Cultured human-cell-based bioassay for environmental risk management

Among bioassays for evaluating various impacts of chemicalson humans and ecosystems, those based on culturedmammalian-cells can best predict acute lethal toxicity to humans. Weexpect them to be employed in the future in environmentalrisk management alongside mutagenicity tests and endocrine-disrupting activity tests. We recently developed adisposable bioassay device that immobilizes humanhepatocarcinoma cells in a small micropipette tip. Thisenables very quick (within 2 h) evaluation of acute lethaltoxicity to humans. For bioassay-based environmentalmanagement, 2 promising approaches have been demonstrated bythe US-EPA: toxicity identification evaluation (TIE) andtoxicity reduction evaluation (TRE). The Japanese Ministryof Environment has been supporting a multi-center validationproject, aimed at assembling a bioassay database. To makefull use of these resources, we present a numerical modelthat describes contribution of individual chemical toobserved toxicity. This will allow the selection of the mosteffective countermeasure to reduce the toxicity. Bioassay-based environmental risk management works retrospectively,whereas impact assessment using substance flow models andtoxicity databases works prospective. We expect that these 2approaches will exchange information, act complementarily,and work effectively in keeping our environment healthy inthe 21st century.     

Environmental Health Policy: Analytic “Framing” of the Great Lakes Picture

/ The International Joint Commission (IJC) has overseen the implementation of the Great Lakes Water Quality Agreement between Canada and the United States for 25 years. Part of its mandate has been to facilitate international cooperation among a diversity of stakeholders focusing on the "waters" and the "ecosystem." In the 1970s policy focused on phosphorus reduction and individual contaminants, with some efforts (after 1978) to take an ecosystem (ecological perspectives) approach. In the last 15 years human health effects from (real and perceived) environmental causes have received considerable recognition. By contrast, less concern has been expressed for what is traditionally considered "environment" issues (such as protecting fish species). This shift at the policy level is well illustrated in the manner in which human health is increasingly used as a way for mobilizing environmental agendas. This paper analyzes nine IJC biennial reports to track how the framing of Great Lakes issues has shifted from concern for its waters to concern for human neurobehavior and reproductive systems. Frame analysis is used to conceptualize the controversies that are expressed through the Great Lakes policy documents. The analysis of the reports also reveals a shift in operational frames, used by the IJC to mobilize decision-makers into action.     

欠发达城市人居环境评价体系构建及应用

在参阅国内城市人居环境评价指标体系研究的基础上，选择安徽省六安市为样区，提出了欠发达城市人居环境评价的原则、指标构成以及评价模式和方法。其中，指标体系共分为目标层、准则层、分类层和指标层4个层次，从居住建设、生态环境和社会经济三大系统构建了39个单项指标，依据六安市2005年的调查统计资料，对其人居环境的建设水平和满意度两方面进行了对比评价，验证结果科学可行，可为同类地区人居环境质量评价提供参考。     

混凝土结构施工中人因差错的模拟

以施工现场人因差错真实准确的调查实测数据为依据,笔者采用人的可靠性分析方法建立了混凝土结构施工中人因差错发生及其对混凝土强度影响规律的数学模型,并编制了相应的模拟计算程序。将该模拟计算程序所得的考虑人因差错的混凝土强度模拟计算结果与实测的混凝土强度调查结果进行比较,二者具有很好的一致性,说明该数学模型和模拟计算程序是比较符合实际的,也是比较合理的。上述模拟计算结果为考虑人因差错的结构安全性分析以及人因差错的有效控制措施研究提供了参考依据。     

核电站中处理人的行为问题的系统方法

引发事件的失误原因或者作为行为趋向的一部分统称为人的行为问题.总结出了核电站中处理人的行为问题的系统方法,即从问题的识别与描述、事件调研、原因分析到开发纠正行动这样一个过程.结合核电站实际,着重介绍了人误原因的识别,如根原因分析技术和起因树.     

