SO2污染对小鼠骨髓细胞微核的诱发作用

在SO2吸入慢性染毒条件下,小鼠骨髓嗜多染红细胞（PCE）的微核细胞率与微核率均显著增加,且雌雄差异显著。结果也表明,SO2对阳性致突变剂乌拉坦航发微核的作用有显著抑制效应。本研究模拟SO2空气污染,从整体水平直接证实了SO2是哺乳类细胞染色体断裂剂、SO2与阳性致突变剂的联合作用是复杂的结论。     

Detection of fetal HLA-DQα sequences in maternal blood: A gender-independent technique of fetal cell identification

The objective of this study was to detect fetal HLA-DQα gene sequences in maternal blood. HLA-DQα genotypes of 70 pregnant women and their partners were determined for type A1. We specifically sought couples where the father, but not the mother, had genotype A1. In 12 women, maternal blood samples were flow-sorted. Candidate fetal cells were isolated and amplified by using PCR primers specific for a paternal HLA-DQα A1 allele. Fetal HLA-DQα A1 genotype was predicted from sorted cells; amniocytes or cheek swabs were used for confirmation. Six of twelve sorted samples had amplification products indicating the presence of the HLA-DQα A1 allele; 6/12 did not. Prediction of the fetal genotype was 100 per cent correct, as determined by subsequent amplification of amniocytes or cheek swabs. We conclude that paternally inherited uniquely fetal HLA-DQα gene sequences can be identified in maternal blood. This system permits the identification of fetal cells independent of fetal gender, and has the potential for non-invasive prenatal diagnosis of paternally inherited conditions.     

Rapid prenatal diagnosis of aneuploidy from uncultured amniotic fluid cells using five-colour fluorescence in situ hybridization

In this paper we describe the use of five-colour fluorescence in situ hybridization for prenatal diagnosis of aneuploidy using uncultured amniotic fluid cells. The analysis is based on ratio mixing of dual-labelled probes and digital imaging for the detection and visualization of five different probes specific for the five target chromosomes, 13, 18, 21, X, and Y. A retrospective blind analysis of 30 coded uncultured amniotic fluid samples correctly detected fetal sex and five trisomy 21 cases. Multicolour fluorescence in situ hybridization used in this way allows rapid and simultaneous detection of the most frequent aneuploidies.     

Analysis on reasons for the Yellow River''s dry-up and its  eco-environmental impacts

The Yellow River, or Huanghe, is one of the most important river in China. It is the major water resources for north and northwest China. Since 1972, the Yellow River's dry-up has occurred frequently and become even more year by year. Except the huge loss to social life and economic development, the Yellow River's dry-up brings about great impacts to eco-environment. This paper analyzed the reasons and impacts from multi-aspect: effects of climate change, influence of human activities and impacts to delta's eco-environment, aquatic life resources, agricultural eco- environment, water pollution and flood prevention as well.     

大气飘尘对大鼠肺细胞的毒性比较

采用大白鼠气管内注入飘尘后分析肺灌洗液的方法，比较了上海不同地区飘尘对大鼠肺细胞的毒性；再运用毒性指数及效应指数，综合评价了上海市不同地区大气飘尘污染的状况。研究表明：从肺灌洗液的生化成份分析及细胞分类显示，以彭浦新村、隆昌路平凉路、康定路胶州路３个点的飘尘毒性较大。综合评价结果，彭浦新村的效应指数最大，以后依次为康定路胶州路、鲁班路斜土路、青云路、隆昌路平凉路等。     

Residents' preparedness and response to the Kalamazoo Tornado

A survey was conducted of individuals residing directly in the path of the tornado that hit Kalamazoo, Michigan, on 13th May 1980. The residents' tornado preparedness and response were examined in an effort to evaluate the city's emergency warning system. The system was adequate for people on the east side of the city and lacking for west side residents. Other factors pertaining to the storm event and human response were also evaluated.     

人因评价的定量化研究

人因评价是安全评价中的重要组成部分，在结合层次分析法和综合加权法的基础上，建立了人因评价的量化模型。     

事故前人因失误研究

在安全评价中，人因失误特别是事故后人因失误越来越受到重视；但相对而言，事故前人因失误没有引起足够的重视。本通过对大量核电厂安全分析报告和运行事件报告的考察，系统地阐述了事故前人因失误对系统安全的显影响，并在此基础上，归纳出在核电站开展事故前人因(失误)分析的程序。该程序主要包括系统熟悉，定性分析，筛选，定量计算，与故障树的集成，敏感性分析与不确定性分析，形成分析档等几个步骤。     

重庆城区地貌灾害的发展趋势及减灾研究

根据对重庆城区20世纪80年代以来发生的地貌灾害的分析研究，认识到其地貌灾害的成因及变化趋势，即时间上的周期性、空间上的分散性、地域上的转移性，并针对其发展趋势提出了相应的防治措施。     

现代企业人力资源战略分析

人力资源的战略化管理是知识经济时代的必然要求和未来发展趋势。人力资源战略处于企业职能战略的核心地位，通过对企业人力资源战略分析必须考虑的内、外部环境因素的研究，提出了现代企业人力资源战略分析的基本理论框架，并对企业实施人力资源战略化管理进行了理论探索。