Chorionic villus sampling and acceptance rate of prenatal diagnosis

In this paper, we compared the acceptance rate of fetal diagnosis for β-thalassemia in three group of couples of Sardinian descent; the first counselled before DNA analysis was available, the second presenting after DNA analysis was introduced but too late for chorionic villus sampling and thus monitored by amniocyte DNA analysis and the third presenting within the first trimester after DNA analysis was introduced and thus in time for trophoblast DNA analysis. A higher proportion of couples from the latter group opted for fetal testing as compared to the 1st and 2nd group. These results indicate that in this population, introduction of 1st trimester diagnosis made prenatal testing acceptable to practically all counselled couples at risk.     

水中阴离子表面活性剂的测量不确定度评定

简要介绍了测量不确定度的概念，运用《测量不确定度评定与表示》的技术规范，通过对阴离子表面活性剂的测定过程，分析了影响阴离子表面活性剂测量不确定度的因素，给出了相对标准不确定度分量，并具体阐明了测量不确定度的评定步骤，得出测量扩展不确定度的结果。     

GOALS AND DATA COLLECTION DESIGNS FOR WATER QUALITY MONITORING1

ABSTRACT: Water quality monitoring cannot address every information need through one data collection procedure. This paper discusses the goals and related procedures for designing water quality monitoring programs. The discussion focuses on the broad information needs of those agencies operating water quality networks. These information needs include the ability to assess trends and environmental impacts, determine compliance with objectives or standards, estimate mass transport, and perform general surveillance. Each of these information needs has different data requirements. This paper outlines these goals and discusses factors to consider in developing a monitoring plan on a site by site basis.     

NEW ZEALAND'S NATIONAL WATER QUALITY MONITORING NETWORK - DESIGN AND FIRST YEAR'S OPERATION1

ABSTRACT: The design and implementation of a national surface water quality monitoring network for New Zealand are described. Some of the lessons learned from the first year of operation are also addressed. Underpinning the design, and specified in advance, are the goal and objectives, the data quality assurance system, and the mechanism for data interpretation and reporting. Because of the difficulties associated with the use of a multitude of different agencies, only one agency is involved in field work and one laboratory undertakes the analysis. Staff training has been given a high priority. The network has been designed to give good trend detectability for regular sampling over a 5–10 year period.     

Effects of multitasking on operator performance using computational and auditory tasks

This study investigated the effects of multiple cognitive tasks on human performance. Twenty-four students at North Carolina A&;T State University participated in the study. The primary task was auditory signal change perception and the secondary task was a computational task. Results showed that participants' performance in a single task was statistically significantly different from their performance in combined tasks: (a) algebra problems (algebra problem primary and auditory perception secondary); (b) auditory perception tasks (auditory perception primary and algebra problems secondary); and (c) mean false-alarm score in auditory perception (auditory detection primary and algebra problems secondary). Using signal detection theory (SDT), participants' performance measured in terms of sensitivity was calculated as ?0.54 for combined tasks (algebra problems the primary task) and ?0.53 auditory perceptions the primary task. During auditory perception tasks alone, SDT was found to be 2.51. Performance was 83% in a single task compared to 17% when combined tasks.     

空气中恶臭气体的官能测定研究

本文参照国外资料,结合国内的恶臭污染状况及实验条件,建立了以无臭气为参比的改进三点比较式臭袋法的官能实验方法.本法利用人的嗅觉功能对恶臭空气进行检测,所得结果具有可比性,是一种可靠的、简便的、易推广的方法.     

Noninvasive prenatal diagnosis of aneuploidy using cell-free nucleic acids in maternal blood: promises and unanswered questions

The discovery of cell-free fetal (cff) DNA and RNA in the maternal circulation has driven developments in noninvasive prenatal diagnosis (NIPD) for the past decade. Detection of paternally derived alleles in cff DNA is becoming well established. Now much interest is focussing on NIPD of fetal chromosomal abnormalities, such as trisomy 21, which is a considerable challenge because this demands accurate quantitative measurements of the amounts of specific cff DNA or cff RNA sequences in maternal blood samples. Emerging strategies for distinguishing and quantifying the fetal nucleic acids in the maternal circulation promise continued development of the field, and pose a number of unanswered questions. Copyright © 2007 John Wiley & Sons, Ltd.