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31.
IntroductionCadmium(Cd)isanon essentialtracemetalthathasadverseeffectsonplants,animalsandhumans.EnvironmentalcontaminationwithCdduetoanthropogenicactivities,suchasmining,industry,agricultureandwastedisposalhasbeenincreasingsincethebeginningofthe 2 0thcentury (Alloway,1995) .ResearchoncontrollingCdpollutionassociatedwithassessingandmanagingacuteinjurytohumanhealththroughoccupationalexposureanddisposalofCdfromindustrialpointsourcestolocalpopulationsthroughseveralpathwayshasmadeconsiderableadva… 相似文献
32.
Soil factors associated with zinc deficiency in crops and humans 总被引:10,自引:0,他引:10
B. J. Alloway 《Environmental geochemistry and health》2009,31(5):537-548
Zinc deficiency is the most ubiquitous micronutrient deficiency problem in world crops. Zinc is essential for both plants
and animals because it is a structural constituent and regulatory co-factor in enzymes and proteins involved in many biochemical
pathways. Millions of hectares of cropland are affected by Zn deficiency and approximately one-third of the human population
suffers from an inadequate intake of Zn. The main soil factors affecting the availability of Zn to plants are low total Zn
contents, high pH, high calcite and organic matter contents and high concentrations of Na, Ca, Mg, bicarbonate and phosphate
in the soil solution or in labile forms. Maize is the most susceptible cereal crop, but wheat grown on calcareous soils and
lowland rice on flooded soils are also highly prone to Zn deficiency. Zinc fertilizers are used in the prevention of Zn deficiency
and in the biofortification of cereal grains. 相似文献
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34.
双峰驼骨质疏松症的流行特点及其与生物地球化学因子之间的关系 总被引:1,自引:0,他引:1
研究了双峰驼骨质疏松症的流行特点及与生物地球化学因子之间的关系,结果表明,在从腾格里沙漠西南端开始向巴丹吉林沙漠的西北方向延伸形成大约长600km,宽160km的狭长发病区域内,该病发病率为28.8%,致死率达60%,该区土壤、牧草中Cu、P含量极显著低于正常值(p<0.01),牧草中m(Ca):m(P)为50:1;病驼全血和被毛P含量亦低于健康驼(P<0.01).因此认为该病主要是由双峰驼食物链中P缺乏所致的一种骨营养不良症. 相似文献
35.
为研究潜在富硒土壤硒生物有效性,采集安徽庐江潜在富硒地区64组水稻及对应根系土壤样品,分析土壤理化性质、土壤养分、全硒、不同形态硒及大米硒含量,采用线性回归法探究土壤硒生物有效性的影响因素.结果表明,大米硒含量(记作Serice,下同)为0.037~0.120 mg/kg,土壤全硒含量(记作Setot,下同)为0.260~1.177 mg/kg,土壤硒以腐殖酸态硒(15.5%~44.7%)、强有机态硒(12.5%~53.3%)和残渣态硒(8.1%~68.5%)为主.土壤有效硫、有效磷通过提高强有机态、腐殖酸态和浸提性硒含量并促进水稻籽实(大米)对硒的吸收,而土壤阳离子交换量(cation exchange capacity,CEC)、速效钾、全铁和全锰通过降低水稻生物可利用态硒含量(包括水溶态、腐殖酸态、强有机态和浸提性硒)抑制水稻籽实(大米)对硒的吸收.Setot与Serice显著正相关(R=0.616,P < 0.01),非残渣态硒含量与有机质含量之比(记作NRE-Se/OM)与Serice相关性最强(R=0.774,P < 0.01).土壤NRE-Se/OM、有效硫、有效铁、全锰构建的多元逐步线性对数回归模型可解释水稻籽实(大米)吸收硒的76.0%的方差.因此引入变量NRE-Se/OM,并结合土壤有效硫、有效铁和全锰能有效评价和预测研究区土壤硒生物有效性. 相似文献
36.
Leukocyte adhesion deficiency (LAD) is a rare autosomal recessive disorder which leads to recurrent severe infections due to impaired leukocyte functions. The disorder is caused by an absence or deficiency of leukocyte cell adhesion molecules (LeuCAMs) on the leukocyte membranes. The diagnosis is established with monoclonal antibodies against the LeuCAMs. We have carried out a prenatal diagnostic procedure by means of cordocentesis in a mother who was 20 weeks pregnant and had previously given birth to a child with LAD. This previous child had the severe form of LAD with undetectable mRNA for the β chain, the common subunit of the LeuCAMs. We found that the fetal granulocytes expressed the LeuCAMs normally. At birth, the baby was physically normal and showed no signs of impaired leukocyte functions. 相似文献
37.
