沁海煤矿瓦斯重大灾害及生产动态安全状况诊断

按照《煤矿安全规程》2010版制成安全检查表,运用安全检查表法和系统分析的方法对煤矿的主要系统存在的隐患进行逐项诊断,主要诊断矿井的瓦斯抽放系统、矿井的通风系统、矿井的防尘系统、矿井的防灭火系统以及矿井运输提升系统等。诊断主要是针对瓦斯重大灾害及矿井生产过程中违章违规现象以及矿井自然属性带来的系统固有隐患,对矿井中员工的操作规范情况也进行检查,并对存在的隐患和员工的错误操作提出相应的整改措施,促使煤矿及时对矿井存在的系统固有隐患和人为隐患进行整改,以消除在生产动态过程中查出的隐患,从而预防煤矿事故的发生。消灭了事故隐患,实际上也是把事故消灭在萌芽状态之中,达到防患于未然,提高我国煤矿安全生产水平。     

基于理想点法的盾构隧道管片上浮致伤诊断

为定量化评估盾构隧道施工过程中管片上浮给隧道造成的损伤,作者提出将常见的损伤分为管片间变形、管片裂缝、管片表面剥落、沉降、渗漏水、断面整体变形、螺栓受到过大剪力以及管片受到过大水土压力等8大类。采用相关系数法选取15个底层指标,建立管片上浮致伤诊断指标体系。通过模糊变换对全部底层指标进行量纲一化处理,结合提出的融合赋权方法,构建管片上浮致伤诊断模型。最后,基于理想点法对中国湖南某盾构隧道管片上浮致伤情况进行诊断研究。结果表明,模型能有效评估管片上浮对隧道造成的损伤,诊断结果与工程实际情况及专家论证结果基本相符。     

Does nuchal translucency have a role in fetal cardiac screening?

Increased nuchal translucency is the strongest single marker for chromosomal abnormality. Consequently, it is currently becoming established as the foundation of most early screening programmes for Down syndrome. In the absence of chromosomal abnormality, increased nuchal translucency has been shown to be associated with other congenital anomalies including cardiac defects. Several datasets have now reported this association and here these are reviewed to assess the effectiveness of nuchal translucency measurement as a screening tool for the prenatal detection of congenital heart disease. Copyright © 2004 John Wiley & Sons, Ltd.     

Double-outlet right ventricle with absent left ventricle and mitral atresia in a fetus with a deletion 22q12

Interstitial deletions of chromosomal region 22q12 are rare. We report the prenatal diagnosis of a de novo interstitial deletion 22q12. The fetus was karyotyped because of a complex cardiac anomaly. Conventional and molecular cytogenetics showed a female karyotype with a de novo pericentric inversion of one chromosome 22 associated with a deletion of the chromosomal region 22q12 leading to a partial monosomy 22q12. At autopsy, the fetus showed double-outlet right ventricle (DORV) with absent left ventricle and mitral atresia. This observation suggests that one or several genes for the early looping step of heart development may reside in chromosomal region 22q12. Further studies are needed to identify these genes, and to search microdeletions of 22q12 region in patients with DORV. Copyright © 2004 John Wiley & Sons, Ltd.