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Fetal urinary insulin-like growth factor I and binding protein 3 in bilateral obstructive uropathies
L. Bussieres K. Laborde J. C. Souberbielle F. Muller M. Dommergues C. Sachs 《黑龙江环境通报》1995,15(11):1047-1055
Fetal urinary concentrations of insulin-like growth factor I (UIGF-I) and binding protein 3 (UIGFBP-3) were determined in patients with prenatal diagnosis of bilateral obstructive uropathy. Patients were retrospectively assigned to three groups, on the basis of outcome: group 1, termination of pregnancies (n = 11) with sonographic evidence of severe oligohydramnios or renal dysplasia, confirmed at histological examination; group 2, patients (n = 10) with postnatal plasma creatinine > 50 μmol/1 at the age of 1 year (1 yr-pCreat); and group 3, patients (n = 16) with 1 yr-pCreat ≤ μmol/1. The results show a significant increase in UIGF-I and UIGFBP-3 in groups 1 (18 159 ± 9083 pg/ml; 2657 ± 669 ng/ml) and 2 (1574 ± 847 pg/ml; 176 ± 50 ng/ml) in comparison with group 3 (35 ± 6 pg/ml; 21 ± 2 ng/ml). UIGF-I and UIGFBP-3 were significantly correlated with postnatal plasma creatinine, and were both sensitive (90 per cent; 80 per cent) and specific (88 per cent; 88 per cent) for prediction of elevated 1 yr-pCreat (>50 μmol/1). Fetal urinary IGF-I and IGFBP-3 are increased in severe fetal bilateral obstructive uropathy, possibly reflecting tubular dysfunction or/and increased synthesis consequent upon fetal kidney injury. Their predictive value for postnatal renal function needs further assessment. 相似文献
53.
Pollution by various heavy metals as environmental stress factors might affect bacteria. It was established that iron (Fe(III)), manganese (Mn(II)) and copper (Cu(II)) ion combinations caused effects on Enterococcus hirae that differed from the sum of the effects when the metals were added separately. It was shown that the Cu2+-Fe3+ combination decreased the growth and ATPase activity of membrane vesicles of wild-type E. hirae ATCC9790 and atpD mutant (with defective FoF1-ATPase) MS116. Addition of Mn2+-Fe3+ combinations within the same concentration range had no effects on growth compared to control (without heavy metals). ATPase activity was increased in the presence of Mn2+-Fe3+, while together with 0.2 mmol/L N,N'-dicyclohexylcarbodiimide (DCCD), ATPase activity was decreased compared to control (when only 0.2 mmol/L DCCD was present). These results indicate that heavy metals ion combinations probably affect the FOF1-ATPase, leading to conformational changes. Moreover the action may be direct or be mediated by environment redox potential. The effects observed when Fe3+ was added separately disappeared in both cases, which might be a result of competing processes between Fe3+ and other heavy metals. These findings are novel and improve the understanding of heavy metals ions effects on bacteria, and could be applied for regulation of stress response patterns in the environment. 相似文献
54.
环境污染对环境产生的负价值与环境保护对环境产生的正价值相互作用、相互抵消的运动过程,体现了环境整体价值在人类经济社会活动影响下的具体演化模式。文章探讨了环境价值的循环途径、环境资源价值的模型,并对模型进行了具体分析,以期帮助人们提高对环境价值的认识。 相似文献
55.
镉处理对大豆幼苗生长及激素含量的影响 总被引:14,自引:1,他引:14
采用室内培养试验,通过测定植株生理生化指标,研究了不同浓度Cd2+处理对大豆幼苗生长及激素含量的影响.结果表明:①不同浓度Cd2+处理对大豆幼苗地下部生长素(IAA)和赤霉素(GA3)的合成有抑制效应,对地上部生长素(IAA)和赤霉素(GA3)的合成具有低浓度下的刺激效应和高浓度下的抑制效应;对地下部、地上部玉米素(Z)和脱落酸(ABA)的合成均有刺激效应.②Cd2+处理84h对大豆幼苗根系活力、叶绿素a和叶绿素b的合成有刺激效应,对类胡萝卜素的合成无影响.③Cd2+处理对过氧化物酶(POD)活性和丙二醛(MDA)含量具有低浓度下的抑制效应和高浓度下的激活效应,且随着Cd2+浓度的增加激活效应逐渐加强.④短时间、低浓度Cd2+胁迫可刺激大豆幼苗的生理活性,以Cd2+处理浓度为0.50 mg/L时,大豆幼苗根系活力最大,IAA和GA3含量最高,POD活性最低,植物生理活性最强. 相似文献
56.
