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N. Villa P. Riva D. Colombo E. Sala S. Mariani C. Zorloni F. Crosti L. Dalprà 《黑龙江环境通报》2001,21(10):801-805
The identification of small supernumerary marker chromosomes (SMCs) and the elucidation of their clinical significance remain two of the problems in classical human cytogenetics. We observed a small supernumerary ring in amniotic fluid cell cultures and identified its origin as r(2)(p10q11.2) and its extent by means of fluorescent in situ hybridisation (FISH). Uniparental disomy (UPD) was excluded by microsatellite analysis using polymorphic markers localised in the same region. On the basis of normal ultrasonographic checks, the patient decided to continue the pregnancy. A normal female was delivered at term and subsequent neonatal follow-ups confirmed the normal phenotype and development. In the present case, genetic counselling was not helpful because of the absence of reference cases. Detailed characterisation made it possible to correlate the normal baby phenotype with the trisomic 2p10-2q11.2 genomic region. Further molecular cytogenetic investigations of SMCs classified by DNA content and pregnancy outcome data should improve genetic counselling and risk evaluation. Copyright © 2001 John Wiley & Sons, Ltd. 相似文献
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Ying Zhi Xu 《中国人口.资源与环境(英文版)》2015,13(3):198-205
In an open economy, embodied carbon dioxide emissions in international trade should be taken into consideration to scientifically define each country’s emissions responsibility. In this study, a multiregional input–output model is constructed to calculate the embodied carbon dioxide emissions of 25 World Trade Organization members, including China, according to the producer–consumer shared responsibility principle. The study indicates that: it is fairer and more efficient to identify each country’s carbon dioxide emissions responsibility according to the shared responsibility principle; China’s producer responsibility is 1.4 times that of the USA, while China’s consumer responsibility is only one-tenth that of the USA; according to the producer responsibility principle, China shoulders the greatest responsibility. According to the producer–consumer shared responsibility principle, China’s responsibility shows a large decrease. Resource endowment, economic development stage, and trade structure account for the abovementioned changes in China’s emissions responsibility. 相似文献
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《Journal of Manufacturing Processes》2014,16(1):26-55
Welding is a fabrication process to join two different materials. Among the many welding processes, the arc and laser welding processes are the most widely used. Great effort is required to understand the physical phenomena of arc and laser welding due to the complex behaviors which include liquid phase, solid phase and, gas phase. So it is necessary to conduct numerical simulation to understand the detailed procedures of welding. This paper will present the various numerical simulation methods of the arc welding processes such as arc plasma, gas tungsten arc welding, gas metal arc welding, laser welding, and laser–arc hybrid welding. These simulations are conducted by the finite element method, finite differential method and volume of fluid method to describe and analyze the various welding processes. 相似文献
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《Environmental engineering science》2011,28(12):827-833
Abstract Catalytic incineration of toluene over γ-Al2O3-supported copper–manganese oxide catalysts in the temperature range of 433?K–553?K was investigated using a fixed-bed flow reactor. Catalysts were characterized using Brunauer-Emmett-Teller surface area analysis, scanning electron microscopy, temperature-programmed reduction, temperature-programmed oxidation, X-ray photoelectron spectroscopy, and X-ray diffraction. Incineration of toluene was achieved at temperatures up to 553?K and it was found that the weight ratio of reactants (Cu:Mn) was optimized to be 15:10. Brunauer-Emmett-Teller surface area results had no correlation with the activity of the catalysts. Results of temperature-programmed reduction/temperature-programmed oxidation and X-ray photoelectron spectroscopy showed that the redox peak of the 15Cu-10Mn catalyst shifted at lower temperatures and the binding energy shifted toward higher oxidation levels. These results show that high binding energy and high redox capacity are the causes of... 相似文献
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Water security is arguably the single most important factor regarding the future sustainability of our planet. Without water we have no life, and with depleting freshwater resources conflict can easily ensue. The intersection between hydrology and politics requires a delicate balancing from decision-makers to ensure policy is well-informed and science is well communicated. In this paper, we discuss water issues currently faced by Nepal, a nation where freshwater resources are abundant yet political pressures are threatening future water security. We argue that despite adequate water supplies a nation may still experience severe water insecurity, particularly if effective governance and equitable access are not prioritised. We explore potential policy options necessary to achieve a holistic framework for water resources management, which we suggest, need to consider water resource reliability, accessibility and governance as fundamental pillars for ensuring water security. 相似文献
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