Influence of GSTM1 and GSTT1 genotypes and confounding factors on the frequency of sister chromatid exchange and micronucleus among road construction workers

In the present study, we have investigated the influence of polymorphism of GSTM1 and GSTT1 genes and confounding factors such as age, sex, exposure duration and consumption habits on cytogenetic biomarkers. Frequency of sister chromatid exchanges (SCEs), high frequency cell (HFC) and cytokinesis blocked micronuclei (CBMN) were evaluated in peripheral blood lymphocytes of 115 occupationally exposed road construction workers and 105 unexposed individuals. The distribution of null and positive genotypes of glutathione-S transferase gene was evaluated by multiplex PCR among control and exposed subjects. An increased frequency of CBMN (7.03 ± 2.08); SCE (6.95 ± 1.76) and HFC (6.28 ± 1.69) were found in exposed subjects when compared to referent (CBMN - 3.35 ± 1.10; SCE - 4.13 ± 1.30 and HFC - 3.98 ± 1.56). These results were found statistically significant at p < 0.05. When the effect of confounding factors on the frequency of studied biomarkers was evaluated, a strong positive interaction was found. The individuals having GSTM1 and GSTT1 null genotypes had higher frequency of CBMN, SCE and HFC. The association between GSTM1 and GSTT1 genotypes and studied biomarkers was found statistically significant at p < 0.05. Our findings suggest that individuals having null type of GST are more susceptible to cytogenetic damage by occupational exposure regardless of confounding factors. There is a significant effect of polymorphism of these genes on cytogenetic biomarkers which are considered as early effects of genotoxic carcinogens.     

Assessment of organochlorine pesticide residues in Atlantic Rain Forest fragments, Rio de Janeiro, Brazil

A superficial water quality survey in a watershed of the Paraíba do Sul River, the main water supply for the most populated cities of southeastern Brazil, was held in order to assess the impact of the expansion of agricultural activity in the near border of the Atlantic Rain Forest. The aim of this study was to investigate the presence of priority organochlorine pollutants in soils and superficial waters of Atlantic rainforest fragments in Teresópolis, Rio de Janeiro State. Soil sample preparations were compared by using ultrasound, microwave assisted extraction and Soxhlet extraction. Recoveries of matrix spiked samples ranged from 70 to 130%. Analysis of a certified soil material showed recoveries ranging from 71 to 234%. Although low concentrations of organochlorine residues were found in water and soil samples, this area is of environmental importance and concern, thus demanding a monitoring program of its compartments.     

Dynamics, deterministic nature and correlations of outdoor (222)Rn and (220)Rn progeny concentrations measured at Bacău, Romania

The long-term variation, nature and correlations of outdoor ²²²Rn and ²²⁰Rn progeny concentrations measured during the period 1994-2009 were investigated. The time series of data were obtained within the framework of the monitoring program performed by the Environmental Radioactivity Monitoring Station (ERMS) Bac?u, a component part of the National Environmental Radioactivity Survey Network (NERSN), coordinated by National Environmental Protection Agency (NEPA). The measuring method is based on the total beta measurements of atmospheric aerosol filters, using a low background total beta counter and (⁹⁰Sr/Y) reference standard. Analysis of the time series of progeny concentrations in the low atmosphere makes evident different patterns of variation of these concentrations: diurnal, seasonal and annual. A possible relationship of progeny concentration increase with global warming is emphasized. In order to find the dominant frequency of the physical processes determining progeny concentration variability the power spectrum has been used. The deterministic nature of the time series of concentrations has been studied making use of the autocorrelation function and stationarity of the original data and of their phase randomized time series. Also, the correlations with meteorological parameters have been investigated using Pearson’s correlation coefficient with corresponding level of significance.     

化工事故应急救援仿真演练系统的实施探讨

阐述了化工事故应急救援仿真的必要性及其国内外研究进展;提出整个系统的框架并设计系统开发过程的模型;分析了基于高层体系结构(HIA)的仿真系统的开发要点,给出参考开发工具,从而为整个系统开发提供思路.     

Critical review of Integrated Water Resources Management: Moving beyond polarised discourse

Integrated Water Resource Management (IWRM) emerged as a popular concept in the water sector in the 20th century. From a highly techno-centric approach in the past, it has taken a new turn embracing Habermasian communicative rationality as a place-based nexus for multiple actors to consensually and communicatively integrate decisions in a hydrological unit. The 'how to integrate' approach had remarkable appeal worldwide in promoting authentic participation of all stakeholders. However, critics argue that the domain of water resource management is a political process of contestation and negotiation; the emphasis is on complexities, contextuality, power dynamics and the importance of analysing real world situations. They demonstrate 'how integration cannot be achieved' given the power dynamics in social interactions. These apparently contradictory discourses draw on different theoretical paradigms and polarise the discourse on IWRM, without offering constructive alternatives. To this end, this paper offers an option to complement this polarised discourse by examining 'how integration actually does take place' in a strategic context thereby facilitating consensual decisions to integrate water management for a sustainable future.     

环境生物样品预处理中的微波溶样技术

微波溶样是近年产生的一种崭新的有前途的样品预处理技术，本文评述这一技术在环境、生物样品消解方面的近期应用。     

控制排气放空噪声的消声器之研究与应用

排气放空噪声是工业上常遇到的噪声源。本文介绍了根据喷注噪声发射理论研制成的小孔喷注与节流降压相复合的新型消声器，适用于高压气源排放，取得了较好的消声效果。鉴于喷注发射噪声的强度取决于喷注的驻压与喷口直径等参量，对节流降压层的设计与控制小孔喷注层的驻压大小，提出了新的见解，可供设计研究喷注消声器参考使用。     

‘The good district’: Newbury as a seed‐bed for success

This study analyses the behaviour of high technology and new firms in the Newbury District of Berkshire in terms of employment, location, genealogy, and local economic impact. It finds that encouraged by good communications networks and a ‘resident electronics establishment’, the direct, as opposed to the indirect, employment consequences are generally encouraging, but not widely replicable. Moreover, the general picture of employment growth masks important differences in labour demand across occupations, particularly with respect to ‘traditional male’ skilled manual workers.     

南京理工大学高压实验室及其研制高压水射流切割机

南京理工大学高压实验室自８０年代初建立以来，在高压容器及武器发射管的自紧理论和工程应用、高压零部件研制、高压传感器和信号放大显示系统、高压介质等方面做了大量的工作。９３年以来，进行了水射流切割机的研制工作，解决了超高压缸体的动态密封、高压缸体的自增强、无触点式换向传感器、内衬不锈钢组合型高压容器等诸多问题，试制成功了水射流切割机样机。     

CENTRAL NEBRASKA RIVER BASINS,NEBRASKA1

ABSTRACT: The Central Nebraska Basins (NAWQA) study unit includes the Platte River and two major tributaries, the Loup and Elkhorn Rivers. Platte River flows are variable in the western part of the study unit because of diversions, but the Loup and Elkhorn Rivers originate in an area of dune sand covered by grassland that generates consistent base flows. More frequent runoff in the eastern part of the study unit also sustains stream flow. Ground water in the study unit has no regional confining units and the system is a water table aquifer throughout. Macroinvertebrate and fish taxa at biological sampling sites in the state were related to stream flow. One of the four wetland complexes identified in the study unit includes habitat for threatened and endangered bird species. The study unit is an agricultural area that includes row crops, both irrigated and nonirrigated in the eastern and southern parts, and rangeland in the Sand Hills of the western part. A water quality assessment will be based on the differences in environmental setting in each of four subunits within the study unit.]