Bromination of selected pharmaceuticals in water matrices

The bromination of five selected pharmaceuticals (metoprolol, naproxen, amoxicillin, phenacetin, and hydrochlorothiazide) was studied with these compounds individually dissolved in ultra-pure water. The apparent rate constants for the bromination reaction were determined as a function of the pH, obtaining the sequence amoxicillin > naproxen ? hydrochlorothiazide ≈ phenacetin ≈ metoprolol. A kinetic mechanism specifying the dissociation reactions and the species formed for each compound according to its pK_a value and the pH allowed the intrinsic rate constants to be determined for each elementary reaction. There was fairly good agreement between the experimental and calculated values of the apparent rate constants, confirming the goodness of the proposed reaction mechanism.In a second stage, the bromination of the selected pharmaceuticals simultaneously dissolved in three water matrices (a groundwater, a surface water from a public reservoir, and a secondary effluent from a WWTP) was investigated. The pharmaceutical elimination trend agreed with the previously determined rate constants. The influence of the main operating conditions (pH, initial bromine dose, and characteristics of the water matrix) on the degradation of the pharmaceuticals was established. An elimination concentration profile for each pharmaceutical in the water matrices was proposed based on the use of the previously evaluated apparent rate constants, and the theoretical results agreed satisfactorily with experiment. Finally, chlorination experiments performed in the presence of bromide showed that low bromide concentrations slightly accelerate the oxidation of the selected pharmaceuticals during chlorine disinfection.     

Partitioning behaviour of perfluorinated alkyl contaminants between water, sediment and fish in the Orge River (nearby Paris, France)

This paper reports on the partitioning behaviour of 15 perfluorinated compounds (PFCs), including C₄-C₁₀ sulfonates and C₅-C₁₄ carboxylic acids, between water, sediment and fish (European chub, Leuciscus cephalus) in the Orge River (nearby Paris). Total PFC levels were 73.0 ± 3.0 ng L⁻¹ in water and 8.4 ± 0.5 ng g⁻¹ in sediment. They were in the range 43.1-4997.2 ng g⁻¹ in fish, in which PFC tissue distribution followed the order plasma > liver > gills > gonads > muscle. Sediment-water distribution coefficients (log K_d) and bioaccumulation factors (log BAF) were in the range 0.8-4.3 and 0.9-6.7, respectively. Both distribution coefficients positively correlated with perfluoroalkyl chain length. Field-based biota-sediment accumulation factors (BSAFs) are also reported, for the first time for PFCs other than perfluorooctane sulfonate. log BSAF ranged between −1.3 and 1.5 and was negatively correlated with the perfluoroalkyl chain length in the case of carboxylic acids.     

Road deicing salt irreversibly disrupts osmoregulation of salamander egg clutches

It has been postulated that road deicing salts are sufficiently diluted by spring rains to ameliorate any physiological impacts to amphibians breeding in wetlands near roads. We tested this conjecture by exposing clutches of the spotted salamander (Ambystoma maculatum) to three chloride concentrations (1 mg/L, 145 mg/L, 945 mg/L) for nine days, then transferred clutches to control water for nine days, and measured change in mass at three-day intervals. We measured mass change because water uptake by clutches reduces risks to embryos associated with freezing, predation, and disease. Clutches in controls sequestered water asymptotically. Those in the moderate concentrations lost 18% mass initially and regained 14% after transfer to control water. Clutches in high concentration lost 33% mass and then lost an additional 8% after transfer. Our results suggest that spring rains do not ameliorate the effects of deicing salts in wetlands with extremely high chloride concentrations.     

湖北省降水分区研究

利用湖北省19个国家级气象台站1956~2009年逐月降水资料,采用分层聚类方法,基于聚类分析碎石图和聚类树状图来探索最适宜的分区方案,对湖北省全年、逐月降水进行了分区,并结合西太平洋副热带高压的移动探讨了分区的合理性,之后逐区进行了自相关分析和趋势分析。结果表明：湖北省全年降水分区为5区,1~12月降水分区分别为3、3、4、3、5、4、3、3、3、4、3、3个区。各月降水分区的差异性与西太平洋副热带高压的南北移动有密切关系,副高脊线在北纬18°以南、北纬20°以北,以及缓慢南退过程中,分区形式有较大差异。自相关分析以及趋势分析结果表明单一气象站不能代表所在分区的气候特点,而所在分区又不能代表湖北省的气候特点,基于不同目的,进行分区和综合,将有助于研究特定区域的气候特点     

