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101.
内分泌干扰物通过干扰内分泌系统导致多种疾病,如生殖疾病、肥胖症甚至癌症。然而,面对环境中大量潜在的内分泌干扰物,传统的体外、体内评估方法由于成本高、耗时长等问题,难以实现内分泌干扰物的高通量筛查。计算毒理学逐渐发展成为被美国环保局(Environmental Protection Agency,EPA)、经济合作与发展组织(Organization for Economic Co-operation and Development,OECD)等机构所推荐的内分泌干扰物筛选与预测方法。本文综述了计算毒理学在内分泌干扰物筛选上的进展,主要包括分子对接和分子动力学模拟的应用,并对有害结局路径(adverse outcome pathway,AOP)的方法进行介绍和展望。 相似文献
102.
George E. Halkos Epameinondas A. Paizanos 《Journal of Environmental Planning and Management》2017,60(1):135-157
This paper explores the relationship between government spending and environmental quality using panel data for 94 countries for the period 1970–2008. We identify and estimate three distinct channels that comprise the total direct effect of government expenditure on air pollution, namely a marginal effect, an effect conditional on economic growth and an effect conditional on institutional quality. Since adjustment rate of emissions to their equilibrium level is slow due to technological and institutional reasons, we explicitly take into account dynamics by applying appropriate econometric methods. The results demonstrate that there is a significant alleviating direct effect of government expenditure on SO2 and NOx emissions, which increases with the level of economic growth and democracy. However, there is no evidence of a significant effect on pollutants with more global impact on the environment and human health, like N2O and CO2, implying that the adoption of international environmental treaties is required in this case. 相似文献
103.
Mingxuan Mao Li Zhang Qichang Duan O.J.K Oghorada Pan Duan Bei Hu 《International Journal of Green Energy》2017,14(8):694-702
The power-voltage (P-V) characteristic curves of a PV array are nonlinear and have multiple peaks under partially shaded conditions (PSCs). This paper proposes a novel maximum power point tracking (MPPT) method for a PV system with reduced steady-state oscillation based on a two-stage particle swarm optimization (PSO) algorithm. The grouping method of the shuffled frog leaping algorithm (SFLA) is incorporated in the basic PSO algorithm (PSO-SFLA), ensuring fast and accurate searching of the global extremum. An adaptive speed factor is also introduced into the improved PSO to further enhance its convergence speed. Test results show that the proposed method converges in less than half the time taken by the conventional PSO method, and the power is improved by 33% under the worst PSCs, which confirms the superiority of the proposed method over the standard PSO algorithm in terms of tracking speed and steady-state oscillations under different PSCs. 相似文献
104.
Global climate change is one of the major environmental issues faced by humans.Existing evidence indicates that the anthropogenic push for a rise in the atmospheric concentration of greenhouse gases(GHGs)(particularly CO_2)has been a primary cause for global warming.Aside from economic and teclinological factors,demographic dynamics(including human consumption in a broad demographic sense)has been a major driver for CO_2 emissions.In this paper,we performed both nonlinear regression analysis(based on the STIRPAT model)and gray correlation degree analysis(based on gray system theory)on the impact of demographic dynamics on CO_2 emissions.Our results reveal that CO_2 emissions are positively correlated with population size and GDP per capita and negatively correlated with energy intensity.We also show that gray correlation degree with CO_2 emissions for five variables(i.e.,household consumption,urbanization rate,household size,population aging rate,population size)varies substantially:household consumptionurbanization ratehousehold sizepopulation aging ratepopulation size,with household consumption being the highest,and population size the lowest.To mitigate the impact of demographic dynamics on CO_2 emissions,it is of vital significance to nurture people's awareness of sustainable consumption and to adhere to current population control policies. 相似文献
105.
北京市水资源开发利用已经超过了水资源承载能力范围,由此引发的水资源短缺问题日益严重.对污水的综合利用进行研究可以达到持续利用水资源的目的,解决水资源短缺问题.以北京市2005-2012年污水排放量资料为基础,运用灰色系统模型,对工业、生活污水排放量及总污水排放量进行了预测,分析北京市污水排放量走势及存在的问题,提出未来北京市污水综合利用的对策措施. 相似文献
106.
The paper tests the material Kuznets Curve (MKC) hypothesis with regard to aluminium consumption for 20 high-income countries over the period 1970 to 2009. The test is based on the suggestion of Narayan and Narayan (2010). Various unit root and cointegration tests are applied. The aluminium and GDP series are found to be integrated of order one and cointegrated. Additionally, the Blundell–Bond system generalized methods-of-moments (GMM) is employed to conduct a panel causality test in a vector error-correction mechanism (VECM) setting. Unidirectional causality running from real per capita GDP to the aluminium intensity is uncovered in both the short-run and long-run. While controlling for structural shocks, the MKC hypothesis is found to hold at individual levels for Austria, Canada, Denmark, Finland, Greece, Italy, Japan, and United Kingdom as well as for the whole panel. A 1% increase in GDP generates an increase of 0.87% in metal intensity in the short-run and a fall of 0.82% in the long-run for the panel. 相似文献
107.
108.
Jae H. Ryu Bryce Contor Gary Johnson Richard Allen John Tracy 《Journal of the American Water Resources Association》2012,48(6):1204-1220
Abstract: Water supply uncertainty continues to threaten the reliability of regional water resources in the western United States. Climate variability and water dispute potentials induce water managers to develop proactive adaptive management strategies to mitigate future hydroclimate impacts. The Eastern Snake Plain Aquifer in the state of Idaho is also facing these challenges in the sense that population growth and economic development strongly depend on reliable water resources from underground storage. Drought and subsequent water conflict often drive scientific research and political agendas because water resources availability and aquifer management for a sustainable rural economy are of great interest. In this study, a system dynamics approach is applied to address dynamically complex problems with management of the aquifer and associated surface‐water and groundwater interactions. Recharge and discharge dynamics within the aquifer system are coded in an environmental modeling framework to identify long‐term behavior of aquifer responses to uncertain future hydrological variability. The research shows that the system dynamics approach is a promising modeling tool to develop sustainable water resources planning and management in a collaborative decision‐making framework and also to provide useful insights and alternative opportunities for operational management, policy support, and participatory strategic planning to mitigate future hydroclimate impacts in human dimensions. 相似文献
109.
110.
This study projected responses of forest net primary productivity (NPP) to three climate change scenarios at a resolution
of 5 km × 5 km across the state of Louisiana, USA. In addition, we assessed uncertainties associated with the NPP projection
at the grid and state levels. Climate data of the scenarios were derived from Community Climate System Model outputs. Changes
in annual NPP between 2000 and 2050 were projected with the forest ecosystem model PnET-II. Results showed that forest productivity
would increase under climate change scenarios A1B and A2, but with scenario B1, it would peak during 2011–2020 and then decline.
The projected average NPP under B1 over the years from 2000 to 2050 was significantly different from those under A1B and A2.
Forest NPP appeared to be primarily a function of temperature, not precipitation. Uncertainties of the NPP projection were
due to large spatial resolution of the climate variables. Overall, this study suggested that in order to project effects of
climate change on forest ecosystem at regional level, modeling uncertainties could be reduced by increasing the spatial resolution
of the climate projections. 相似文献