Low dose effects and non-monotonic dose responses for endocrine active chemicals: Science to practice workshop: Workshop summary

A workshop was held in Berlin September 12–14th 2012 to assess the state of the science of the data supporting low dose effects and non-monotonic dose responses (“low dose hypothesis”) for chemicals with endocrine activity (endocrine disrupting chemicals or EDCs). This workshop consisted of lectures to present the current state of the science of EDC action and also the risk assessment process. These lectures were followed by breakout sessions to integrate scientists from various backgrounds to discuss in an open and unbiased manner the data supporting the “low dose hypothesis”. While no consensus was reached the robust discussions were helpful to inform both basic scientists and risk assessors on all the issues. There were a number of important ideas developed to help continue the discussion and improve communication over the next few years.     

试论我国化学品测试GLP实验室建设

在介绍了GLP及GLP实验室之渊源的基础上,从化学品贸易的国际性特点,制定和执行化学品环境管理的法律法规要求,以及我国化学品环境管理的实际需要三方面论述了建设我国化学品测试GLP实验室的必要性;并从行动依据?理论准备?硬件能力状况?化学品测试技术服务的市场需求出发,分析和论证了建设我国化学品测试GLP实验室的可行性?认为建设我国化学品测试GLP实验室的当务之急是要加快化学物质环境管理立法;尽早制定严格的科学的审查监督办法;集中力量,重点建设;迅速完成由理论到实践的转变?具体建设中应注意充分利用国内现有的技术力量和国外的经验与帮助,稳步滚动发展?      

化学品测试GLP实验室考核评估体系研究

通过对国内外实验室认可工作的分析比较,提出了我国化学品测试GLP实验室的考核评估体系框架构成的3条原则:趋同性、高标准和可操作性。笔者认为我国化学品测试GLP实验室考核评估体系应包括:实验室认可管理办法、认可准则、认可程序、认可后扩充项目的程序、评审细则、评审员管理办法、认可申请书、评审报告。并对该体系的具体构成进行了阐述。      

陕西关中地区土地资源的优化配置

从分析陕西省关中地区土地资源利用现状结构特征及存在问题入手,运用灰色线性规划模型对土地利用结构进行优化配置。模型选取多个影响土地利用结构因子,并通过预测未来关中地区各行各业之用地需求及用地限制从而确定出各因子适当参数,进行模拟后得出典型备选方案。最后从综合效益及可行性双方面考虑,经层次分析法择出未来关中地区最优土地利用决策方案。