基于网格划分的宜兴市区滨水区可达性评价

城市滨水区可达性不仅仅是空间距离的阻隔,还包括人们对滨水空间的需求及滨水区自身对公众的吸引力。依据潜能模型的概念,选取人口密度、滨水区综合质量和以土地利用表达的交通作为评价因子,借助ArcGIS93软件,建立了基于网格划分的滨水区可达性计算模型。该模型通过对研究区域进行等距网格划分以及定量计算网格内的人口密度、最小阻力成本和滨水区综合质量来进行滨水区可达性的定量评价。运用该模型评价了宜兴市中心城区居民至各滨水区的可达性水平,发现各滨水区平均可达性水平存在明显差异,最高的是团氿,最低的是蠡河;对每个滨水区而言,可达性从空间上均呈现出以滨水区为中心由内向外递减的趋势。评价结果可为城市滨水区合理建设格局的制定和居民享用滨水区的公平性提供决策参考     

基于WebGIS三峡干流水质模拟平台研究

三峡蓄水成库后仍属于典型的河道型水库,其总体水流、水质运动特性符合一维水流水质运动规律。针对三峡库区总体水流、水质运动特性,采用一维水流水质模型对三峡库区水流和水质进行了模拟。以该模型为核心,利用Web Services技术开发并在互联网上发布了模型服务,在此基础上采用成熟的WebGIS和富客户端Flex等技术构建了适用于三峡库区的干流水质模拟平台;能够实现包括各计算断面流速、流量、水位以及污染物浓度时空过程在内的三峡库区干流流速场和浓度场的数值模拟。以库区干流清溪场至十里铺断面内的江段作为模拟实例,利用该平台模拟计算江段内水流和水质状况,并以水文水质同步观测数据对模拟结果进行验证,结果表明其具有较好的模拟效果;为三峡库区污染物总体输移扩散特性研究提供了有利工具,同时也为国家和地方政府进行库区水环境决策提供了技术支持     

基于控制单元的水环境容量核算研究——以锦江流域为例

水环境容量核算是流域水环境容量总量分配的重要依据,关系到流域水质目标的实现。控制单元作为流域水环境管理的一个基本实施单位,以其为基础开展水环境容量核算,对于科学制定控制单元容量总量分配具有重要意义。以江西省锦江流域为例,根据水环境容量核算的基本原理,结合锦江流域的污染状况、水质现状和水环境功能区划,对流域各控制单元COD和氨氮的水环境容量进行分析,结果表明,控制单元的水环境容量与其内排污口的分布及功能区水质目标密切相关,COD的水环境容量以高安控制单元的最大,为 21 811 t/a;其次为上宜控制单元,为 21 168 t/a;再次为新丰控制单元,为 14 493 t/a;万载控制单元的最小,为 7 607 t/a。氨氮的水环境容量在各控制单元的分布特征与COD的略有不同,以上宜控制单元的最大,为790 t/a;其次为高安控制单元,为664 t/a;再次为新丰控制单元,为462 t/a;万载控制单元的最小,为303 t/a     

The Comparative Approach on Outdoor Leisure Behavior of Urban Elderly People： A Case Study in Beijing

With the income increase of elderly people in Beijing and the improvement of leisure facilities since 2000, the quality of elderly people leisure life in Beijing has obviously increased com- pared to t...     

Population Growth, Available Resources, and Quality of Life： China＇s Post-Reform Economic Development

Two opposing intellectual traditions and their contem- porary developments regarding the relations among population, available resources, and quality of life as reflected in economic growth are reviewe...     

自然灾害社会脆弱性评估研究——以上海市为例

基于投影寻踪聚类模型(PPC),结合基于实数编码的加速遗传算法(RAGA),对上海市进行了自然灾害社会脆弱性评估的尝试。结果表明:①灾害社会脆弱性最高的为崇明县,其次为宝山区和金山区;②灾害社会脆弱性最低的是黄埔区,其次是徐汇区和静安区;③总体而言,灾害脆弱性较低的地区集中于上海城市中心区,而城市边缘区的社会脆弱性一般较高。