垃圾填埋场渗滤液对小鼠遗传毒性和肝肾功能的影响

对垃圾填埋过程中产生的渗滤液的遗传毒性及其对肝肾功能的影响进行了初步研究. 选用经口急性毒性试验和微核试验,以某垃圾卫生填埋场2005年11月渗滤液为受试物,ICR纯种小鼠为受试对象,设置高、中、低3个浓度(即渗滤液原液,10倍稀释液和100倍稀释液)渗滤液染毒组和对照组,取小鼠眼静脉血测定总胆红素(TBIL)、谷丙转氨酶(ALT)、谷草转氨酶(AST) 、血清肌酐(Cr)和血尿酸氮(BUN)5项生化指标,探讨渗滤液诱发小鼠肝肾及遗传损伤. 结果表明,高、中浓度组小鼠骨髓嗜多染红细胞的微核率分别为18.8‰和3.8‰,与阴性对照组相比,2组的微核率显著增加(n10,P<0.05). 血清生化分析表明,中、高浓度组谷丙转氨酶(ALT)分别为70.4和70.0 U/L,与对照组差异显著(P<0.05);渗滤液低、中、高浓度组谷草转氨酶(AST)分别为247.1,255.1和281.6 U/L,与对照组相比,3个浓度组的差别均具有统计学意义(P<0.01).整体动物试验水平表明,渗滤液可能对哺乳动物具有遗传损伤效应,对肝功能也可能会产生一定的影响.      

Modelling and optimisation of a product recovery network

An appropriate logistics network is an important element of the infrastructure of any product recovery company. Small and medium enterprises (SMEs) constitute a major fraction of the product recovery industry with a different business objective and scale of operation from those of original equipment manufacturers. This paper addresses the network design issues for SMEs involved in product recovery activities. A mathematical formulation is presented in an SME context and a subsequent simulation model is developed. A genetic algorithm approach is presented for optimising the network for a single product scenario.     

基于变权重和信息熵的区域水资源安全投影寻踪评价模型

区域水资源安全评价是气候变化下区域水安全管理的一项重要调控措施。为合理确定各评价指标的权重,提出了把权重结构分解为评价指标的单样本权重和样本集权重的新观点,建立了用基于加速遗传算法的模糊层次分析法和最小相对信息熵原理确定单样本权重、用基于加速遗传算法的投影寻踪模型和最大信息熵原理确定样本集权重的新模型--基于变权重和信息熵的投影寻踪评价模型（CWE PP）。将CWE PP模型应用于全国水资源安全背景下的巢湖流域水资源安全评价,结果表明：巢湖流域水资源安全状况整体上介于重度缺水与中度缺水之间,偏向重度缺水,略低于安徽省水资源安全状况。用CWE PP进行区域水资源安全评价,物理概念明确,计算结果合理,方法通用,在资源与环境综合评价中具有一定的推广应用价值。     

The hypothesis of hydrochorous dissemination of populations of conifers

A comparative analysis of field observations and experiments on the distance and rate of dispersal of self-sown Scotch pine (Pinus sylvestris L.) and Norway spruce (Picea abies (L.) Karst.) progeny has shown that the rate of their hydrochorous dissemination downstream is an order of magnitude higher than the rate of dispersal in upland areas. A hypothesis assigning priority to the role of hydrochory in the expansion of conifer populations to the tundra (periglacial) zone along with climate warming has been formulated and substantiated by comparative isozyme analysis of populations in transects lying along and across rivers.     

Elevation-dependent genetic variation of plants and seed embryos in the Crimea Mountain population of Pinus pallasiana D. Don

In the Crimea Mountain population of Pinus pallasiana D. Don, the genetic structure of adult plants and embryos was studied along an elevation gradient (150, 400, 600, and 900 m a.s.l.). Ten polymorphic loci of six enzyme systems were examined. The degree of differentiation of plants from different elevations and their progeny with respect to genetic structure proved to be low, indicating the absence of strict isolation barriers that would interfere with gene flow along the elevation gradient.     

Resilience-based approach to safety barrier performance assessment in process facilities

The performance assessment of safety barriers is essential to find vulnerable elements in a safety barrier system. Traditional performance assessment approaches mainly focus on using several static indicators for quantifying the performance of safety barriers. However, with the increasing complexity of the system, emerging hazards are highly uncertain, making it challenging for the static indicators to assess the performance of safety barriers. This paper proposes a resilience−based performance assessment method for safety barriers to overcome this problem. Safety barriers are classified according to their functions first. The dynamic Bayesian network (DBN) is then introduced to calculate the availability function under normal and disruption conditions. The ratio of the system's availability, when affected by the disruption, to the initial availability, is used to determine the absorption capacity of the system. The ratio of the quantity of availability recovery to the total quantity of system represents the adaptation and restoration capacity of the system. The system's resilience is represented by the sum of absorption, adaptation, and restoration capacities. The wax oil hydrogenation process is used to demonstrate the applicability of the proposed methodology.     

基于自适应遗传算法的应急物资储备库选址及物资调配优化研究

应急物资储备库是应急救援的重要载体,储备库选址是否科学合理决定着整个应急公共服务体系的成效,而传统遗传算法在研究储备库选址与物资调配相结合的问题上存在局限性。针对这一问题,从需求点及应急设施服务质量视角构建基于覆盖满意度和经济性的应急设施选址与物资调配优化模型,并根据模型设计自适应遗传算法(AGA),结合储备库实际情况采取具有方向性的初始群体生成法提高搜索速度,设计自适应交叉与变异算子使AGA能够在进化速度与解的质量之间进行权衡,并获得全局最优解。结果表明,该算法能跳出局部最优从而获得最优的选址-分配方案,可为应急管理部门和决策机构的应急设施选址规划及应急物资分配提供理论依据和决策参考。