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151.
Ohmichi K Komiyama M Matsuno Y Takanashi Y Miyamoto H Kadota T Maekawa M Toyama Y Tatsugi Y Kohno T Ohmichi M Mori C 《Environmental science and pollution research international》2006,13(2):120-124
Goal, Scope and Background Cadavers for gross anatomy laboratories are usually prepared by using embalming fluid which contains formaldehyde (FA) as
a principal component. During the process of dissection, FA vapors are emitted from the cadavers, resulting in the exposure
of medical students and their instructors to elevated levels of FA in the laboratory. The American Conference of Governmental
Industrial Hygienists (ACGIH) has set a ceiling limit for FA at 0.3 ppm. In Japan, the Ministry of Health, Labour and Welfare
has set an air quality guideline defining two limit values for environmental exposure to FA: 0.08 ppm as an average for general
workplaces and 0.25 ppm for specific workplaces such as an FA factory. Although there are many reports on indoor FA concentrations
in gross anatomy laboratories, only a few reports have described personal FA exposure levels. The purpose of the present study
was to clarify personal exposure levels as well as indoor FA concentrations in our laboratory in order to investigate the
relationship between them.
Methods The gross anatomy laboratory was evaluated in the 4th, 10th and 18th sessions of 20 laboratory sessions in total over a period
of 10 weeks. Air samples were collected using a diffusive sampling device for organic carbonyl compounds. Area samples were
taken in the center and four corners of the laboratory during the entire time of each session (4-6 hours). Personal samples
were collected from instructors and students using a sampling device pinned on each person's lapel, and they were 1.1 to 6
hours in duration. Analysis was carried out using high performance liquid chromatography.
Results and Discussion Room averages of FA concentrations were 0.45, 0.38 and 0.68 ppm for the 4th, 10th and 18th sessions, respectively, ranging
from 0.23 to 1.03 ppm. These levels were comparable to or relatively lower than the levels reported previously, but were still
higher than the guideline limit for specific workplaces in Japan and the ACGIH ceiling limit. The indoor FA concentrations
varied depending on the contents of laboratory sessions and seemed to increase when body cavity or deep structures were being
dissected. In all sessions but the 4th, FA levels at the center of the room were higher than those in the corners. This might
be related to the arrangement of air supply diffusers and return grills. However, it cannot be ruled out that FA levels in
the corners were lowered by leakage of FA through the doors and windows. Average personal exposure levels were 0.80, 0.45
and 0.51 ppm for instructors and 1.02, 1.08 and 0.89 ppm for students for the 4th, 10th and 18th session, respectively. The
exposure levels of students were significantly higher than the mean indoor FA concentrations in the 4th and 10th sessions,
and the same tendency was also observed in the 18th session. The personal exposure level of instructors was also significantly
higher than the indoor FA level in the 4th session, while they were almost the same in the 10th and 18th sessions. Differences
in behavior during the sessions might reflect the differential personal exposure levels between students and instructors.
Conclusion The present study revealed that, if a person is close to the cadavers during the gross anatomy laboratory, his/her personal
exposure level is possibly 2 to 3-fold higher than the mean indoor FA concentration. This should be considered in the risk
assessment of FA in gross anatomy laboratories.
Recommendation and Outlook If the risk of FA in gross anatomy laboratories is assessed based on the indoor FA levels, the possibility that personal
exposure levels are 2 to 3-fold higher than the mean indoor FA level should be taken into account. Otherwise, the risk should
be assessed based on the personal exposure levels. However, it is hard to measure everyone's exposure level. Therefore, further
studies are necessary to develop a method of personal exposure assessment from the indoor FA concentration. 相似文献
152.
153.
新时期高校实验室安全管理的分析与思考 总被引:25,自引:2,他引:25
高校实验室是进行实验教学和开展科学研究的重要基地,是理论联系实际,人才培养和科技创新的必备场所。实验室的安全对高校乃至全社会的安全和稳定都至关重要。笔者分析了新时期高校实验室安全管理的现状、特点以及存在的问题;对高校实验室的安全、环保管理发表了自己的见解,提出了“以人为本”、“安全第一,预防为主”,“依法整治”的观点,它是建设和管理高校实验室的基本思路,也是实现高校实验室安全的基本原则;同时调强了保护教师和学生的实验室安全与健康,不仅仅是实验室的安全问题,也是校园安全管理工作的重要组成部分。 相似文献
154.
155.
