The association between alpha-fetoprotein and βhcg levels prior to and following chorionic villus sampling in cases that spontaneously miscarried

Maternal serum alpha-fetoprotein (AFP) and beta-human chorionic gonadotropin (βhCG) measurements taken prior to chorionic villus sampling (CVS) in 21 patients who subsequently miscarried were compared with measurements in a control group of 113 patients with uneventful pregnancies. Patients with AFP levels of 10 iu/ml or more prior to the CVS had a 4·3 times greater risk of miscarriage (95 per cent confidence interval 1·3–13·6). AFP levels obtained 1 week after the CVS in the 13 patients with late miscarriages were higher than in the control group (P = 0·06). Patients miscarrying had a greater rise in AFP (P = 0·06) and a greater fall in βhCG levels (P = 0·04) following the CVS procedure, compared with the control subjects. Each 10-unit change in the difference between AFP or βhCG levels prior to and 1 week following the CVS was associated with a significantly increased risk for late miscarriage. Elevated maternal serum AFP levels early in pregnancy and changes in AFP and βhCG levels following CVS may predict an increased risk for subsequent miscarriage.     

Use of the chemical cleavage of mismatch method for prenatal deficiency diagnosis of alpha-1-antitrypsin

The most common mutation in alpha-1-antitrypsin deficiency, conversion of a G to an A at base 9989 (PI-Z), was detected with the chemical cleavage of mismatch method, demonstrating the power of the method for prenatal diagnosis. Exon V of the gene was amplified using the polymerase chain reaction and heteroduplexes were formed to test for the presence of the mutation. The predicted C mismatch was readily detectable with hydroxylamine, and by making the probe from the chorionic villus sample it was possible to determine that the fetus was heterozygous, not homozygous, for the mutation.     

假单胞菌的氯儿茶酚1,2-双加氧酶基因的克隆和表达

 从土壤中分离得到1株降解2,4-二氯酚(2,4-DCP)能力较强的细菌菌株GT241-1,克隆了该菌株的3,5-二氯儿茶酚1,2-双加氧酶基因(dcpB),采用的克隆策略为:用Southern杂交对dcpB进行定位后,构建重组质粒,再用斑点杂交从重组质粒中筛选目的转化子.经序列测定得知dcpB亚克隆片段全长4303bp,其中dcpB基因编码区765bp.核苷酸和推测的氨基酸序列分析表明,dcpB与已在GenBank登记的相关基因有一定的差异.dcpB基因能够在大肠杆菌转化子中成功地表达有生物活性的酶.     

Effects of bifenthrin on Daphnia magna during chronic toxicity test and the recovery test

IntroductionWiththedevelopmentandapplicationofnewpesticide ,insecticidehasgreatlyreducedtheharmofpesttocrops .Bifenthrinisaneffectivepyrethroidinsecticideandacaricideagainstawiderangeofinsectpests ,anditisverypoisonoustomammal,aquatic .Thisinsecticideiswi…     

103-J合成气压缩机危险性分析

结合合成气压缩机既往发生的事故,根据辽宁省劳动局制定的工厂危险程度分级要求,对103－J合成气压缩机进行了危险性分析。     

兰州市交通要道颗粒物污染状况及其致突变活性的研究

采用现场监测，色－质联用分析以及小鼠骨髓微核试验方法，评价了兰州市交通要道颗粒物的污染状况，分析了颗粒提取物（PE）的有机组成及致突变活性。结果表明，兰州市总悬浮颗粒物（TSP）污染严重。颗粒提取物中含有近100种有机化合物，其中包括致癌性多环芳烃。微核试验显示PE具有致突变活性，对人群健康的影响不容忽视。     

SBR法运行控制工艺研究进展

SBR法是一种具有独特的优点的废水生物处理工艺，但至今还没有一套公认的运行控制工艺，本文从SBR法的启动，充水时间及反应时间的确定，模糊控制，目标控制操作等几方面对SBR工艺的运行控制做了评述，并对其今后的研究方向做了展望。     

Direct hydride derivatization of methyl- and ethylmercury chlorides in aqueous solution with KBH4

A convenient hydride derivatization procedure of methyl-and ethylmercury chlorides to volatile hydrides was reported. In sealed vials methylmercury and ethylmercury compounds in acidic aqueous solutions were converted into their volatile forms by the reaction with potassium tetrahydroborate(KBH4) and elvolved to the headspace of the vials. The gaseous analytes in the headspace were extracted and concentrated by solid phase microextraction(SPME) and injected into gas chromatography (GC) for separation and identified by mass selective detector(MS).     

焚烧废气处理试验研究

介绍了有毒有害焚烧废气处理的原理及工艺流程,分析了焚烧废气中粉尘、HCl和NOx去除的原理,根据焚烧废气处理的试验结果,探讨了影响处理效果的因素.试验表明,在试验条件下,焚烧废气中的粉尘、NOx、HCl在吸收塔均达到较高的去除效率,其中粉尘的去除效率92%;NOx的去除效率平均58%,高的可达80%;HCl的去除效率平均达87%.随着液气比增大,其各种污染物的去除效率有所增加.     

煤炭燃烧排砷水平与控制技术研究

煤炭是我国目前的主要一次能源之一,燃煤中的重金属污染愈来愈受到重视,如何控制煤炭中砷向环境中扩散,减轻环境污染是近年来重要的研究课题.通过开展对铁法煤业集团内部高砷煤和低砷煤的动力配煤燃烧试验,分析动力配煤燃烧过程中的砷迁移水平,研究铁法煤业集团内部动力配煤燃烧过程中的砷迁移规律和动力配煤降砷的可行性,并为开展最佳动力配煤操作数据提供理论依据,为高砷煤燃烧控制砷的排放寻找治理途径,提高煤炭资源的最大利用效率.