职业安全健康工作的核心是对人力资源的保护

随着经济和社会的发展,职业安全健康工作越来越受到党和国家领导人的重视。切实做好职业安全健康研究与管理工作是落实科学发展观的基本标志之一,而职业安全健康工作的核心是对人力资源的保护。因此我们要充分认识到加强职业安全健康工作的重要性、必要性和紧迫性,让广大劳动者实现"体面劳动"。一要加强职业安全健康监管,二要借鉴经验完善体制,三要加大相关职业安全健康科学技术研究。只有全面提升人力资源保护,贯彻落实"科技兴安"战略,加强人力资源管理,才能确保劳动者在劳动生产过程中的安全与健康。     

民航空管安全文化建设探析

根据民航空管安全发展的客观规律,在综合考虑践行空管持续安全理念、减少空管人为差错、建设空管安全管理体系的基础上,提出要实现我国民航的持续安全,就要构建并不断完善空管安全文化建设的有效手段和途径。对空管安全文化建设的途径展开了深入探索,并提出了相关建议和措施,包括开展技能竞赛等文化娱乐活动、建立管制员心理培训与辅导机制、提升管制员新技术适应能力等。空管安全文化的建设是空管发展的坚强后盾,有效手段和措施建设的推进将成为航空运行安全的有力保障。     

基于CREAM方法的人因失效概率预测模型研究

认知可靠性与差错分析方法(CREAM)是第二代人因可靠性分析方法中的代表方法之一,通过对任务环境进行分析从而直接确定人为差错发生概率。本文分析了该方法及其后续研究在人因可靠度评估时存在的主要问题,并以CREAM方法为基础建立新的人因失效概率预测模型。模型首先要求有针对性的对具体任务环境确定通用性能影响因子(CPC)权重,然后通过对CPC进行打分对任务环境进行量化,通过加权求和的方式分别计算出CPC的改进总分值G和降低总分值J,最后运用新建的预测模型计算出人因失效概率。新模型提出了三点改进:第一将任务环境设定为连续的空间;第二提出了不同的工作环境(任务环境)应该有其对应的CPC因子权重;第三考虑正影响CPC因子和负影响CPC因子的双重影响,建立双变量预测模型,预测结果更加合理。     

融合控制策略在污水处理曝气过程中的应用

针对污水处理过程的复杂性,提出了一种融合控制策略。探讨了基于融合的工程控制策略和控制算法。仿真实验结果表明:该工程控制算法的控制精度高,鲁棒性强,对污水处理过程的控制是可行和有效的。     

生物样品中含PBDEs在内的复合污染组分的抗雌激素效应

为初步探讨电子废物拆解导致的多溴二苯醚(PBDEs)及其类似物构成的复合污染的潜在生态/健康风险,从电子废物拆解区的三黄鸡血液和肝脏样品中提取了包含PBDEs在内的复合污染组分,分别体外暴露乳腺癌MCF-7细胞和MDA-MB-231细胞6d,检测细胞增殖和雌激素靶基因pS2的mRNA表达.结果表明,包含多种PBDEs在内的复合污染组分在不产生细胞毒性的前提下,可显著抑制MCF-7细胞增殖和雌激素靶基因pS2的mRNA表达,表现出抗雌激素活性.此结果提示由电子废物拆解造成的复合污染对生物体和人体可能存在潜在的生态/健康风险.     

人为干扰对江油地区马尾松人工林群落结构和物种多样性的影响

物种多样性是群落功能复杂性和稳定性的重要量度指标,人为干扰对森林群落的影响可以通过群落结构和物种多样性的变化而直接显现,不同干扰强度下的森林群落结构和物种多样性特征不同。采用典型样地法,对比研究两种人为干扰强度（干扰强和弱）对江油地区的马尾松（Pinus massoniana）人工林群落的物种组成、群落结构和物种多样性的影响,采用物种丰富度指数D值、Shannon-wienner指数H值、Simpson优势度指数H′值和均匀度指数Jsw值来综合衡量群落的物种多样性水平。结果表明,（1）在总面积3200 m2的8个样地中记录到124个物种,隶属于105属56科,干扰强的群落各层次物种数均低于干扰弱的群落。（2）不同强度人为干扰下马尾松人工林的群落结构不同,干扰弱的群落径级结构呈近正态分布,在径级Ⅵ（7 cm≤d〈9 cm）处出现数量的峰值26株,群落结构较稳定;干扰强的群落径级结构不呈正态分布,在径级Ⅶ（13 cm≤d〈15 cm）处出现峰值43株。干扰弱和干扰强的群落高度级结构与其径级结构具有相似性,干扰弱的群落的个体主要集中在低中高度级（3≤H〈17）;干扰强的群落的个体数在各高度级分布不均匀,主要分布在中高高度级（H≥13）;干扰强的群落的个体数在各径级和高度级分布相对不均匀,群落结构趋于不稳定。（3）人为干扰对马尾松人工林群落造成负面影响,随着人为干扰强度的增加,物种丰富度指数D值、Shannon-wiener多样性指数H值、均匀度多样性指数Jsw值降低,Simpson优势度指数H′值增大,物种多样性呈下降趋势。     

Fate of proteins of waste activated sludge during thermal alkali pretreatment in terms of sludge protein recovery