HUMAN BEHAVIOR AND RESPONSE TOWARDS STORM HAZARD IN WEST VANCOUVER,BRITISH COLUMBIA1

ABSTRACT: Human behavior and response towards storm hazard are examined in this study. One-hundred and twenty flood victims in West Vancouver, British Columbia, were administered a sentence completion test to ascertain how these victims behaved and responded to the flash flood of July 12, 1972. The sentence completion test consisted of 11 sentence stems. Seven of these dealt with the respondent's behavior toward the storm experience, and four with the issue of internal vs. external locus of control. Completions of the seven sentence stems at three time situations showed that West Vancouverites expressed the normal reactions of fear and anxiety before the storm; showed negative emotions during the storm; and displayed a feeling of mutual cooperation after the storm. Completions of the remaining four sentence stems revealed that West Vancouverites emphasized the importance of internal factors, viz., autonomy, drive and hard work, in controlling their lives. They recognized God as a benevolent - protective and almighty - powerful figure. Forty percent of the respondents did not believe in luck, while 8 percent regarded it as important in their lives. One might conclude that West Vancouverites could cope with natural hazardous threats better than those who rely on external factors in directing their lives.     

INTERNATIONAL DECADE ON DRINKING WATER AND SANITATION1

ABSTRACT: The UN conference on Human Settlements (HABITAT) held in June 1976 at Vancouver, Canada, concluded that nearly two-thirds of the population of the developing world lacked access to safe drinking water and that a larger proportion lacked the means for hygienic human waste disposal. The conference urged governments to give priority to these two areas in their developement process. In March 1977, the UN Water Conference, held at Mar del Plata, Argentina, called for establishing the 1980's as the Decade for Drinking Water and Sanitation. The goal would be to bring clean water and sanitation to all peoples in the world by 1990. Since March 1979, four separate UN bodies have passed resolutions supporting the Decade and calling on all governments to support the Decade's goals. The U.S. Government, other OECD member states, and the private sector must combine to make this Decade a success.     

Public policy for the use of reclaimed water

This article documents the general need to reuse water reclaimed from sewage effluents for beneficial purposes and then considers in detail which specific uses will be most beneficial. The analysis begins by describing five levels of wastewater treatment: primary, secondary, tertiary, advanced, and advanced plus complete treatment. Next, five major uses for reclaimed water are identified: groundwater recharge, industrial use, irrigation, recreational lakes, and direct municipal reuse. Subcategories of reuse falling under each of the five major reuse categories are also identified and discussed. The analysis then proceeds to review significant literature available on health and environmental effects, treatment and distribution costs, and public opinion concerns in relation to each of the five major uses and their related subcategories. The paper concludes with a cumulative numerical analysis of the disbenefits associated with each specific type of reuse summed over the health effects, environmental effects, treatment costs, distribution costs, and public opinion concerns. Uses of reclaimed water for industrial purposes and for irrigation of fodder and fiber crops are found to be most beneficial by the analysis here employed, and use for aquifer recharge and direct municipal reuse are found to be least beneficial.     

Health and safety implications of alternative energy technologies. I. Geothermal and biomass

An evaluation of potential occupational and public health aspects of geopressure, hydrothermal, hot dry rock, silviculture, crop and animal residues, fermentable plant products, municipal waste, and plantation energy technologies has been performed. Future development of these energy options in the United States will contain hazards that could easily be eliminated by safer equipment design and common-sense attention to operation and maintenance. Occupational exposure to hydrogen sulfide gas occurs near all geothermal sites and wherever organic matter decomposes anaerobically. Respiratory damage has occurred to laborers in geothermal fields, while farm workers have been fatally overcome when employed near agitating liquid manure systems. However, the most frequent and severe of reported injuries to geothermal workers is dermal exposure to caustic sludges produced by H₂S abatement systems.Principal health and safety considerations of biomass pathways are directly related to the diffuse nature of solar energy fixation by photosynthesis and subsequent transfer to animal food chains. Since the potential fuel is in an unconcentrated form, cultivation, harvest, and transport are necessarily laborintensive. Thus, a significant potential for occupational injuries and fatalities exists. Of all biomass systems evaluated, direct burning of solid fuels presents the greatest public health risk. Data are presented to characterize the population at risk and the frequency and severity of injuries.Operated by Union Carbide Corporation under contract W-7405-eng-26 with the U.S. Department of Energy.     

Book Reviews

Books reviewed:
Thomas Drabek, Disaster-induced Employee Evacuation
Hugh Brammer, Agricultural Disaster Management in Bangladesh
Boris Porfiriev, Disaster Planning and Emergency Management in Russia
Patrick Bracken and Celia Petty, eds, Rethinking the Trauma of War
R. Cohen and F. M. Deng, eds, The Forsaken People: Case Studies of the Internally Displaced
Tom Trier and Lars Funch Hansen, eds, Conflict and Forced Displacement in the Caucasus: Perspectives, Challenges and Responses