城市人居环境生态评估方法探索——以南通市为例

以南通市为例,探索宏观层面的城市人居环境生态评估方法.通过统计、整理南通市人居环境数据资料,建立城市人居环境宏观评估模型及其评估指标体系(共25项指标),进而分析并评价南通市人居环境整体现状.     

Chromosome 18 analysis by fluorescence in situ hybridization (fish) in human blastomeres of abnormal embryos after in vitro fertilization (ivf) attempt

We performed fluorescence in situ hybridization (FISH) with a chromosome 18-specific probe on human abnormal cleaved embryos, fertilized either by two spermatozoa and exhibiting three pronuclei (3 PN) or normally fertilized and exhibiting two pronuclei (2 PN) with subsequent severe fragmentation and/or blocking. The aim of the study was to evaluate the incidence of chromosome 18 anomalies among these embryos, in order to evaluate the FISH efficiency on such material and to obtain more precise and complete data than those obtained with classical cytogenetic analysis. For the 3 PN cleaved embryos, FISH confirmed the frequent regulation towards diploidy (25 per cent) and the high frequency of mosaics (53 per cent). For the 2 PN blocked or damaged embryos, FISH permitted chromosome evaluation, which was otherwise impossible with classical cytogenetic techniques: we also found a high mosaic frequency (45 per cent) with these embryos. If this frequency were the same for normally developing embryos, it would be a major obstacle to the reliability of either chromosomal or genetic preimplantation diagnosis.     

浅谈环境噪声的危害与控制

通过了解噪声的来源；具体分析了噪声对人体的危害，不同的噪声，级别不同，对人体的健康影响程度也不同，尤其是长期接触噪声的工作人员。如何有效地防治噪声，从噪声源、传播途径及个人防护方面进行了具体的分析。     

环境噪声污染对人体健康的影响

环境噪声污染污染对人体健康危害十分严重，除影响听力外，还可能引发神经，心血管，消化，内分泌及免疫系统疾病，且对视力，优生优育均有不同程度影响。加强环境噪声污染的防治，对于保障人民健康有重要意义。     

空气污染与人类健康

污染物质排入大气层后，对大气环境产生了污染，造成气候的改变，对人类的健康产生了影响。本文对人体吸入污染物质后所发生的反应过程及危害机理进行了讨论。     

Analysis of maternal serum alpha-fetoprotein and free beta human chorionic gonadotrophin in the first trimester: Implications for down's syndrome screening

The aim of this study was to determine the maternal population, pregnancy, serum alpha-fetoprotein (AFP) and free β subunit of human chorionic gonadotrophin (FβhCG) parameters in a large series of women attending prenatal clinics before 15 weeks' gestation and to assess the practical problems of population screening for Down's syndrome in the first trimester using these markers. Serum samples were collected from 8600 women attending prenatal clinic booking visits. Maternal serum AFP and FβhCG medians were calculated for each day of gestation (49–104 days), using both dates and ultrasound estimates of gestation. The effects of maternal weight, twin pregnancies, and threatened abortion on AFP and FβhCG levels were analysed. The median age of the population was 27.1 years and the median weight 62.1 kg. Twenty-six per cent of samples were collected before 70 days and 50 per cent before 78 days' gestation. Eighty-nine per cent of all samples had gestational estimates by dates, 60 per cent by ultrasound and 52 per cent by both dates and ultrasound. The AFP median was 5 kU/1 at 49 days, 5.9 kU/1 at 70 days, and 17.9 kU/1 at 100 days. The peak median FβhCG level was 66.4 ng/ml at 64 days, falling to 20.6 ng/ml at 100 days' gestation. Both AFP and FβhCG levels showed log Gaussian distributions but the standard deviation for AFP was 20 per cent greater than that found in the second trimester. AFP and FβhCG levels showed an inverse relationship with maternal weight and were increased in twin pregnancies (1.68 and 1.97 multiples of the median, respectively). AFP and FβhCG can be readily measured in a large screening population in the first trimester. Down's syndrome screening protocols based on these markers could be refined by the use of gestations in individual days but AFP is likely to be a less effective marker and detection rates are likely to be lower than in the second trimester. To realize the potential of first-trimester screening, more women should be encouraged to attend the prenatal clinic in early pregnancy and ultrasound dating should be carried out for all pregnancies at this stage.     

Analysis on reasons for the Yellow River''s dry-up and its eco-environmental impacts

The Yellow River, or Huanghe, is one of the most important river in China. It is the major water resources for north and northwest China. Since 1972, the Yellow River's dry-up has occurred frequently and become even more year by year. Except the huge loss to social life and economic development, the Yellow River's dry-up brings about great impacts to eco-environment. This paper analyzed the reasons and impacts from multi-aspect: effects of climate change, influence of human activities and impacts to delta's eco-environment, aquatic life resources, agricultural eco-environment, water pollution and flood prevention as well.     

环境质量资本税的征收与可持续发展

论述了社会进程中人类活动导致环境质量逐渐存在差异，其中相对优质的环境便具有了稀缺资源的性质，即“环境质量资源”。阐述了环境质量资源是重要的自然资本，指出环境质量资源稀缺是现代社会的基本特征，且这种稀缺不以现代人的意志为转移。着重论述了征收环境质量资本税对国家实施可持续发展的重大意义。     

The emergence of global environmental awareness

An effective plan for global ecosystem management must be developed in the next 10 or 20 years. Awareness of the need has recently emerged, but still no integrated resource management system is universally accepted. A fragmented management approach has not been effective. Any successful course of action must be based on three assumptions: (1) that science can determine how ecosystems function, (2) once this is known, the social/political system will be able to protect ecosystems to the extent needed for the survival of human society, and (3) reality will take precedence over political expediency because Mother Nature cannot be fooled. This discussion focuses on the transition from awareness to taking effective action.     

SO2体内衍生物对人血红细胞的氧化损伤及其防护

为了探讨二氧化硫(SO2)对哺乳类细胞的毒性作用及其防护.以SO2体内衍生物-亚硫酸盐和亚硫酸氢盐(分子比为3∶1)及抗坏血酸(维生素C,Vc)单独或同时处理人血红细胞,并测定红细胞过氧化氢酶(CAT)、超氧化物歧化酶(SOD)活性及脂质过氧化(LPO)水平.结果表明,SO2体内衍生物单独处理后,CAT和SOD活性均显著甚至极显著降低,而LPO水平均极显著升高.Vc单独处理后,CAT及SOD活性均有所升高,但差异不显著;而LPO水平除Vc为0.05 mmol·L-1剂量组外,其余各组均极显著降低.0.1 mmol·L-1Vc和不同剂量SO2衍生物共同处理后,Vc使各组CAT、SOD活性均有升高,且Vc也降低了SO2衍生物引起的人血红细胞LPO水平.由此认为,SO2体内衍生物可以使人血红细胞中CAT和SOD的活性降低、LPO水平增高,Vc可起到一定防护作用.