Maillard reaction between reducing sugars and amides happened during pretreatment. Over 90 min of TAH at the optimal condition, 67.59% sludge proteins was solubilized. 15.84% soluble proteins broke down to materials with small molecular weight. Proteins are the major organic component s of waste activated sludge (WAS); the recovery of sludge proteins is economically valuable. To efficiently recover sludge proteins, WAS should undergo hydrolysis pretreatment to fully release proteins from sludge flocs and microbial cells into aqueous phase. One of the most widely used chemical methods for that is thermal alkali hydrolysis (TAH). Here, the soluble protein concentration achieved the highest level over 90 min of TAH pretreatment at 80°C; the sludge floc disintegration and microbial cell destruction were maximized according to the content profiles of bound extracellular polymeric substance (EPS) and ribonucleic acid (RNA) of sludge. Both less proteins broken down to materials with small molecular weight and less melanoidin generated were responsible. TAH pretreatment at 80°C for 90 min resulted in the solubilization of 67.59% of sludge proteins. 34.64% of solubilized proteins was present in soluble high molecular; 1.55% and 4.85% broke down to polypeptides and amino acids. The lost proteins via being converted to ammonium and nitrate nitrogen accounted for 9.44% of solubilized proteins. It was important to understand the fate of sludge proteins during TAH pretreatment in terms of protein recovery, which would be helpful for designing the downstream protein separation method and its potential application.     

六溴环十二烷(HBCD)对H4细胞和SK-N-AS细胞脱碘酶2和3表达的影响

六溴环十二烷(hexabromocyclododecane,HBCD)与多溴联苯醚(polybrominated diethyl ethers,PBDEs)复合污染体系,对人类健康尤其神经系统所造成的潜在危害及其机制一直是笔者课题组的研究方向。HBCD是广泛使用的溴化阻燃剂,与PBDEs一样,会通过干扰内分泌系统、影响甲状腺激素分泌及损伤神经系统,对生物体产生发育神经毒性。作为系列研究之一,本研究以H4人脑神经胶质瘤细胞和SK-N-AS人神经母细胞瘤细胞为体外生物模型,通过观察HBCD对H4细胞Ⅱ型脱碘酶(Dio2)和SK-N-AS细胞Ⅲ型脱碘酶(Dio3)表达的调控,初步探讨了HBCD对神经系统局部甲状腺激素水平的潜在影响。H4细胞和SK-N-AS细胞分别暴露于0、1、3和9μmol·L-1HBCD 24 h后,采用MTT法检测细胞活力,Western Blot和RT-PCR法分别分析Dio2和Dio3蛋白和基因的表达,酶联免疫吸附测定(ELISA)法检测H4细胞脑源性神经细胞营养因子(BDNF)的分泌。结果表明,HBCD以剂量依赖方式降低H4细胞和SK-N-AS细胞生存率,引起H4细胞Dio2蛋白和基因表达下调,而致SK-N-AS细胞Dio3蛋白和基因表达上调。此外,HBCD还降低H4细胞BDNF的分泌。这表明,HBCD很可能通过影响神经和胶质细胞脱碘酶的表达,影响脑局部甲状腺激素水平,从而引起神经系统损伤及发育神经毒性。     

Incorporating basic needs to reconcile poverty and ecosystem services

Conservation managers frequently face the challenge of protecting and sustaining biodiversity without producing detrimental outcomes for (often poor) human populations that depend on ecosystem services for their well-being. However, mutually beneficial solutions are often elusive and can mask trade-offs and negative outcomes for people. To deal with such trade-offs, ecological and social thresholds need to be identified to determine the acceptable solution space for conservation. Although human well-being as a concept has recently gained prominence, conservationists still lack tools to evaluate how their actions affect it in a given context. We applied the theory of human needs to conservation by building on an extensive historical application of need approaches in international development. In an innovative participatory method that included focus groups and household surveys, we evaluated how human needs are met based on locally relevant thresholds. We then established connections between human needs and ecosystem services through key-informant focus groups. We applied our method in coastal East Africa to identify households that would not be able to meet their basic needs and to uncover the role of ecosystem services in meeting these. This enabled us to identify how benefits derived from the environment were contributing to meeting basic needs and to consider potential repercussions that could arise through changes to ecosystem service provision. We suggest our approach can help conservationists and planners balance poverty alleviation and biodiversity protection and ensure conservation measures do not, at the very least, cause serious harm to individuals. We further argue it can be used as a basis for monitoring the impacts of conservation on multidimensional poverty.     

A multispecies assessment of wildlife impacts on local community livelihoods

Conflicts between the interests of agriculture and wildlife conservation are a major threat to biodiversity and human well-being globally. Addressing such conflicts requires a thorough understanding of the impacts associated with living alongside protected wildlife. Despite this, most studies reporting on human–wildlife impacts and the strategies used to mitigate them focus on a single species, thus oversimplifying often complex systems of human–wildlife interactions. We sought to characterize the spatiotemporal patterns of impacts by multiple co-occurring species on agricultural livelihoods in the eastern Okavango Delta Panhandle in northern Botswana through the use of a database of 3264 wildlife-incident reports recorded from 2009 to 2015 by the Department of Wildlife and National Parks. Eight species (African elephants [Loxodonta africana], hippopotamuses [Hippopotamus amphibious], lions [Panthera leo], cheetah [Acinonyx jubatus], African wild dogs [Lycaon pictus], hyenas [Crocuta crocuta], leopards [Panthera pardus], and crocodiles [Crocodylus niloticus]) appeared on incident reports, of which 56.5% were attributed to elephants. Most species were associated with only 1 type of damage (i.e., either crop damage or livestock loss). Carnivores were primarily implicated in incident reports related to livestock loss, particularly toward the end of the dry season (May–October). In contrast, herbivores were associated with crop-loss incidents during the wet season (November–April). Our results illustrate how local communities can face distinct livelihood challenges from different species at different times of the year. Such a multispecies assessment has important implications for the design of conservation interventions aimed at addressing the costs of living with wildlife and thereby mitigation of the underlying conservation conflict. Our spatiotemporal, multispecies approach is widely applicable to other regions where sustainable and long-term solutions to conservation conflicts are needed for local communities and biodiversity.