Hayato Kihara Aryan L. Fluharty Katherine K. Tsay Ronald P. Bachman John D. Stephens Won G. Ng 《黑龙江环境通报》1983,3(1):29-34
Prenatal diagnosis was performed on a pregnancy at risk for metachromatic leukodystrophy (MLD) in a family with the pseudo arylsulphatase A deficiency trait. Extracts of cultured amniotic fluid cells were deficient in arylsulphatase A indicating that the fetus was either affected with MLD or had the benign pseudodeficiency trait. In the cerebroside sulphate loading test, the at risk cells hydrolysed sulphatide like control cultured amniotic fluid cells implying that the fetus had pseudodeficiency. The pregnancy was carried to term and a male child was delivered. Placenta, urine and fibroblasts had very low activities of arysulphatase A. However, no sulphatide could be detected in urine and growing fibroblasts responded normally in the cerebroside sulphate loading test, suggesting pseudodeficiency. At 29 months, the infant is healthy and shows no stigmata of MLD. The prediction based on the results of the cerebroside sulphate loading test on cultured amniotic fluid cells appeared to be borne out. 相似文献
38.
Dr. H. Grosse-Wilde E. Valentine-Thon U. Vögeler E. Passarge F. Lorenzen W. G. Sippell F. Bidlingmaier D. Knorr 《黑龙江环境通报》1988,8(2):131-143
In 18 families at risk for the HLA-linked, 21-hydroxylase deficient form of autosomal recessive congenital adrenal hyperplasia (CAH), prenatal diagnosis (PD) was performed using two methods: (1) HLA-A,B,C typing and in the latter 11 cases also DR typing of cultured amniotic fluid cells (AFC) using the standard microcytotoxicity assay, and (2) measurement of second trimester amniotic fluid 17-hydroxyprogesterone (17-OHP) concentration using gel chromatography and radioimmunoassay. The accuracy of the prenatal predictions was confirmed by postnatal HLA typing of umbilical cord blood lymphocytes and by clinical evaluation. In 16/18 families, both HLA typing of AFC and 17-OHP measurements proved informative for PD. The predictions of both methods were concordant in 14/16 families (88 per cent). In ten of these families, a normal fetus was predicted, and in four, an affected fetus; all pregnancies were carried to term and all predictions were confirmed postnatally. In 2/16 cases (12 per cent), however, the predictions were discordant: the prenatal HLA typing indicated an affected fetus, whereas the 17-OHP values predicted a normal fetus. Both pregnancies were continued and two healthy boys were delivered. The discordance proved to be due to a ‘missed’ HLA antigen in one case and to serologically cross-reactive HLA antigens in the second. Finally, in 2/18 cases, prenatal assessment of fetal genotype had to rely on HLA typing alone as 17-OHP measurement was not performed in one family and in the second family the 17-OHP values obtained were not informative due to inadvertent continuation of hormone therapy to the date of amniocentesis. In both cases, the HLA typing data accurately predicted a normal fetus. In conclusion, a combination of HLA typing of cultured AFC and 17-OHP measurements of amniotic fluid permits accurate prenatal diagnosis of CAH in most cases (88 per cent). In addition, the supplementary use of HLA-DR typing of AFC as presented here for the first time proved helpful in families with HLA-A.B homozygosity due to parental sharing of antigens and can be informative for identifying HLA-B/21-OH recombinant haplotypes. 相似文献
39.
40.
低硒环境中人群对不同形态硒的保留量及其效应的研究 总被引:3,自引:1,他引:3
研究了低硒生态环境中有明显早期大骨节病病变的人群服用富硒酵母,亚硒酸钠和肌肉注射硒代二乙酸后体内硒保留量的动态变化。分析了治疗效应与摄入三种形态的硒后硒在体内保留量的关系,并与对照组作了比较。讨论了不同形态硒的生物活性。研究结果是三种形态的硒对早期大骨节病病变均有非常显著的疗效,再一次证明低硒生态环境是大骨节病流行的基础。 相似文献