利用城市污泥堆肥及建筑弃土种植麦冬研究 总被引:1,自引:3,他引:1
将污泥堆肥产品分别与建筑弃土按0%、10%、20%、30%、40%和50%(湿重)的比例配制营养土,以麦冬为例进行180 d的栽培实验,分析了营养土对麦冬生长特性、植物体内及栽培土壤中营养学指标和重金属含量的变化规律,并通过模糊综合评价方法选择营养土较佳配制方案。实验结果表明:堆肥比例在50%时麦冬生物量增加率、新生芽数及地表部分比重为最大值,在30%时纺锤体肉质数减少率为最大值;随着营养土中堆肥比例增加,麦冬体内养分含量、重金属积累量随之增加,均在50%时达到最大值;栽培土壤养分越多损失量越多,各指残留率越低,同时全磷、全氮及K含量降低率较有效磷、碱解氮小得多,Cr降低率在5.20%~8.34%之间,Zn降低率在3.27%~17.35%之间;堆肥比例在40%以上的营养土对麦冬生长效果好,但较佳配制方案为堆肥产品占20%。 相似文献
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58.
Paoletti E Contran N Manning WJ Castagna A Ranieri A Tagliaferro F 《Environmental pollution (Barking, Essex : 1987)》2008,155(3):464-472
Treatments with ethylenediurea (EDU) protect plants from ozone foliar injury, but the processes underlying this protection are poorly understood. Adult ash trees (Fraxinus excelsior), with or without foliar ozone symptoms in previous years, were treated with EDU at 450ppm by gravitational trunk infusion in May-September 2005 (32.5ppmh AOT40). At 30-day intervals, shoot growth, gas exchange, chlorophyll a fluorescence, and water potential were determined. In September, several biochemical parameters were measured. The protective influence of EDU was supported by enhancement in the number of leaflets. EDU did not contribute its nitrogen to leaf tissue as a fertiliser, as determined from lack of difference in foliar N between treatments. Both biochemical (increase in ascorbate-peroxidase and ascorbic acid, and decrease in apoplastic hydrogen peroxide) and biophysical (decrease in stomatal conductance) processes regulated EDU action. As total ascorbic acid increased only in the asymptomatic trees, its role in alleviating O(3) effects on leaf growth and visible injury is controversial. 相似文献
59.
Rita Castro Sofia Pereira Ana Lima Sofia Corticeiro Mnica Vlega Eduarda Pereira Armando Duarte Etelvina Figueira 《Chemosphere》2009,76(10):1348-1355
This work evaluates the role of a plant community in mercury (Hg) stabilization and mobility in a contaminated Portuguese salt marsh. With this aim, the distribution of Hg in below and aboveground tissues, as well as the metal partitioning between cellular fractions (soluble and insoluble) in four different species (Triglochin maritima L., Juncus maritimus Lam, Sarcocornia perennis (Miller) A.J. Scott, and Halimione portulacoides (L.) Aellen) was assessed. Mercury accumulation, translocation and compartmentation between organs and cellular fractions were related to the plant species.Results showed that the degree of Hg absorption and retention was influenced both by environmental parameters and metal translocation/partitioning strategies. Different plant species presented different allocation patterns, with marked differences between monocots (T. maritima and J. maritimus) and dicots (S. perennis, H. portulacoides). Overall, the two monocots, in particular T. maritima showed higher Hg retention in the belowground organs whereas the dicots, particularly S. perennis presented a more pronounced translocation to the aboveground tissues. Considering cellular Hg partitioning, all species showed a higher Hg binding to cell walls and membranes rather than in the soluble fractions. This strategy can be related to the high degree of tolerance observed in the studied species. These results indicate that the composition of salt marsh plant communities can be very important in dictating the Hg mobility within the marsh ecosystem and in the rest of the aquatic system as well as providing important insights to future phytoremediation approaches in Hg contaminated salt marshes. 相似文献
60.