基于驾驶员在行驶过程中的注意力大部分集中在车辆的正前方,忽略了道路两侧的情况的视觉特性,更容易引发交通事故的问题。环境比为评价路边物体可视度的指标,为了保证评价的准确性,尤其是保障夜间行驶的良好视觉环境,可以根据路灯设置的基本原则及照明强度与可见度的关联特性,使用MATLAB(矩阵实验室)对环境比进行模拟分析,从理论的角度研究其相关的影响因素,提出了采取减小灯具倾斜角、缩短灯具悬臂悬挑长度以及增加路灯灯杆安装位置与路缘石的距离等措施可以提高道路照明环境比的观点,可以作为路灯改造工程、路灯灯具外形的设计以及夜间行驶事故分析的理论基础。 相似文献
156.
Donald S. Cherry Robert C. Hoehn Samuel S. Waldo Durwood H. Willis John Cairns Kenneth L. Dickson 《Journal of the American Water Resources Association》1977,13(5):1047-1056
ABSTRACT: The responses of the spotfin shiner (Notropis spilopterus) and bluntnose minnow (Pimephales notatus) to intermittent chlorine discharges from a fossil fuel power plant in the New River were investigated by seine collections in the chlorinated discharge channel, and chlorine avoidances were obtained in a field laboratory at the power plant in Glen Lyn, Virginia. No fish were captured by seine during chlorination periods when the total chlorine (TCR) and free chlorine (FCR) residuals were, respectively, 0.46 and 0.27 mg/1 or higher at river water temperatures of 12 C or less. For collections made between eight-hour chlorination periods, the number of fish was reduced by approximately 50% at 0.20 and 0.06 mg/1 TCR and FCR, respectively. Significant (0.05 level) laboratory avoidances occurred at 0.10 to 0.20 mg/1 TCR (0.03 to 0.14 mg/1 FCR) for both species when exposed to increasing TCR concentrations of 0.10, 0.20, 0.30 and 0.40 mg/1. Responses varied with acclimation temperature (6, 12, 18 and 24 C) with no consisteent trends between species. When exposed to a constant TCR concentration during any one test (0.14, 0.18 and 0.26 mg/1 for the spotfin shiner, and 0.11 and 0.17 mg/1 for the bluntnose minnow), significant avoidances were observed at 0.26 and 0.17 mg/1 for each species, respectively. In all laboratory trials, occurrence or residence times decreased with increasing chlorine concentration, with residence times as high as 64.7% at 0.10 mg/1 TCR and as low as 8.3% at 0.40 mg/1 being observed. 相似文献
157.
目的建立可用于大型气候环境实验室初期设计热负荷计算的方法和模型,对实验室的热负荷进行计算,为制冷系统选型提供依据。方法通过分析实验室的组成结构和热负荷来源,基于状态空间法建立各部分的热负荷计算方法,在Simulink中搭建以制冷量为输入参数的实验室热负荷计算仿真模型,对实验室空载降温过程进行仿真。结果该仿真模型可以快速对实验室热负荷进行计算,并且可以方便地增减热负荷模块,实验室在降温过程中热负荷达3500 k W以上,地板结构的热负荷占到了总热负荷50%以上。结论热负荷计算结果可应用于空调系统和制冷系统的设计和选型,以及控制策略的优化。 相似文献
158.
目的研究不同试验方式下聚碳酸酯的光老化行为。方法对比聚碳酸酯在自然暴露试验、自然加速光老化试验及实验室光源暴露试验中的缺口冲击强度变化,分析各种加速试验方式对自然暴露试验的模拟性。结果聚碳酸酯在拉萨户外自然暴露中,其缺口冲击强度随试验时间的延长而降低。单轴跟踪暴露和跟踪太阳反射聚能暴露这两种自然加速光老化试验方式对户外自然暴露的模拟性均较好,加速倍率分别约为1.5,6。氙弧灯下的暴露试验对自然暴露试验的模拟性比紫外冷荧灯、金属卤素灯高。结论跟踪太阳反射聚能暴露、氙弧灯下暴露可推荐为评价聚碳酸酯光老化行为的加速试验方式。 相似文献
159.
160.
便携式分析仪在环境突发性事件能进行快速现场分析,为应急处理及时提供了依据,但在定量上存在一定误差。本文探讨了4160-2型便携式甲醛现场分析仪的监测结果与传统实验室分析结果的可比性,从而保证为应急处理中能准确引用该仪器的监测数据。 相似文献