基于皮电、心率和β波的指挥人员应急能力度量

指挥人员的应急能力是决定应急工作效率的重要因素,按照生理、心理性指标度量的指挥人员的应急能力,是选择指挥人员的重要依据之一。首先,分析指挥人员应急能力与情绪、生理性应激的关系。然后,利用E-prime软件,通过情绪Stroop效应范式诱发情绪,用生物反馈仪测量生理性应激状态下生理指标变化,研究高应急能力指挥人员应具备的能力条件。试验结果表明,高应急能力组人员应激前后皮电、心率、β波以及反应时间等指标变化率显著低于低应急能力组人员。试验结果与人的应急能力分类指标相符,能力较强的指挥人员的生理指标变化率较低,适合从事应急指挥方面的工作。     

Assessment of DNA damage and cytotoxicity of palmatine on human skin epithelial carcinoma cells

The present investigation was carried out to examine the cytotoxic and genotoxic effects of a Tinospora cordifolia crude methanolic extract (palmatine) on human skin epithelial carcinoma cells (A431). T. cordifolia is one of the indispensable medicinal plants used in Ayurvedic medicine for treatment of various diseases and recommended for improving the immune system. Cytotoxicity and genotoxicity evaluation was carried out using A431 cells treated with different concentrations of palmatine. The duration of the treatment was 24 and 48 hr. A cellular proliferative capacity test showed that palmatine produced cytotoxicity in concentration- and time-dependent manner. Further, palmatine induced significant intracellular reactive oxygen species generation and elevated lipid peroxidation, as well as activities of catalase and superoxide dismutase. DNA fragmentation analysis using the comet assay showed that palmatine induced genotoxicity in a concentration- and time-dependent manner. Evidence indicates palmatine is capable of induction of oxidative stress resulting in cell death and genomic instability.     

Prenatal diagnosis of congenital non-bullous ichthyosiform erythroderma (lamellar ichthyosis)

We report the first positive prenatal diagnosis ofcongenital non-bullous ichthyosiform erythroderma or lamellar ichthyosis. Fetal skin samples were obtained by fetoscopy at 21 weeks' gestation and examined by light and electron microscopy. Light microscopy revealed a thickened interfollicular epidermis with multiple layers of flattened cells and excessive keratinization of the epidermal lining of the follicular infundibulum. Electron microscopy of the thickened epidermis revealed granular cells that contained larger-than-normal keratohyalin granules and multiple layers of parakeratotic cornified cells. Although there was regional variation in the degree of interfollicular keratinization, follicles from all regions showed greater and more complete keratinization, indicating that they express the abnormality early enough in development to permit prenatal diagnosis at about 20 weeks' gestation.     

内嵌式蒙皮散热器气动阻力影响研究

目的 开展内嵌式蒙皮散热器对小型飞行器气动阻力影响研究,探明气动阻力产生的原因及影响因素。方法 利用数值仿真技术,对气动阻力增大的诱因进行理论分析,分别研究蒙皮散热器引流口半径、导流口半径和翅片厚度等结构参数对飞行器气动阻力及散热性能的影响,进而平衡蒙皮散热器散热能力和飞行器气动阻力等设计指标。结果 配置蒙皮散热器为电子设备提供热沉会导致小型飞行器气动阻力增大,原因是配置散热器诱导产生了额外的压差阻力和摩擦阻力。结论 增大引流口、导流口半径可减小压差阻力,增加翅片厚度,则可减小摩擦阻力,进而减小飞行器气动阻力。增加翅片厚度,可使气动阻力减少20%以上,同时也会导致传热性能的显著降低,增大引流口、导流口半径则可在一定程度促进传热。     

单桩负摩阻力计算方法比较分析

桩基工程中桩侧负摩阻力所产生的作用于桩体上的下拽力,可能引起桩体破坏、桩基不均匀沉降等诸多工程灾害。为此,工程师们建立了许多单桩负摩阻力计算公式,但是由于这些公式各自的适用性和局限性,计算结果差别较大。首先介绍了目前国内外用于计算单桩负摩阻力及确定中性点位置的几种常用方法:极限分析法、荷载传递法、弹性或弹塑性理论法、剪切位移法和数值分析法;再结合具体工程实例,对以上几种方法进行比较,指出各自的适用条件、优缺点等,为工程设计提供参考。