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排序方式: 共有1039条查询结果,搜索用时 468 毫秒
931.
G. C. M. L. Christiaens J. C. Oosterwijk R. H. Stigter P. P. Deutz-Terlouw A. L. J. Kneppers E. Bakker 《黑龙江环境通报》1994,14(1):51-55
Two twin pregnancies at risk for a sex-linked disorder are described. Both pregnancies were dichorionic. Transabdominal sampling was chosen for prenatal diagnosis. Molecular genetic techniques raised suspicion with regard to the accuracy of the samples in one case. Second-trimester amniocentesis confirmed the error. Selective feticide of the affected fetus was performed. When first-trimester prenatal diagnosis is offered in dichorionic twin pregnancies, confirmation through molecular genetic testing can confirm that villi have been obtained from different fetuses. All parties must be aware that additional invasive diagnostic procedures in the second trimester may be required in cases of doubt. 相似文献
932.
Detection of trisomy 2 and trisomy 16 mosaicism through chorionic villus sampling (CVS) is not an infrequent finding. We describe here two cases, one of non-mosaic trisomy 2 and the other of high level mosaicism for trisorny 16. Amniocentesis in both cases demonstrated non-mosaic 46,XY karyotypes. Each pregnancy continued to delivery of liveborn, normal-appearing boys; both pregnancies were complicated by severe intrauterine growth retardation (IUGR). Postnatal studies of placental biopsies in both cases confirmed the original CVS findings, whereas cord blood karyotypes were normal in both boys. Both children have demonstrated adequate catch-up growth. 相似文献
933.
Pure fetal blood, (uncontaminated with maternal blood), was obtained from two male fetuses at risk for X-linked mental retardation with fragile(X) at Xq27–28 by direct vision fetoscopy and fetal blood sampling. Both were shown to have this fragile site on the X chromosome while nine other fetal blood samples from pregnancies at risk for other X-linked diseases, or haemoglobinopathies did not show fragile sites at Xq27–28, and a blood sample from an abortus showed only 1 fragile site in 95 mitoses. Both pregnancies were terminated, cultures established from fetal tissues, and the diagnosis confirmed in each case. The problems of demonstrating the fragile site in tissues other than fetal blood in these pregnancies (such as amniotic fluid cells or fibroblasts from fetal tissues) are discussed. 相似文献
934.
935.
Dr. D. F. Callen G. Korban G. Dawson L. Gugasyan E. J. M. Krumins S. Eichenbaum J. Petrass S. Purvis-Smith A. Smith G. Den Dulk N. Martin 《黑龙江环境通报》1988,8(6):453-460
From a total of 1312 diagnostic chorionic villus samplings (CVS) there were 22 which showed discordance between the karyotype of the chorionic villi and that of the fetus. This frequency was some 20-fold higher than that reported at amniocentesis. In the majority of discordant cases, the fetal karyotype was normal while the placenta! karyotype was mosaic. In four cases, the placenta! karyotype was non-mosaic (a trisomy 16, a monosomy X, and two tetraploids) while the fetal karyotype was normal. In one case, the placenta was trisomy 18 while the fetus was mosaic. There were two ‘false-negative’ results where short-term methods showed only normal cells while both long-term cultures of chorionic villi and fetal cells were mosaic, in one 46,XY/47.XXY and in the other 46,X Y/47.X Y, + 21. 相似文献
936.
Steen Smidt-Jensen M.D. Niels Hahnemann Jalil Hariri Peter K. A. Jensen Aage J. Therkelsen 《黑龙江环境通报》1986,6(2):125-132
A consecutive series of 26 women followed to term after first trimester transabdominal chorionic villi sampling is presented. The clinical application of transabdominal chorionic villi sampling (TA-CVS) seems to have certain advantages, especially from the patients' point of view, but also in regard to successful sampling and to the complication ratio. The results in this clinical trial revealed no cases of abortions, no signs of placental damage and no cases of vaginal bleeding or infections. 相似文献
937.
In 226 women requesting chorionic villus sampling (CVS), routine cervical cultures were obtained before the procedure. Transcervical CVS was performed irrespective of the test results. The prevalence of potential pathogens in cervical cultures at our institution is low. Beta haemolytic Streptococcus was cultured in 3 per cent of the women. No pathogenic microorganisms were isolated in 64 per cent of the women. There was no relationship between culture results and the outcome of pregnancy. These observations suggest that adequate antiseptic cleansing of the genital tract is a suitable approach and there is no need to routinely perform cultures before CVS. 相似文献
938.
CHRISTOPHER K. Wikle L. Mark Berliner Noel Cressie 《Environmental and Ecological Statistics》1998,5(2):117-154
Space-time data are ubiquitous in the environmental sciences. Often, as is the case with atmo- spheric and oceanographic processes, these data contain many different scales of spatial and temporal variability. Such data are often non-stationary in space and time and may involve many observation/prediction locations. These factors can limit the effectiveness of traditional space- time statistical models and methods. In this article, we propose the use of hierarchical space-time models to achieve more flexible models and methods for the analysis of environmental data distributed in space and time. The first stage of the hierarchical model specifies a measurement- error process for the observational data in terms of some 'state' process. The second stage allows for site-specific time series models for this state variable. This stage includes large-scale (e.g. seasonal) variability plus a space-time dynamic process for the anomalies'. Much of our interest is with this anomaly proc ess. In the third stage, the parameters of these time series models, which are distributed in space, are themselves given a joint distribution with spatial dependence (Markov random fields). The Bayesian formulation is completed in the last two stages by speci- fying priors on parameters. We implement the model in a Markov chain Monte Carlo framework and apply it to an atmospheric data set of monthly maximum temperature. 相似文献
939.
Comparison between Hansen-Hurwitz and Horvitz-Thompson estimators for adaptive cluster sampling 总被引:1,自引:0,他引:1
Mohammad M. Salehi 《Environmental and Ecological Statistics》2003,10(1):115-127
Thompson (1990) introduced the adaptive cluster sampling design. This sampling design has been shown to be a useful sampling method for parameter estimation of a clustered and scattered population (Roesch, 1993; Smith et al., 1995; Thompson and Seber, 1996). Two estimators, the modified Hansen-Hurwitz (HH) and Horvitz-Thompson (HT) estimators, are available to estimate the mean or total of a population. Empirical results from previous researches indicate that the modified HT estimator has smaller variance than the modified HH estimator. We analytically compare the properties of these two estimators. Some results are obtained in favor of the modified HT estimator so that practitioners are strongly recommended to use the HT estimator despite easiness of computations for the HH estimator. 相似文献
940.
四川省农用土地资源卫星遥感宏观监测技术方法研究 总被引:6,自引:1,他引:6
通过对土地利用类型区的分层技术、卫星遥感抽样技术、样方调查方法、数据库建立、数据汇总与外推方法、数理统计分析与精度评估等6个专题的重点研究,探索出一套四川省农用土地利用现状卫星遥感抽样调查与监测的技术方法。该技术方法实用性和可操作性较强,已在四川省实施应用,完成了1∶10万农用土地利用现状抽样调查。土地利用类型区分为7个层25个亚层,抽样数为118个,样方大小为10km×10km(即100km2),实际抽样率为2.0%。应用结果表明:在合理分层的基础上,采用卫星遥感抽样与地理信息系统相结合的方法,能满足土地利用现状宏观调查与监测的精度要求。 相似文献