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Forty-two open neural tube defects (NTDs) were identified in our series of 7440 amniocenteses tested between 11 and 15 weeks of gestation. Using a cut-off of ≥2.0 MOM, the detection rate for open NTDs was 95 per cent; 100 per cent each for anencephaly and spina bifida; and 78 per cent for encephalocele. Two encephaloceles had AFP levels less than 2.0 MOM and negative AChEs. Thirty-four (81 per cent) of these NTDs were tested between 13 and 15 weeks and 8 (19 per cent) before 13 weeks. There were 0.6 per cent false positives by AFP (excluding serious abnormalities and fetal death) and 0.1 per cent after AChE. The likelihood of an open NTD after an elevated AFP (≥2.0 MOM) was 24 and 77 per cent for any serious abnormality. These results, when combined with an earlier study, indicate that amniotic fluid AFP appears to be as sensitive a test for open NTDs between 13 and 15 weeks as between 16 and 20 weeks. Additional experience is necessary to determine this before 13 weeks. 相似文献
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Cynthia J. Sims MD Don T. Fujito Dennis R. Burholt Josef Dadok Harlan R. Giles D. Allan Wilkinson 《黑龙江环境通报》1993,13(6):473-480
We have investigated the ability of high-resolution proton NMR spectroscopy to provide a biochemical constituent screening of human amniotic fluid (AF). Proton NMR spectra were obtained at 300 MHz on AF from patients undergoing amniocentesis in the mid-trimester. Only AF from normal pregnancies (normal fetal karyotype, normal a-fetoprotein levels, normal birth outcome) was used in this study. The AF supernatant was lyophilized and resuspended in deuterated water containing 0.1 mm phosphate buffer and 6.02 mm disodium maleate. Identification of low molecular weight compounds was confirmed by two-dimensional NMR spectra (primarily correlated spectroscopy, or COSY) and standard addition techniques. A broad profile of compounds were ‘NMR visible’ in a single proton spectrum, including creatinine, glucose, organic acids (acetate, citrate, and lactate) and several amino acids (alanine, histidine, leucine, phenylalanine, tyrosine and valine). The proton spectrum was unaffected by prior freezing/thawing of AF samples. We were able to quantify compounds by comparison with an added concentration standard (maleate) at concentrations as low as 30 μm. Good agreement with literature values based on other analytical techniques was obtained. 相似文献
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排污许可证交易的理论与实践 总被引:17,自引:0,他引:17
排污许可证交易是市场经济体制下控制污染的有效措施。本文对排污许可证交易的基本理论、排污许可证交易的优点、排污许可证交易的可行性、排污许可证的交易方式、排污许可证的交易程序、初始排污权分配、交易资金的使用等问题进行了探讨。 相似文献
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大气污染物浓度分布等值曲线的绘制是大气环境影响预测的一项重要工作.采用优化的黑白域矩形网格序列法,结合VB.NET环境下Metafile对象提供的矢量图形绘制新技术,可在一次数据扫描过程中同时实现黑白域划分、黑域边界提取、等值点拟合计算及序列化、等值线绘制等操作,计算量小、效率高、代码量少,可绘制任意浓度等值线,且等值线不相切. 相似文献
19.
Liu Zhenyu Yang Fenglin Quan Xie Zhang Xiaohong 《Frontiers of Environmental Science & Engineering in China》2007,1(2):166-171
A QWASI model dependent on temperature is parameterized to describe the long-term fate of persistent organic pollutants (POPs)
in the Liao River. The model parameters, namely fugacity capacity, degradation rate, and transfer coefficient, are profoundly
affected by temperature. This model is used to simulate the fate of γ-hexachlorocyclohexane (γ-HCH) in the lower reaches of the Liao River from 1998 to 2008. Modeling results show that γ-HCH fugacity capacities in air, water, and sediment increase as temperature decreases, and the transfer and transformation
rate coefficients increase as temperature increases. The variations of transfer and transformation parameter D values depend on fugacity capacities, and transfer and transformation coefficients simultaneously. The performance of the
model is evaluated by comparing the predicted and observed concentrations in the water and sediment of the Liao River. The
predicted values agree well with the observed value in the order of magnitude, in most cases within the factor of 3. It is
believed that the model is appropriate for simulating the long term fate of POPs in the Liao River.
Translated from Environmental Science, 2006, 27(1): 121–125 [译自: 环境科学] 相似文献
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上海市大气中NMHC,NOx,O3和SO2变化规律 总被引:7,自引:0,他引:7
通过对上海市大气中光化学主要污染物如NMHC、NOx、O3及SO2等的日变化监测,发现NOx、O3的日浓度变化与气象条件密切相关,高浓度O3多出现在晴朗少云,气温较高的大气条件下同步监测发现,O3与NOx呈负相关,相关系数r=-0.785;dmj SO2gn NMHCe tve vb r ghd sh ud ,sh ud txi ovt r= 相似文献