otherwise developmentally normal. This case demonstrates the utility of serial ultrasound and fetal blood sampling in the prenatal diagnosis and management of fetal CMV infection.     

黄骅坳陷孔古4井原油的成因探讨

通过对黄骅孔古4井上古生界原油的地球化学特征及其与石炭系煤系烃源岩的亲缘关系研究,特别是与奥陶系原油、灰岩、下第三系原油饱和烃的甾、萜烷精细“指纹”对比研究后,我们认为孔古4井原油应属于上古生界煤系地层自生自储的原生油气藏,而并非下第三系抑或下古生界碳酸盐岩所生。孔古4井上古生界原生油气藏的发现对于华北地区特别是华北北部黄骅坳陷上古生界煤系地层的油气勘探具有重要意义。     

韶石山- -丹霞地貌丹霞山的姐妹山

广东北部丹霞盆地是中、新生代内陆山间盆地，由早第三纪红色岩层构成的丹霞山和韶石山，是丹霞地貌命名标准地区的姐妹山。韶石山因舜帝南巡奏韶乐而得名，后为韶关市命名的主山。自古以三十六奇石著称于世。近年已逐步开发和开展旅游活动。     

冷水箐铜镍硫化物矿床的铂族元素地球化学特征

采用镍锍试金预处理中子活化分析方法，测定了冷水箐铜镍硫化物矿床的矿石和含矿围岩的铂族元素含量，探讨了岩浆演化和熔离作用过程中铂族元素的地球化学行为和贵金属配分型式。结果表明，冷水箐矿床的铂族元素配分型式与玄武岩浆有关的铜镍硫化物矿床相似，而明显不同于与科马提岩浆有关的铜镍硫化物矿床。认为冷水箐岩体镁铁－超镁铁岩的原始岩浆为玄武岩浆。     

东大湖养鱼场水质遗传毒理的检测研究

本文报道了利用蚕豆根尖微核技术和鱼周血有核红细胞微核技术检测东大潮5个渔场的水质污染情况。结果为：各渔场蚕豆根尖MCN‰与对照（自来水）存在显著差异（F＞F(0．01)，P＜0．01），根据污染指数划分：A、B两渔场为重污染，C、D为中度污染，E为轻污染。各渔场鱼周血有核红细胞MCN‰与无明显污染源水体（柏录）存在着显著性差异（F＞F(0．01)，P＜0．01）。两种方法检测结果呈一致性，污染程度为A≈B＞C≈D＞E。微核率变化主要受污染源性质及位置的影响。将两种遗传毒性检测方法与化学方法检测相配合．能全面、准确、快速地监测水体污染状况，具有广泛的应用前景。     

Prenatal diagnosis of X-linked mental retardation with fragile (X) using fetoscopy and fetal blood sampling

Pure fetal blood, (uncontaminated with maternal blood), was obtained from two male fetuses at risk for X-linked mental retardation with fragile(X) at Xq27–28 by direct vision fetoscopy and fetal blood sampling. Both were shown to have this fragile site on the X chromosome while nine other fetal blood samples from pregnancies at risk for other X-linked diseases, or haemoglobinopathies did not show fragile sites at Xq27–28, and a blood sample from an abortus showed only 1 fragile site in 95 mitoses. Both pregnancies were terminated, cultures established from fetal tissues, and the diagnosis confirmed in each case. The problems of demonstrating the fragile site in tissues other than fetal blood in these pregnancies (such as amniotic fluid cells or fibroblasts from fetal tissues) are discussed.     

废旧干电池对泥鳅的致毒作用

以抗污染能力强的泥鳅(Misgurnus anguillicadatus)为实验材料,研究了废旧干电池污染的水源对水生生物的毒害作用。结果表明,泥鳅受毒害程度与水体中废旧干电池的数量和暴露时间成正相关关系;对受毒害但未死亡的个体断尾取血,显微镜下观察血红细胞的形态、结构,发现在废旧干电池污染的水体中残存的个体,其血红细胞的变异率远远超过生活在正常水体中的个体。     

试论环境集团诉讼制度

论述了建立环境集团诉讼制度的必要性、基本慨念、特征和诉讼程序中的几个问题,并对我国建立该项制度提出了一些探讨性建议。     

液相色谱法测定血中巴比妥类药物

本文建立了血样中巴比妥类药物的液相色谱定性定量分析方法，该法采用Ｃ１８反相色谱柱分离，二极管矩检测器检测，能一次性将４种药物分析和鉴定，通过色谱峰的保留时间和紫外吸收光谱定性，以色谱的峰面积定量，标准曲线的直线范围在０－１０μｇ．ｍ１＾－１，相关系数在０．９９以上。血中药物经溶浏萃取，回收率在９５％以上，血中的杂质不影响药物检测。方法的最小检出浓度为１０ｎｇ．ｍ１＾－１，本法可用于临床中毒样品的分