三丁基锡对正常人胚胎羊膜细胞凋亡相关蛋白表达的影响

首次采用蛋白质印迹法研究三丁基锡(tributyltin,TBT)对正常人胚胎羊膜细胞FL(human amniotic cells)的Bcl-2、Bax和p53表达的影响.结果显示,在0、1、2、3、4μmol·L-1三丁基锡下作用2 h后,FL细胞的Bax蛋白表达量随浓度增加逐渐升高,Bcl-2蛋白表达量仅在3、4μmol·L-1浓度组相比于对照组明显下降.作为凋亡是否发生的决定因素,Bax/Bcl-2比值在三丁基锡高浓度组(3、4μmol·L-1)相比于对照有显著升高;而p53蛋白表达量没有明显变化.研究表明,Bcl-2和Bax参与了TBT诱导的细胞凋亡.     

A rare non-heterochromatic 9p+ variant in two amniotic fluid cell cultures

Two cases of amniotic fluid cell cultures are reported, where a familial, non-heterochromatic 9p+ variant has been found.     

PRENATAL DIAGNOSIS OF CYSTIC HYGROMA AND CHORIOANGIOMA IN THE WOLF-HIRSCHHORN SYNDROME

We report the prenatal diagnosis of Wolf-Hirschhorn syndrome (4p –) in a 24-week-old fetus. Echographic features included cystic hygroma, a complex heart defect with right ventricular hypoplasia, and a large placental chorioangioma. We suggest that chorioangioma may be associated with chromosomal imbalance and that systematic careful morphologic examination of the fetus and karyotyping of any pregnancy in which large chorioangioma is detected is advisable. Jugular lymphatic obstruction sequence has not been reported so far in association with 4p– syndrome.     

Synthesis and environmental degradation of polyesters based on poly (ε-caprolactone)

Poly (p616k5m33496xt77/xxlarge949.gif" alt="epsi" align="BASELINE" BORDER="0">-caprolactone) (PCL), poly (p616k5m33496xt77/xxlarge948.gif" alt="delta" align="BASELINE" BORDER="0">-valerolactone) (PVL), poly (p616k5m33496xt77/xxlarge949.gif" alt="epsi" align="BASELINE" BORDER="0">-caprolactone-co-p616k5m33496xt77/xxlarge948.gif" alt="delta" align="BASELINE" BORDER="0">-valerolactone) [P(CL-co-VL)], and poly (p616k5m33496xt77/xxlarge949.gif" alt="epsi" align="BASELINE" BORDER="0">-caprolactone-co-ethylene oxide-co-p616k5m33496xt77/xxlarge949.gif" alt="epsi" align="BASELINE" BORDER="0">-caprolactone) (PCL-PEO-PCL) were synthesized by ring-opening and diol-initiated polymerization of p616k5m33496xt77/xxlarge949.gif" alt="epsi" align="BASELINE" BORDER="0">-caprolactone and p616k5m33496xt77/xxlarge948.gif" alt="delta" align="BASELINE" BORDER="0">-valerolactone. The degradation of the samples by chemical hydrolysis and in a soil burial test was evaluated. It was found that PCL, PVL, and P(CL-co-VL) degrade mainly enzymatically. The rate of degradation depends on their molecular weight, chemical structure, composition, and morphology. PCL-PEO-PCL block copolymers exhibit a repelling effect to the microorganisms in the soil, which depends on the molecular weight and relative amount of PEO block in the copolymer.     

MHC, health, color, and reproductive success in sand lizards

p22312jg76168426/xxlarge8220.gif" alt="ldquo" align="MIDDLE" BORDER="0">Good genesp22312jg76168426/xxlarge8221.gif" alt="rdquo" align="MIDDLE" BORDER="0"> are genetic elements that contribute to lifetime reproductive success, regardless of an individualp22312jg76168426/xxlarge8217.gif" alt="rsquo" align="BASELINE" BORDER="0">s additional genotype. Their existence is debated, and most work has targeted their viability benefits to the offspring of choosy females. In the present study, we analyze a case of potential good genes effects in adult male sand lizards (Lacerta agilis). We show that males with a particular RFLP (Restriction Fragment Length Polymorphism) MHC genotype (O-males), as opposed to those that lack this genetic element (NO-males), have less ectoparasites under increasing physiological stress (indexed by baseline corticosterone level), and are not constrained by parasites at production of status coloration. Furthermore, O-males are more successful at mate acquisition and guard their partners longer. Ultimately, they have a higher genetic reproductive success as assigned by microsatellites.Communicated by W. Cooper     

Degradation of the herbicide imazapyr by Fenton reactions

The degradation of the herbicide imazapyr has been carried out by three advanced oxidation processes involving iron ions as catalysts: Fentonp11821rx1/xxlarge8217.gif" alt="rsquo" align="BASELINE" BORDER="0">s reagent, photo-Fenton and electro-Fenton. We show that all processes are rapid and efficient. The kinetic rate constant was found to be k=5.4×10p>9p> Mp>–1p> sp>–1p>. The mineralization of imazapyr is almost complete using the photo-Fenton and electro-Fenton processes.     

废聚苯乙烯硝化氧化制对硝基苯甲酸

研究了用聚苯乙烯废料为原料,经过硝化氧化制造具有高附加值的精细化工产品－对硝基苯甲酸。探讨了影响对硝基苯甲酸产率的因素,如硝酸的浓度和用量,压力,反应时间及催化剂用量等。结果表明,在优化条件下对硝基苯甲酸产率达５２％,产品纯度为９９％。     

有机膨润土对对硝基苯酚吸附性能的研究

以溴化十六烷基三甲铵(CTMAB)和溴化十六烷基吡啶(CPB)两种表面活性剂对钠基膨润土进行有机改性,研究了改性后的有机膨润土的用量、介质pH值、作用时间、溶液中对硝基苯酚的浓度等因素对膨润土去除对硝基苯酚的影响.结果表明:同一浓度条件下,CTMAB-有机膨润土对对硝基苯酚的去除率和吸附量均比CPB-有机膨润土高;当对硝基苯酚溶液pH在2-10范围内,2种有机膨润土对对硝基苯酚的吸附性能变化不大,但当pH上升到12时,2种有机膨润土对对硝基苯酚去除率分别下降20.5%和36.2%.2种有机膨润土对对硝基苯酚的吸附可用Freundlich方程加以描述.